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Select item 107019561.

Silencing HOXC13 exerts anti-prostate cancer effects by inducing DNA damage and activating cGAS/STING/IRF3 pathway

Maozhang Li, Guangwei Bai, Yi Cen, Qitong Xie, Jiahong Chen, Jia Chen, Qingbiao Chen, Weide Zhong, Xiaobo Zhou

J Transl Med. 2023; 21: 884. Published online 2023 Dec 6. doi: 10.1186/s12967-023-04743-x

PMCID:: PMC10701956

Abstract Article PDF–5.0M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104998213.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 99575144.

Variants Identified in the HOXC13 and HOXD13 Genes Suggest Association with Cervical Cancer in a Cohort of Mexican Women

Karina Janett Juárez-Rendón, Manuel Alejandro Castro-García, Diddier Giovanni Prada-Ortega, Gildardo Rivera, Luz María Ruíz-Godoy, Virginia Isabel Enríquez-Cárcamo, Miguel Angel Reyes-Lopez

Genes (Basel) 2023 Feb; 14(2): 358. Published online 2023 Jan 30. doi: 10.3390/genes14020358

PMCID:: PMC9957514

Abstract Article PDF–693K

Select item 97080865.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 83529646.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 80090487.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 78891008.

HOXC-AS2 mediates the proliferation, apoptosis, and migration of non-small cell lung cancer by combining with HOXC13 gene

Bin Liu, Jing Li, Ji-Man Li, Guang-Yuan Liu, Yong-Sheng Wang

Cell Cycle. 2021; 20(2): 236–246. Published online 2021 Jan 11. doi: 10.1080/15384101.2020.1868161

PMCID:: PMC7889100

Abstract Article PDF–12M

Select item 76571799.

Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan

Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura

Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186

PMCID:: PMC7657179

Abstract Article PDF–225K

Select item 607643910.

The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation

Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin

Cancer Res. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342

PMCID:: PMC6076439

Abstract Article PDF–2.5M

Select item 579781211.

HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3

Jing Luo, Zhongqiu Wang, Jianfeng Huang, Yu Yao, Qi Sun, Jie Wang, Yi Shen, Lin Xu, Binhui Ren

Cancer Sci. 2018 Feb; 109(2): 317–329. Published online 2017 Dec 20. doi: 10.1111/cas.13453

PMCID:: PMC5797812

Abstract Article PDF–2.4M

Select item 538914212.

A novel mutation in homeobox DNA binding domain of HOXC13 gene underlies pure hair and nail ectodermal dysplasia (ECTD9) in a Pakistani family

Anwar Kamal Khan, Noor Muhammad, Abdul Aziz, Sher Alam Khan, Khadim Shah, Abdul Nasir, Muzammil Ahmad Khan, Saadullah Khan

BMC Med Genet. 2017; 18: 42. Published online 2017 Apr 12. doi: 10.1186/s12881-017-0402-y

PMCID:: PMC5389142

Abstract Article PDF–1.7M

Select item 507302713.

Transcriptional regulation of the proto‐oncogene Zfp521 by SPI1 (PU.1) and HOXC13

Ming Yu, Salma Al‐Dallal, Latifa Al‐Haj, Shiraj Panjwani, Akina S. McCartney, Sarah M. Edwards, Pooja Manjunath, Catherine Walker, Alexander Awgulewitsch, Kathryn E. Hentges

Genesis. 2016 Oct; 54(10): 519–533. Published online 2016 Aug 29. doi: 10.1002/dvg.22963

PMCID:: PMC5073027

Abstract Article PDF–1.9M

Select item 495594214.

Deletions of 5’ HOXC genes are associated with lower extremity malformations including clubfoot and vertical talus

David M. Alvarado, Kevin McCall, Jacqueline T. Hecht, Matthew B. Dobbs, Christina A. Gurnett

J Med Genet. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: J Med Genet. 2016 Apr; 53(4): 250–255. Published online 2016 Jan 4. doi: 10.1136/jmedgenet-2015-103505

PMCID:: PMC4955942

Abstract Article PDF–1.4M

Select item 437270215.

YAP Regulates the Expression of Hoxa1 and Hoxc13 in Mouse and Human Oral and Skin Epithelial Tissues

Ming Liu, Shuangyun Zhao, Qingjie Lin, Xiu-Ping Wang

Mol Cell Biol. 2015 Apr; 35(8): 1449–1461. Prepublished online 2015 Feb 17. Published online 2015 Mar 24. doi: 10.1128/MCB.00765-14

PMCID:: PMC4372702

Abstract Article PDF–4.0M

Select item 433215016.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen

Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504

PMCID:: PMC4332150

Abstract Article PDF–2.8M

Select item 432144417.

Genome-wide association study of selenium concentrations

Marilyn C. Cornelis, Myriam Fornage, Millennia Foy, Pengcheng Xun, Vadim N. Gladyshev, Steve Morris, Daniel I. Chasman, Frank B. Hu, Eric B. Rimm, Peter Kraft, Joanne M. Jordan, Dariush Mozaffarian, Ka He

Hum Mol Genet. 2015 Mar 1; 24(5): 1469–1477. Published online 2014 Oct 24. doi: 10.1093/hmg/ddu546

PMCID:: PMC4321444

Abstract Article PDF–252K

Select item 383995118.

Hyperexpression of HOXC13, located in the 12q13 chromosomal region, in well-differentiated and dedifferentiated human liposarcomas

MONICA CANTILE, FRANCESCA GALLETTA, RENATO FRANCO, GABRIELLA AQUINO, GIOSUÈ SCOGNAMIGLIO, LAURA MARRA, MARGHERITA CERRONE, GABRIELLA MALZONE, ANGELA MANNA, GAETANO APICE, FLAVIO FAZIOLI, GERARDO BOTTI, ANNAROSARIA DE CHIARA

Oncol Rep. 2013 Dec; 30(6): 2579–2586. Published online 2013 Oct 1. doi: 10.3892/or.2013.2760

PMCID:: PMC3839951

Abstract Article PDF–513K

Select item 348712219.

Loss-of-Function Mutations in HOXC13 Cause Pure Hair and Nail Ectodermal Dysplasia

Zhimiao Lin, Quan Chen, Lei Shi, Mingyang Lee, Kathrin A. Giehl, Zhanli Tang, Huijun Wang, Jie Zhang, Jinghua Yin, Lingshen Wu, Ruo Xiao, Xuanzhu Liu, Lanlan Dai, Xuejun Zhu, Ruoyu Li, Regina C. Betz, Xue Zhang, Yong Yang

Am J Hum Genet. 2012 Nov 2; 91(5): 906–911. doi: 10.1016/j.ajhg.2012.08.029

PMCID:: PMC3487122

Abstract Article PDF–736K

Select item 347820620.

Increased HOX C13 expression in metastatic melanoma progression

Monica Cantile, Giosuè Scognamiglio, Annamaria Anniciello, Marisa Farina, Giusy Gentilcore, Clemente Santonastaso, Franco Fulciniti, Clemente Cillo, Renato Franco, Paolo A Ascierto, Gerardo Botti

J Transl Med. 2012; 10: 91. Published online 2012 May 14. doi: 10.1186/1479-5876-10-91