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Select item 109949371.

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy

Jean-Louis A. Parmasad, Konrad M. Ricke, Benjamin Nguyen, Morgan G. Stykel, Brodie Buchner-Duby, Amanda Bruce, Haley M. Geertsma, Eric Lian, Nathalie A. Lengacher, Steve M. Callaghan, Alvin Joselin, Julianna J. Tomlinson, Michael G. Schlossmacher, William L. Stanford, Jiyan Ma, Patrik Brundin, Scott D. Ryan, Maxime W. C. Rousseaux

Cell Death Dis. 2024 Apr; 15(4): 246. Published online 2024 Apr 4. doi: 10.1038/s41419-024-06534-8

PMCID:: PMC10994937

Abstract Article PDF–3.4M

Select item 104409162.

P300/SP1 complex mediating elevated METTL1 regulates CDK14 mRNA stability via internal m7G modification in CRPC

Mingpeng Zhang, Duo Kan, Boya Zhang, Xueqiao Chen, Chun Wang, Songmao Chen, Wenlong Gao, Zhao Yang, Yang Li, Yutong Chen, Shimiao Zhu, Simeng Wen, Yuanjie Niu, Zhiqun Shang

J Exp Clin Cancer Res. 2023; 42: 215. Published online 2023 Aug 21. doi: 10.1186/s13046-023-02777-z

PMCID:: PMC10440916

Abstract Article PDF–4.3M

Select item 100729063.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 87487895.

Systematic identification of NF90 target RNAs by iCLIP analysis

Valeria Lodde, Matteo Floris, Rachel Munk, Jennifer L. Martindale, Davide Piredda, Catello Mario Panu Napodano, Francesco Cucca, Sergio Uzzau, Kotb Abdelmohsen, Myriam Gorospe, Ji Heon Noh, M. Laura Idda

Sci Rep. 2022; 12: 364. Published online 2022 Jan 10. doi: 10.1038/s41598-021-04101-1

PMCID:: PMC8748789

Abstract Article PDF–4.2M

Select item 87418556.

CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA

Simin Chen, Zhaoyu Zhang, Baoxin Zhang, Qing Huang, Yi Liu, Yi Qiu, Xinmiao Long, Minghua Wu, Zuping Zhang

Int J Biol Sci. 2022; 18(2): 841–857. Published online 2022 Jan 1. doi: 10.7150/ijbs.66114

PMCID:: PMC8741855

Abstract Article PDF–3.9M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78387398.

Knockdown of PFTAIRE Protein Kinase 1 (PFTK1) Inhibits Proliferation, Invasion, and EMT in Colon Cancer Cells

Jiankang Zhu, Chongzhong Liu, Fengyue Liu, Yadong Wang, Min Zhu

Oncol Res. 2016; 24(3): 137–144. Published online 2016 Jul 18. doi: 10.3727/096504016X14611963142218

PMCID:: PMC7838739

Abstract Article PDF–3.1M

Select item 78386049.

Knockdown of PFTK1 Expression by RNAi Inhibits the Proliferation and Invasion of Human Non-Small Lung Adenocarcinoma Cells

Mei-han Liu, Shao-min Shi, Kai Li, En-qi Chen

Oncol Res. 2016; 24(3): 181–187. Published online 2016 Jul 18. doi: 10.3727/096504016X14635761799038

PMCID:: PMC7838604

Abstract Article PDF–4.7M

Select item 756688110.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 741580311.

CircCDK14 protects against Osteoarthritis by sponging miR-125a-5p and promoting the expression of Smad2

Panyang Shen, Yute Yang, Gang Liu, Weijie Chen, Junxing Chen, Qingxin Wang, Hongliang Gao, Shunwu Fan, Shuying Shen, Xing Zhao

Theranostics. 2020; 10(20): 9113–9131. Published online 2020 Jul 11. doi: 10.7150/thno.45993

PMCID:: PMC7415803

Abstract Article PDF–3.4M

Select item 732565312.

Upregulation of miR-1825 inhibits the progression of glioblastoma by suppressing CDK14 though Wnt/β-catenin signaling pathway

Fengqin Lu, Chunhong Li, Yuping Sun, Ting Jia, Na Li, Haiyan Li

World J Surg Oncol. 2020; 18: 147. Published online 2020 Jun 30. doi: 10.1186/s12957-020-01927-3

PMCID:: PMC7325653

Abstract Article PDF–5.1M

Select item 677813713.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 660598214.

The role of lncRNA MSC-AS1/miR-29b-3p axis-mediated CDK14 modulation in pancreatic cancer proliferation and Gemcitabine-induced apoptosis

Yunpeng Sun, Pengfei Wang, Wenjun Yang, Yunfeng Shan, Qiyu Zhang, Huanhuan Wu

Cancer Biol Ther. 2019; 20(6): 729–739. Published online 2019 Mar 27. doi: 10.1080/15384047.2018.1529121

PMCID:: PMC6605982

Abstract Article PDF–2.3M

Select item 638658815.

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari

Mol Cell. Author manuscript; available in PMC 2020 Feb 21.

Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001

PMCID:: PMC6386588

Abstract Article PDF–1.7M

Select item 612586916.

The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1

Sen-Mao Li, Huan-Lei Wu, Xiao Yu, Kun Tang, Shao-Gang Wang, Zhang-Qun Ye, Jia Hu

J Exp Clin Cancer Res. 2018; 37: 219. Published online 2018 Sep 5. doi: 10.1186/s13046-018-0895-z

PMCID:: PMC6125869

Abstract Article PDF–9.0M

Select item 600157217.

Long non‐coding RNA SNHG15 promotes CDK14 expression via miR‐486 to accelerate non‐small cell lung cancer cells progression and metastasis

Bing Jin, Hua Jin, Hai‐Bo Wu, Jian‐Jun Xu, Bing Li

J Cell Physiol. 2018 Sep; 233(9): 7164–7172. Published online 2018 Apr 6. doi: 10.1002/jcp.26543

PMCID:: PMC6001572

Abstract Article PDF–1.9M

Select item 599939618.

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel

eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879

PMCID:: PMC5999396

Abstract Article PDF–3.6M

Select item 582692619.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 579783120.

Downregulation of dual‐specificity tyrosine‐regulated kinase 2 promotes tumor cell proliferation and invasion by enhancing cyclin‐dependent kinase 14 expression in breast cancer

Yoshimi Imawari, Rei Mimoto, Shinichi Hirooka, Toshiaki Morikawa, Hiroshi Takeyama, Kiyotsugu Yoshida

Cancer Sci. 2018 Feb; 109(2): 363–372. Published online 2018 Jan 13. doi: 10.1111/cas.13459

PMCID:: PMC5797831

Abstract Article PDF–1.0M

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