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Select item 112282021.

ZFHX3 variants cause childhood partial epilepsy and infantile spasms with favourable outcomes

Ming-Feng He, Li-Hong Liu, Sheng Luo, Juan Wang, Jia-Jun Guo, Peng-Yu Wang, Qiong-Xiang Zhai, Su-Li He, Dong-Fang Zou, Xiao-Rong Liu, Bing-Mei Li, Hai-Yan Ma, Jing-Da Qiao, Peng Zhou, Na He, Yong-Hong Yi, Wei-Ping Liao

J Med Genet. 2024 Jul; 61(7): 652–660. Published online 2024 Mar 20. doi: 10.1136/jmg-2023-109725

PMCID:: PMC11228202

Abstract Article PDF–4.4M

Select item 111439272.

Myeloid Zfhx3 deficiency protects against hypercapnia-induced suppression of host defense against influenza A virus

S. Marina Casalino-Matsuda, Fei Chen, Francisco J. Gonzalez-Gonzalez, Hiroaki Matsuda, Aisha Nair, Hiam Abdala-Valencia, G.R. Scott Budinger, Jin-Tang Dong, Greg J. Beitel, Peter H.S. Sporn

JCI Insight. 2024 Feb 22; 9(4): e170316. Published online 2024 Jan 16. doi: 10.1172/jci.insight.170316

PMCID:: PMC11143927

Abstract Article PDF–9.2M

Select item 109920063.

ZFHX3 mutation as a protective biomarker for immune checkpoint blockade in non-small cell lung cancer

Jiexia Zhang, Ningning Zhou, Anqi Lin, Peng Luo, Xin Chen, Huojin Deng, Shijun Kang, Linlang Guo, Weiliang Zhu, Jian Zhang

Cancer Immunol Immunother. 2021 Jan; 70(1): 137–151. Published online 2020 Jul 11. doi: 10.1007/s00262-020-02668-8

PMCID:: PMC10992006

Abstract Article PDF–5.7M

Select item 109332674.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 108067395.

Exonic trinucleotide repeat expansions in ZFHX3 cause spinocerebellar ataxia type 4: A poly-glycine disease

Joel Wallenius, Efthymia Kafantari, Emma Jhaveri, Sorina Gorcenco, Adam Ameur, Christin Karremo, Sigurd Dobloug, Kristina Karrman, Tom de Koning, Andreea Ilinca, Maria Landqvist Waldö, Andreas Arvidsson, Staffan Persson, Elisabet Englund, Hans Ehrencrona, Andreas Puschmann

Am J Hum Genet. 2024 Jan 4; 111(1): 82–95. Published online 2023 Nov 29. doi: 10.1016/j.ajhg.2023.11.008

PMCID:: PMC10806739

Abstract Article PDF–2.7M

Select item 105658766.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105275547.

Loss of the Atrial Fibrillation-Related Gene, Zfhx3, Results in Atrial Dilation and Arrhythmias

Heather S. Jameson, Alan Hanley, Matthew C. Hill, Ling Xiao, Jiangchuan Ye, Aneesh Bapat, Elsa Ronzier, Amelia Weber Hall, William J. Hucker, Sebastian Clauss, Miranda Barazza, Elizabeth Silber, Julie Mina, Nathan R. Tucker, Robert W. Mills, Jin-Tang Dong, David J. Milan, Patrick T. Ellinor

Circ Res. Author manuscript; available in PMC 2024 Aug 4.

Published in final edited form as: Circ Res. 2023 Aug 4; 133(4): 313–329. Published online 2023 Jul 14. doi: 10.1161/CIRCRESAHA.123.323029

PMCID:: PMC10527554

Abstract Article PDF–3.5M

Select item 98201268.

Inactivation of PTEN and ZFHX3 in Mammary Epithelial Cells Alters Patterns of Collective Cell Migration

Ali Dayoub, Artem I. Fokin, Maria E. Lomakina, John James, Marina Plays, Tom Jacquin, Nikita M. Novikov, Rostislav S. Vorobyov, Anastasia A. Schegoleva, Karina D. Rysenkova, Julia Gaboriaud, Sergey V. Leonov, Evgeny V. Denisov, Alexis M. Gautreau, Antonina Y. Alexandrova

Int J Mol Sci. 2023 Jan; 24(1): 313. Published online 2022 Dec 24. doi: 10.3390/ijms24010313

PMCID:: PMC9820126

Abstract Article PDF–3.9M

Select item 97696989.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 972799910.

ATBF1 is a potential diagnostic marker of histological grade and functions via WNT5A in breast cancer

Mei Li, Yanan Zheng, Xujun Li, Xiaohan Shen, Tingxia Zhang, Bowen Weng, Haijiao Mao, Jiyuan Zhao

BMC Cancer. 2022; 22: 1280. Published online 2022 Dec 7. doi: 10.1186/s12885-022-10380-2

PMCID:: PMC9727999

Abstract Article PDF–8.0M

Select item 943393811.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 934647112.

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2‐mediated degradation

Mi Chen, Shreyas Lingadahalli, Nitin Narwade, Kate Man Kei Lei, Shanshan Liu, Zuxianglan Zhao, Yimin Zheng, Qian Lu, Alexander Hin Ning Tang, Terence Chuen Wai Poon, Edwin Cheung

EMBO Rep. 2022 Aug; 23(8): e53468. Published online 2022 Jul 4. doi: 10.15252/embr.202153468

PMCID:: PMC9346471

Abstract Article PDF–5.2M

Select item 927928513.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 882889514.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 881713815.

AR imposes different effects on ZFHX3 transcription depending on androgen status in prostate cancer cells

Xing Fu, Zhiqian Zhang, Mingcheng Liu, Juan Li, Jun A, Liya Fu, Chenyang Huang, Jin‐Tang Dong

J Cell Mol Med. 2022 Feb; 26(3): 800–812. Published online 2021 Dec 24. doi: 10.1111/jcmm.17125

PMCID:: PMC8817138

Abstract Article PDF–1.3M

Select item 876331716.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 866386717.

Association between the rs2106261 polymorphism in the zinc finger homeobox 3 gene and risk of atrial fibrillation: Evidence from a PRISMA-compliant meta-analysis

Yue Wei, Lingjie Wang, Changjian Lin, Yun Xie, Yangyang Bao, Qingzhi Luo, Ning Zhang

Medicine (Baltimore) 2021 Dec 10; 100(49): e27749. Published online 2021 Dec 10. doi: 10.1097/MD.0000000000027749

PMCID:: PMC8663867

Abstract Article PDF–816K

Select item 836418118.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 824686319.

Cross‐linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex

Cornelia G. Spruijt, Cathrin Gräwe, Simone C. Kleinendorst, Marijke P. A. Baltissen, Michiel Vermeulen

FEBS J. 2021 May; 288(10): 3231–3245. Published online 2020 Dec 14. doi: 10.1111/febs.15650

PMCID:: PMC8246863

Abstract Article PDF–3.1M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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