PMC Links for GEO Profiles (Select 132114175) - PMC

Select item 101124291.

A Par3/LIM Kinase/Cofilin Pathway Mediates Human Airway Smooth Muscle Relaxation by TAS2R14

Jung-A A. Woo, Maria Castaño, Teresa R. Kee, Jordan Lee, Cynthia J. Koziol-White, Steven S. An, Donghwa Kim, David E. Kang, Stephen B. Liggett

Am J Respir Cell Mol Biol. 2023 Apr 1; 68(4): 417–429. Published online 2023 Jan 20. doi: 10.1165/rcmb.2022-0303OC

PMCID:: PMC10112429

Abstract Article PDF–2.6M

Select item 85382282.

Neuropeptide Y Reduces Nasal Epithelial T2R Bitter Taste Receptor–Stimulated Nitric Oxide Production

Ryan M. Carey, Nithin D. Adappa, James N. Palmer, Robert J. Lee

Nutrients. 2021 Oct; 13(10): 3392. Published online 2021 Sep 27. doi: 10.3390/nu13103392

PMCID:: PMC8538228

Abstract Article PDF–2.2M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79491054.

The short third intracellular loop and cytoplasmic tail of bitter taste receptors provide functionally relevant GRK phosphorylation sites in TAS2R14

Donghwa Kim, Maria Castaño, Lauren K. Lujan, Jung A. Woo, Stephen B. Liggett

J Biol Chem. 2021 Jan-Jun; 296: 100216. Published online 2021 Jan 16. doi: 10.1074/jbc.RA120.016056

PMCID:: PMC7949105

Abstract Article PDF–1.8M

Select item 69026895.

Differential long-term regulation of TAS2R14 by structurally distinct agonists

Jung A. Woo, Maria Castaño, Ashley Goss, Donghwa Kim, Eric M. Lewandowski, Yu Chen, Stephen B. Liggett

FASEB J. 2019 Nov; 33(11): 12213–12225. Published online 2019 Aug 20. doi: 10.1096/fj.201802627RR

PMCID:: PMC6902689

Abstract Article

Select item 56306006.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 55162957.

Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via G_αi1,2,3

Donghwa Kim, Jung A. Woo, Ezekiel Geffken, Steven S. An, Stephen B. Liggett

Am J Respir Cell Mol Biol. 2017 Jun; 56(6): 762–771. doi: 10.1165/rcmb.2016-0373OC

PMCID:: PMC5516295

Abstract Article PDF–1.3M

Select item 54372528.

Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor

Benjamin M. Hariri, Derek B. McMahon, Bei Chen, Jenna R. Freund, Corrine J. Mansfield, Laurel J. Doghramji, Nithin D. Adappa, James N. Palmer, David W. Kennedy, Danielle R. Reed, Peihua Jiang, Robert J. Lee

J Biol Chem. 2017 May 19; 292(20): 8484–8497. Published online 2017 Apr 3. doi: 10.1074/jbc.M116.771949

PMCID:: PMC5437252

Abstract Article PDF–3.6M

Select item 50161589.

β₂-Adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function

Donghwa Kim, Susan H. Pauer, Hwan M. Yong, Steven S. An, Stephen B. Liggett

J Biol Chem. 2016 Aug 19; 291(34): 17616–17628. Published online 2016 Jun 24. doi: 10.1074/jbc.M116.722736

PMCID:: PMC5016158

Abstract Article PDF–3.1M

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 289317311.

A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer

Daniele Campa, Pavel Vodicka, Barbara Pardini, Alessio Naccarati, Maura Carrai, Ludmila Vodickova, Jan Novotny, Kari Hemminki, Asta Försti, Roberto Barale, Federico Canzian

BMC Med Genet. 2010; 11: 88. Published online 2010 Jun 9. doi: 10.1186/1471-2350-11-88