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Select item 93563241.

ONECUT1 mutations and variants in diabetes

Anne Philippi, Sandra Heller, Ivan G. Costa, Valérie Senée, Markus Breunig, Zhijian Li, Gino Kwon, Ronan Russell, Anett Illing, Qiong Lin, Meike Hohwieler, Anne Degavre, Pierre Zalloua, Stefan Liebau, Michael Schuster, Johannes Krumm, Xi Zhang, Ryan Geusz, Jacqueline R. Benthuysen, Allen Wang, Joshua Chiou, Kyle Gaulton, Heike Neubauer, Eric Simon, Thomas Klein, Martin Wagner, Gopika Nair, Céline Besse, Claire Dandine-Roulland, Robert Olaso, Jean-François Deleuze, Bernhard Kuster, Matthias Hebrok, Thomas Seufferlein, Maike Sander, Bernhard O. Boehm, Franz Oswald, Marc Nicolino, Cécile Julier, Alexander Kleger

Nat Med. Author manuscript; available in PMC 2022 Aug 6.

Published in final edited form as: Nat Med. 2021 Nov; 27(11): 1928–1940. Published online 2021 Oct 18. doi: 10.1038/s41591-021-01502-7

PMCID:: PMC9356324

Abstract Article PDF–5.4M

Select item 85998462.

Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation

Sandra Heller, Zhijian Li, Qiong Lin, Ryan Geusz, Markus Breunig, Meike Hohwieler, Xi Zhang, Gopika G. Nair, Thomas Seufferlein, Matthias Hebrok, Maike Sander, Cécile Julier, Alexander Kleger, Ivan G. Costa

Commun Biol. 2021; 4: 1298. Published online 2021 Nov 17. doi: 10.1038/s42003-021-02818-3

PMCID:: PMC8599846

Abstract Article PDF–2.3M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80090484.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 65823155.

ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility

Jori van der Raadt, Sebastianus H C van Gestel, Nael Nadif Kasri, Cornelis A Albers

Nucleic Acids Res. 2019 Jun 20; 47(11): 5587–5602. Published online 2019 May 3. doi: 10.1093/nar/gkz273

PMCID:: PMC6582315

Abstract Article PDF–8.9M

Select item 57038786.

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal

Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x

PMCID:: PMC5703878

Abstract Article PDF–3.7M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 49011278.

Homeodomain proteins: an update

Thomas R. Bürglin, Markus Affolter

Chromosoma. 2016; 125: 497–521. Published online 2015 Oct 13. doi: 10.1007/s00412-015-0543-8

PMCID:: PMC4901127

Abstract Article PDF–3.1M

Select item 44423679.

Inhibition of Hepatitis B Virus Gene Expression and Replication by Hepatocyte Nuclear Factor 6

Ruidong Hao, Jing He, Xing Liu, Guozhen Gao, Dan Liu, Lei Cui, Guojun Yu, Wenhui Yu, Yu Chen, Deyin Guo

J Virol. 2015 Apr 15; 89(8): 4345–4355. Published online 2015 Feb 4. doi: 10.1128/JVI.03094-14

PMCID:: PMC4442367

Abstract Article PDF–2.0M

Select item 406833910.

Loss of HNF6 expression correlates with human pancreatic cancer progression

Kelly R. Pekala, Xidi Ma, Peter A. Kropp, Christine P. Petersen, Courtney W. Hudgens, Christine H. Chung, Chanjuan Shi, Nipun Merchant, Anirban Maitra, Anna L. Means, Maureen Gannon

Lab Invest. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Lab Invest. 2014 May; 94(5): 517–527. Published online 2014 Mar 17. doi: 10.1038/labinvest.2014.47

PMCID:: PMC4068339

Abstract Article PDF–2.5M

Select item 389803411.

Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia

Pierre-Paul Prévot, Alexandru Simion, Adrien Grimont, Marta Colletti, Abed Khalaileh, Géraldine Van den Steen, Christine Sempoux, Xiaobo Xu, Véronique Roelants, Jacob Hald, Luc Bertrand, Harry Heimberg, Stephen F. Konieczny, Yuval Dor, Frédéric P. Lemaigre, Patrick Jacquemin

Gut. Author manuscript; available in PMC 2014 Jan 22.

Published in final edited form as: Gut. 2012 Dec; 61(12): 1723–1732. Published online 2012 Jan 22. doi: 10.1136/gutjnl-2011-300266

PMCID:: PMC3898034

Abstract Article PDF–4.8M

Select item 382943112.

Hepatocyte Nuclear Factor 6 Suppresses the Migration and Invasive Growth of Lung Cancer Cells through p53 and the Inhibition of Epithelial-Mesenchymal Transition

Xin-Wang Yuan, Dong-Mei Wang, Ying Hu, Yun-Neng Tang, Wei-Wei Shi, Xiao-Jie Guo, Jian-Guo Song

J Biol Chem. 2013 Oct 25; 288(43): 31206–31216. Published online 2013 Sep 10. doi: 10.1074/jbc.M113.480285

PMCID:: PMC3829431

Abstract Article PDF–4.0M

Select item 359184913.

A CpG Mutational Hotspot in a ONECUT Binding Site Accounts for the Prevalent Variant of Hemophilia B Leyden

Alister P.W. Funnell, Michael D. Wilson, Benoit Ballester, Ka Sin Mak, Jon Burdach, Natisha Magan, Richard C.M. Pearson, Frederic P. Lemaigre, Kathryn M. Stowell, Duncan T. Odom, Paul Flicek, Merlin Crossley

Am J Hum Genet. 2013 Mar 7; 92(3): 460–467. doi: 10.1016/j.ajhg.2013.02.003

PMCID:: PMC3591849

Abstract Article PDF–737K

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 301262415.

Control of Pancreas and Liver Gene Expression by HNF Transcription Factors

Duncan T. Odom, Nora Zizlsperger, D. Benjamin Gordon, George W. Bell, Nicola J. Rinaldi, Heather L. Murray, Tom L. Volkert, Jörg Schreiber, P. Alexander Rolfe, David K. Gifford, Ernest Fraenkel, Graeme I. Bell, Richard A. Young

Science. Author manuscript; available in PMC 2010 Dec 30.

Published in final edited form as: Science. 2004 Feb 27; 303(5662): 1378–1381. doi: 10.1126/science.1089769