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Items: 1 to 20 of 21

1.
Ubiquitin ligase RNF125 targets PD-L1 for ubiquitination and degradation
Meng Wei, Yunhai Mo, Jialong Liu, Jingtong Zhai, Huilong Li, Yixin Xu, Yumeng Peng, Zhihong Tang, Tao Wei, Xiaopan Yang, Linfei Huang, Xiao Shao, Jingfei Li, Li Zhou, Hui Zhong, Congwen Wei, Qiaosheng Xie, Min Min, Feixiang Wu
Front Oncol. 2022; 12: 835603. Published online 2022 Jul 29. doi: 10.3389/fonc.2022.835603
PMCID:
PMC9374197
AbstractArticlePDF–15M
2.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
3.
Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia
Juan Tang, Sha Tu, Guoxin Lin, Hui Guo, Chengkai Yan, Qingjun Liu, Ling Huang, Na Tang, Yizhi Xiao, R. Marshall Pope, Murugesan V.S. Rajaram, Amal O. Amer, Brian M. Ahmer, John S. Gunn, Daniel J. Wozniak, Lijian Tao, Vincenzo Coppola, Liwen Zhang, Wallace Y. Langdon, Jordi B. Torrelles, Stanley Lipkowitz, Jian Zhang
J Exp Med. 2020 Apr 6; 217(4): e20182091. Published online 2020 Jan 30. doi: 10.1084/jem.20182091
PMCID:
PMC7144527
AbstractArticlePDF–6.6M
4.
G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response
Wenping Yang, Yi Ru, Jingjing Ren, Juncui Bai, Junshu Wei, Shaozu Fu, Xiangtao Liu, Dan Li, Haixue Zheng
Cell Death Dis. 2019 Dec; 10(12): 946. Published online 2019 Dec 11. doi: 10.1038/s41419-019-2178-9
PMCID:
PMC6906297
AbstractArticlePDF–2.3M
5.
E3 Ubiquitin Ligase RNF125 Activates Interleukin-36 Receptor Signaling and Contributes to Its Turnover
Siddhartha S. Saha, Gary Caviness, Guanghui Yi, Ernest L. Raymond, M. Lamine Mbow, C. Cheng Kao
J Innate Immun. 2018 Feb; 10(1): 56–69. Published online 2017 Nov 25. doi: 10.1159/000481210
PMCID:
PMC6757159
AbstractArticlePDF–722K
6.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
7.
A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome
Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar
Mol Cell. Author manuscript; available in PMC 2017 Oct 31.
Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004
PMCID:
PMC5663465
AbstractArticlePDF–2.1M
8.
Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF-β1-SMAD3-ID1 signaling pathway
Zhong-Yan Liu, Jin Cao, Jing-Tao Zhang, Guo-Li Xu, Xin-Ping Li, Fang-Tao Wang, Kamar Hasan Ansari, Hassan Mohamed, Yue-Zu Fan
Oncotarget. 2017 Jul 25; 8(30): 49897–49914. Published online 2017 May 25. doi: 10.18632/oncotarget.18180
PMCID:
PMC5564816
AbstractArticlePDF–12M
9.
A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
Marie-José Bijlmakers, João M. C. Teixeira, Roeland Boer, Maxim Mayzel, Pilar Puig-Sàrries, Göran Karlsson, Miquel Coll, Miquel Pons, Bernat Crosas
Sci Rep. 2016; 6: 29232. Published online 2016 Jul 14. doi: 10.1038/srep29232
PMCID:
PMC4944129
AbstractArticlePDF–2.4M
10.
A non‐canonical role of the p97 complex in RIG‐I antiviral signaling
Qian Hao, Shi Jiao, Zhubing Shi, Chuanchuan Li, Xia Meng, Zhen Zhang, Yanyan Wang, Xiaomin Song, Wenjia Wang, Rongguang Zhang, Yun Zhao, Catherine CL Wong, Zhaocai Zhou
EMBO J. 2015 Dec 2; 34(23): 2903–2920. Published online 2015 Oct 16. doi: 10.15252/embj.201591888
PMCID:
PMC4687688
AbstractArticlePDF–3.6M
11.
Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation
Hyungsoo Kim, Dennie T. Frederick, Mitchell P. Levesque, Zachary A. Cooper, Yongmei Feng, Clemens Krepler, Laurence Brill, Yardena Samuels, Nicholas K. Hayward, Ally Perlina, Adriano Piris, Tongwu Zhang, Ruth Halaban, Meenhard M. Herlyn, Kevin M. Brown, Jennifer A. Wargo, Reinhard Dummer, Keith T. Flaherty, Ze’ev A. Ronai
Cell Rep. Author manuscript; available in PMC 2015 Dec 16.
Published in final edited form as: Cell Rep. 2015 Jun 9; 11(9): 1458–1473. Published online 2015 May 28. doi: 10.1016/j.celrep.2015.04.049
PMCID:
PMC4681438
AbstractArticlePDF–1.7M
12.
Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15
Sebastian D. Hayes, Han Liu, Ewan MacDonald, Christopher M. Sanderson, Judy M. Coulson, Michael J. Clague, Sylvie Urbé
J Biol Chem. 2012 Dec 14; 287(51): 43007–43018. Published online 2012 Oct 26. doi: 10.1074/jbc.M112.386938
PMCID:
PMC3522295
AbstractArticlePDF–2.6M
13.
Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks
Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson
Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162
PMCID:
PMC3394952
AbstractArticlePDF–3.3M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis
Marie-José Bijlmakers, Seshu K. Kanneganti, Jonathan N. Barker, Richard C. Trembath, Francesca Capon
Hum Mol Genet. 2011 Aug 15; 20(16): 3129–3137. Published online 2011 May 13. doi: 10.1093/hmg/ddr215
PMCID:
PMC3140818
AbstractArticlePDF–324K
16.
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
Gabriel Markson, Christina Kiel, Russell Hyde, Stephanie Brown, Panagoula Charalabous, Anja Bremm, Jennifer Semple, Jonathan Woodsmith, Simon Duley, Kourosh Salehi-Ashtiani, Marc Vidal, David Komander, Luis Serrano, Paul Lehner, Christopher M. Sanderson
Genome Res. 2009 Oct; 19(10): 1905–1911. doi: 10.1101/gr.093963.109
PMCID:
PMC2765280
AbstractArticlePDF–425K
17.
T CELL REGULATOR RNF125/TRAC-1 BELONGS TO A NOVEL FAMILY OF UBIQUITIN LIGASES WITH ZINC FINGERS AND AN UBIQUITIN-BINDING DOMAIN
Ana Lucia Giannini, Yifang Gao, Marie-José Bijlmakers
Biochem J. Author manuscript; available in PMC 2009 Aug 27.
Published in final edited form as: Biochem J. 2008 Feb 15; 410(1): 101–111. doi: 10.1042/BJ20070995
PMCID:
PMC2733222
AbstractArticlePDF–1.2M
18.
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
Kei-ichiro Arimoto, Hitoshi Takahashi, Takayuki Hishiki, Hideyuki Konishi, Takashi Fujita, Kunitada Shimotohno
Proc Natl Acad Sci U S A. 2007 May 1; 104(18): 7500–7505. Published online 2007 Apr 25. doi: 10.1073/pnas.0611551104
PMCID:
PMC1863485
AbstractArticlePDF–501K
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
Systematic identification of regulatory proteins critical for T-cell activation
Peter Chu, Jorge Pardo, Haoran Zhao, Connie C Li, Erlina Pali, Mary M Shen, Kunbin Qu, Simon X Yu, Betty CB Huang, Peiwen Yu, Esteban S Masuda, Susan M Molineaux, Frank Kolbinger, Gregorio Aversa, Jan de Vries, Donald G Payan, X Charlene Liao
J Biol. 2003; 2(3): 21. Published online 2003 Sep 15. doi: 10.1186/1475-4924-2-21
PMCID:
PMC333404
AbstractArticlePDF–723K

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