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Items: 1 to 20 of 73

1.
INPP5D regulates inflammasome activation in human microglia
Vicky Chou, Richard V. Pearse, II, Aimee J. Aylward, Nancy Ashour, Mariko Taga, Gizem Terzioglu, Masashi Fujita, Seeley B. Fancher, Alina Sigalov, Courtney R. Benoit, Hyo Lee, Matti Lam, Nicholas T. Seyfried, David A. Bennett, Philip L. De Jager, Vilas Menon, Tracy L. Young-Pearse
Nat Commun. 2023; 14: 7552. Published online 2023 Nov 29. doi: 10.1038/s41467-023-42819-w
PMCID:
PMC10684891
AbstractArticlePDF–5.2M
2.
INPP5D/SHIP1: Expression, Regulation and Roles in Alzheimer’s Disease Pathophysiology
Edward O. Olufunmilayo, R. M. Damian Holsinger
Genes (Basel) 2023 Oct; 14(10): 1845. Published online 2023 Sep 23. doi: 10.3390/genes14101845
PMCID:
PMC10606568
AbstractArticlePDF–1.0M
3.
Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk
Andrea Gelemanović, Tatjana Ćatipović Ardalić, Ajka Pribisalić, Caroline Hayward, Ivana Kolčić, Ozren Polašek
Int J Mol Sci. 2023 Apr; 24(8): 7006. Published online 2023 Apr 10. doi: 10.3390/ijms24087006
PMCID:
PMC10138356
AbstractArticlePDF–825K
4.
Expression of INPP5D Isoforms in Human Brain: Impact of Alzheimer’s Disease Neuropathology and Genetics
Diana J. Zajac, James Simpson, Eric Zhang, Ishita Parikh, Steven Estus
Genes (Basel) 2023 Mar; 14(3): 763. Published online 2023 Mar 21. doi: 10.3390/genes14030763
PMCID:
PMC10048252
AbstractArticlePDF–3.7M
5.
SLAMF7 regulates the inflammatory response in macrophages during polymicrobial sepsis
Yongjian Wu, Qiaohua Wang, Miao Li, Juanfeng Lao, Huishu Tang, Siqi Ming, Minhao Wu, Sitang Gong, Linhai Li, Lei Liu, Xi Huang
J Clin Invest. 2023 Mar 15; 133(6): e150224. Published online 2023 Mar 15. doi: 10.1172/JCI150224
PMCID:
PMC10014109
AbstractArticlePDF–20M
6.
CircRNA_0075723 protects against pneumonia-induced sepsis through inhibiting macrophage pyroptosis by sponging miR-155-5p and regulating SHIP1 expression
Dianyin Yang, Dongyang Zhao, Jinlu Ji, Chunxue Wang, Na Liu, Xiaowei Bao, Xiandong Liu, Sen Jiang, Qianqian Zhang, Lunxian Tang
Front Immunol. 2023; 14: 1095457. Published online 2023 Feb 27. doi: 10.3389/fimmu.2023.1095457
PMCID:
PMC10008927
AbstractArticlePDF–6.0M
7.
Multistep IgE Mast Cell Desensitization Is a Dose- and Time-Dependent Process Partially Regulated by SHIP-1
Ather Adnan, Shree Acharya, Leila A. Alenazy, Leticia de las Vecillas, Pedro Giavina Bianchi, Matthieu Picard, Lucia Calbache-Gil, Salvador Romero-Pinedo, Ana Clara Abadí´a-Molina, William Kerr, Chiara Pedicone, Jun Nagai, Eleanor Hollers, Daniel Dwyer, Mariana Castells
J Immunol. 2023 Mar 15; 210(6): 709–720. Published online 2023 Mar 15. doi: 10.4049/jimmunol.2100485
PMCID:
PMC9986054
AbstractArticlePDF–2.3M
8.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
9.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
10.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
11.
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα
Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz
iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686
PMCID:
PMC8220391
AbstractArticlePDF–4.4M
12.
Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia
Veronika Ecker, Martina Stumpf, Lisa Brandmeier, Tanja Neumayer, Lisa Pfeuffer, Thomas Engleitner, Ingo Ringshausen, Nina Nelson, Manfred Jücker, Stefan Wanninger, Thorsten Zenz, Clemens Wendtner, Katrin Manske, Katja Steiger, Roland Rad, Markus Müschen, Jürgen Ruland, Maike Buchner
Nat Commun. 2021; 12: 3526. Published online 2021 Jun 10. doi: 10.1038/s41467-021-23752-2
PMCID:
PMC8192787
AbstractArticlePDF–2.4M
13.
INPP5D expression is associated with risk for Alzheimer’s disease and induced by plaque-associated microglia
Andy P. Tsai, Lin Peter Bor-Chian, Chuanpeng Dong, Miguel Moutinho, Brad T. Casali, Yunlong Liu, Bruce T. Lamb, Gary E. Landreth, Adrian L. Oblak, Kwangsik Nho
Neurobiol Dis. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Neurobiol Dis. 2021 Jun; 153: 105303. Published online 2021 Feb 22. doi: 10.1016/j.nbd.2021.105303
PMCID:
PMC8082515
AbstractArticlePDF–1.5M
14.
SHIP-1, a Target of miR-155, Regulates Endothelial Cell Responses in Lung Fibrosis
Haiying Tang, Jingwei Mao, Xujun Ye, Fengrui Zhang, William G. Kerr, Tao Zheng, Zhou Zhu
FASEB J. Author manuscript; available in PMC 2021 Feb 1.
Published in final edited form as: FASEB J. 2020 Feb; 34(2): 2011–2023. Published online 2019 Dec 12. doi: 10.1096/fj.201902063R
PMCID:
PMC7449602
AbstractArticlePDF–3.2M
15.
Human Cytomegalovirus Mediates Unique Monocyte-to-Macrophage Differentiation through the PI3K/SHIP1/Akt Signaling Network
Olesea Cojohari, Jamil Mahmud, Aaron M. Altman, Megan A. Peppenelli, Michael J. Miller, Gary C. Chan
Viruses. 2020 Jun; 12(6): 652. Published online 2020 Jun 17. doi: 10.3390/v12060652
PMCID:
PMC7354488
AbstractArticlePDF–3.2M
16.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
17.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
18.
Targeted genetic analysis of cerebral blood flow imaging phenotypes implicates the INPP5D gene
Xiaohui Yao, Shannon L. Risacher, Kwangsik Nho, Andrew J. Saykin, Ze Wang, Li Shen
Neurobiol Aging. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Neurobiol Aging. 2019 Sep; 81: 213–221. Published online 2019 Jun 18. doi: 10.1016/j.neurobiolaging.2019.06.003
PMCID:
PMC6732252
AbstractArticlePDF–1.4M
19.
MARK3-mediated phosphorylation of ARHGEF2 couples the actin and tubulin cytoskeletons to establish cell polarity
María-José Sandí, Christopher B. Marshall, Marc Balan, Étienne Coyaud, Ming Zhou, Daniel M. Monson, Noboru Ishiyama, Arun A. Chandrakumar, José La Rose, Amber L. Couzens, Anne-Claude Gingras, Brian Raught, Wei Xu, Mitsuhiko Ikura, Deborah K. Morrison, Robert Rottapel
Sci Signal. Author manuscript; available in PMC 2019 May 7.
Published in final edited form as: Sci Signal. 2017 Oct 31; 10(503): eaan3286. Published online 2017 Oct 31. doi: 10.1126/scisignal.aan3286
PMCID:
PMC6504561
AbstractArticlePDF–3.6M
20.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M

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