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Items: 1 to 20 of 201

1.
Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradation
Alexander M. Pham, Hyun Jin Kwun
mBio. 2024 Aug; 15(8): e01117-24. Published online 2024 Jun 28. doi: 10.1128/mbio.01117-24
PMCID:
PMC11323502
AbstractArticlePDF–1.5M
2.
A specific phosphorylation-dependent conformational switch in SARS-CoV-2 nucleocapsid protein inhibits RNA binding
Maiia Botova, Aldo R. Camacho-Zarco, Jacqueline Tognetti, Luiza Mamigonian Bessa, Serafima Guseva, Emmi Mikkola, Nicola Salvi, Damien Maurin, Torsten Herrmann, Martin Blackledge
Sci Adv. 2024 Aug 2; 10(31): eaax2323. Published online 2024 Aug 2. doi: 10.1126/sciadv.aax2323
PMCID:
PMC11296341
AbstractArticlePDF–5.4M
3.
Substrate displacement of CK1 C-termini regulates kinase specificity
Sierra N. Cullati, Kazutoshi Akizuki, Jun-Song Chen, Jared L. Johnson, Tomer M. Yaron-Barir, Lewis C. Cantley, Kathleen L. Gould
Sci Adv. 2024 May 10; 10(19): eadj5185. Published online 2024 May 10. doi: 10.1126/sciadv.adj5185
PMCID:
PMC11086627
AbstractArticlePDF–2.4M
4.
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication
Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton
Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012
PMCID:
PMC10990277
AbstractArticlePDF–3.9M
5.
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation
Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett
Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4
PMCID:
PMC10869800
AbstractArticlePDF–9.3M
6.
Casein Kinase 1 Phosphomimetic Mutations Negatively Impact Connexin-43 Gap Junctions in Human Pluripotent Stem Cell-Derived Cardiomyocytes
Rasha Al-attar, Joseph Jargstorf, Rocco Romagnuolo, Mariam Jouni, Faisal J. Alibhai, Paul D. Lampe, Joell L. Solan, Michael A. Laflamme
Biomolecules. 2024 Jan; 14(1): 61. Published online 2024 Jan 2. doi: 10.3390/biom14010061
PMCID:
PMC10813327
AbstractArticlePDF–7.4M
7.
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines
Gisele Nishiguchi, Lauren G. Mascibroda, Sarah M. Young, Elizabeth A. Caine, Sherif Abdelhamed, Jeffrey J. Kooijman, Darcie J. Miller, Sourav Das, Kevin McGowan, Anand Mayasundari, Zhe Shi, Juan M. Barajas, Ryan Hiltenbrand, Anup Aggarwal, Yunchao Chang, Vibhor Mishra, Shilpa Narina, Melvin Thomas, Allister J. Loughran, Ravi Kalathur, Kaiwen Yu, Suiping Zhou, Xusheng Wang, Anthony A. High, Junmin Peng, Shondra M. Pruett-Miller, Danette L. Daniels, Marjeta Urh, Anang A. Shelat, Charles G. Mullighan, Kristin M. Riching, Guido J. R. Zaman, Marcus Fischer, Jeffery M. Klco, Zoran Rankovic
Nat Commun. 2024; 15: 482. Published online 2024 Jan 16. doi: 10.1038/s41467-024-44698-1
PMCID:
PMC10791743
AbstractArticlePDF–2.3M
8.
The CUL4B‐based E3 ubiquitin ligase regulates mitosis and brain development by recruiting phospho‐specific DCAFs
Anna Stier, Samuel Gilberto, Weaam I Mohamed, Lars N Royall, Jonne Helenius, Ivan Mikicic, Tatjana Sajic, Petra Beli, Daniel J Müller, Sebastian Jessberger, Matthias Peter
EMBO J. 2023 Sep; 42(17): e112847. Published online 2023 Jun 27. doi: 10.15252/embj.2022112847
PMCID:
PMC10476281
AbstractArticlePDF–2.6M
9.
Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification
Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt
J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706
PMCID:
PMC10243116
AbstractArticlePDF–13M
10.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
11.
TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN
Kaini Zhang, Chen Yang, Xin Zhou, Jin Liang, Jianjin Guo, Min Li, Yi Zhang, Shulin Shao, Peng Sun, Kai Li, Jingjing Huang, Fang Chen, Xiubin Liang, Dongming Su
Cell Mol Life Sci. 2023 Jun; 80(6): 168. Published online 2023 May 30. doi: 10.1007/s00018-023-04820-w
PMCID:
PMC10229743
AbstractArticlePDF–2.9M
12.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
13.
A kinome-wide CRISPR screen identifies CK1α as a target to overcome enzalutamide resistance of prostate cancer
Jinghui Liu, Yue Zhao, Daheng He, Katelyn M. Jones, Shan Tang, Derek B. Allison, Yanquan Zhang, Jing Chen, Qiongsi Zhang, Xinyi Wang, Chaohao Li, Chi Wang, Lang Li, Xiaoqi Liu
Cell Rep Med. 2023 Apr 18; 4(4): 101015. Published online 2023 Apr 18. doi: 10.1016/j.xcrm.2023.101015
PMCID:
PMC10140619
AbstractArticlePDF–6.5M
14.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
15.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
16.
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li
Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x
PMCID:
PMC9950447
AbstractArticlePDF–8.4M
17.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M
18.
TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
PMCID:
PMC9797988
AbstractArticlePDF–6.9M
19.
CK1α upregulates the IFNAR1 expression to prompt the anti-HBV effect of type I IFN in hepatoma carcinoma cells
Jing Xiong, Yanjun Jiang, Jinru Zhang, Yanmeng Chen, Yuan Hu
Virol Sin. 2022 Dec; 37(6): 894–903. Published online 2022 Aug 17. doi: 10.1016/j.virs.2022.08.004
PMCID:
PMC9797371
AbstractArticlePDF–2.4M
20.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M

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