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Select item 86397351.

Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing

Kentaro Mochizuki, Jafar Sharif, Kenjiro Shirane, Kousuke Uranishi, Aaron B. Bogutz, Sanne M. Janssen, Ayumu Suzuki, Akihiko Okuda, Haruhiko Koseki, Matthew C. Lorincz

Nat Commun. 2021; 12: 7020. Published online 2021 Dec 2. doi: 10.1038/s41467-021-27345-x

PMCID:: PMC8639735

Abstract Article PDF–3.5M

Select item 85641172.

Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons

Remi Akagawa, Yo-ichi Nabeshima, Takeshi Kawauchi

Front Cell Dev Biol. 2021; 9: 753175. Published online 2021 Oct 20. doi: 10.3389/fcell.2021.753175

PMCID:: PMC8564117

Abstract Article PDF–2.2M

Select item 81959993.

E2F6 initiates stable epigenetic silencing of germline genes during embryonic development

Thomas Dahlet, Matthias Truss, Ute Frede, Hala Al Adhami, Anaïs F. Bardet, Michael Dumas, Judith Vallet, Johana Chicher, Philippe Hammann, Sarah Kottnik, Peter Hansen, Uschi Luz, Gonzalo Alvarez, Ghislain Auclair, Jochen Hecht, Peter N. Robinson, Christian Hagemeier, Michael Weber

Nat Commun. 2021; 12: 3582. Published online 2021 Jun 11. doi: 10.1038/s41467-021-23596-w

PMCID:: PMC8195999

Abstract Article PDF–1.9M

Select item 57750494.

Contrasting effects of an Mdm2 functional polymorphism on tumor phenotypes

Guadalupe J. Ortiz, Yanjie Li, Sean M. Post, Vinod Pant, Shunbin Xiong, Connie A. Larsson, Adel K El-Naggar, David G. Johnson, Guillermina Lozano

Oncogene. Author manuscript; available in PMC 2018 Jan 19.

Published in final edited form as: Oncogene. 2018 Jan 18; 37(3): 332–340. Published online 2017 Sep 18. doi: 10.1038/onc.2017.344

PMCID:: PMC5775049

Abstract Article PDF–1.7M

Select item 43195595.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 38837906.

E2f6-mediated repression of the meiotic Stag3 and Smc1β genes during early embryonic development requires Ezh2 and not the de novo methyltransferase Dnmt3b

Milena Leseva, Katherine E Santostefano, Amy L Rosenbluth, Takashi Hamazaki, Naohiro Terada

Epigenetics. 2013 Aug 1; 8(8): 873–884. Published online 2013 Jul 2. doi: 10.4161/epi.25522

PMCID:: PMC3883790

Abstract Article PDF–3.1M

Select item 36474567.

The Polycomb Group Protein L3mbtl2 Assembles an Atypical PRC1-Family Complex that Is Essential in Pluripotent Stem Cells and Early Development

Jinzhong Qin, Warren A. Whyte, Endre Anderssen, Effie Apostolou, Hsu-Hsin Chen, Schahram Akbarian, Roderick T. Bronson, Konrad Hochedlinger, Sridhar Ramaswamy, Richard A. Young, Hanno Hock

Cell Stem Cell. Author manuscript; available in PMC 2013 May 8.

Published in final edited form as: Cell Stem Cell. 2012 Sep 7; 11(3): 319–332. Published online 2012 Jul 5. doi: 10.1016/j.stem.2012.06.002

PMCID:: PMC3647456

Abstract Article PDF–5.1M

Select item 34398458.

A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract

Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith

Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130

PMCID:: PMC3439845

Abstract Article PDF–1.4M

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311015110.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

Select item 304042111.

Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling

Gordon R. O. Campbell, Ariane Baudhuin, Karen Vranizan, John Ngai

Mol Cell Neurosci. Author manuscript; available in PMC 2012 Feb 1.

Published in final edited form as: Mol Cell Neurosci. 2011 Feb; 46(2): 548–561. Published online 2010 Dec 29. doi: 10.1016/j.mcn.2010.12.012

PMCID:: PMC3040421

Abstract Article PDF–6.4M

Select item 288904512.

Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues

Guillaume Velasco, Florent Hubé, Jérôme Rollin, Damien Neuillet, Cathy Philippe, Haniaa Bouzinba-Segard, Angélique Galvani, Evani Viegas-Péquignot, Claire Francastel

Proc Natl Acad Sci U S A. 2010 May 18; 107(20): 9281–9286. Published online 2010 May 3. doi: 10.1073/pnas.1000473107

PMCID:: PMC2889045

Abstract Article PDF–549K

Select item 277551813.

A Genome-Wide Screen for Spatially Restricted Expression Patterns Identifies Transcription Factors That Regulate Glial Development

Hui Fu, Jun Cai, Hans Clevers, Eva Fast, Susan Gray, Rachel Greenberg, Mukesh K. Jain, Qiufu Ma, Mengsheng Qiu, David H. Rowitch, Christopher M. Taylor, Charles D. Stiles

J Neurosci. 2009 Sep 9; 29(36): 11399–11408. doi: 10.1523/JNEUROSCI.0160-09.2009

PMCID:: PMC2775518

Abstract Article PDF–2.5M

Select item 274286214.

EKLF/KLF1 Controls Cell Cycle Entry via Direct Regulation of E2f2

Michael R. Tallack, Janelle R. Keys, Patrick O. Humbert, Andrew C. Perkins

J Biol Chem. 2009 Jul 31; 284(31): 20966–20974. Published online 2009 May 20. doi: 10.1074/jbc.M109.006346

PMCID:: PMC2742862

Abstract Article PDF–1.9M

Select item 271500215.

A Conserved E2F6-Binding Element in Murine Meiosis-Specific Gene Promoters

Sarah M. Kehoe, Masahiro Oka, Katherine E. Hankowski, Nina Reichert, Sandra Garcia, John R. McCarrey, Stefan Gaubatz, Naohiro Terada

Biol Reprod. 2008 Nov; 79(5): 921–930. Prepublished online 2008 Jul 30. doi: 10.1095/biolreprod.108.067645

PMCID:: PMC2715002

Abstract Article PDF–887K

Select item 269703616.

E2f6 and Bmi1 cooperate in axial skeletal development

Maria Courel, Laurie Friesenhahn, Jacqueline A. Lees

Dev Dyn. Author manuscript; available in PMC 2009 Jun 16.

Published in final edited form as: Dev Dyn. 2008 May; 237(5): 1232–1242. doi: 10.1002/dvdy.21516

PMCID:: PMC2697036

Abstract Article PDF–2.5M

Select item 269199617.

PHC3, a component of the hPRC-H complex, associates with E2F6 during G₀ and is lost in osteosarcoma tumors

Amit M. Deshpande, Jennifer D. Akunowicz, Xavier T. Reveles, Bina B. Patel, Elizabeth A. Saria, Richard G. Gorlick, Susan L. Naylor, Robin J. Leach, Marc F. Hansen

Oncogene. Author manuscript; available in PMC 2009 Jun 8.

Published in final edited form as: Oncogene. 2007 Mar 15; 26(12): 1714–1722. Published online 2006 Sep 25. doi: 10.1038/sj.onc.1209988

PMCID:: PMC2691996

Abstract Article PDF–2.6M

Select item 175990318.

Rb is critical in a mammalian tissue stem cell population

Pamela L. Wenzel, Lizhao Wu, Alain de Bruin, Jean-Leon Chong, Wen-Yi Chen, Geoffrey Dureska, Emily Sites, Tony Pan, Ashish Sharma, Kun Huang, Randall Ridgway, Kishore Mosaliganti, Richard Sharp, Raghu Machiraju, Joel Saltz, Hideyuki Yamamoto, James C. Cross, Michael L. Robinson, Gustavo Leone

Genes Dev. 2007 Jan 1; 21(1): 85–97. doi: 10.1101/gad.1485307

PMCID:: PMC1759903

Abstract Article PDF–1.7M

Select item 108419519.

Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6

Jörg Storre, Hans-Peter Elsässer, Miriam Fuchs, Diana Ullmann, David M. Livingston, Stefan Gaubatz

EMBO Rep. 2002 Jul 15; 3(7): 695–700. doi: 10.1093/embo-reports/kvf141

PMCID:: PMC1084195

Abstract Article PDF–454K

Select item 53465420.

A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription

Paloma H. Giangrande, Wencheng Zhu, Susanne Schlisio, Xin Sun, Seiichi Mori, Stefan Gaubatz, Joseph R. Nevins

Genes Dev. 2004 Dec 1; 18(23): 2941–2951. doi: 10.1101/gad.1239304

PMCID:: PMC534654

Abstract Article PDF–349K

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