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Select item 108218831.

The podocytes’ inflammatory responses in experimental GN are independent of canonical MYD88-dependent toll-like receptor signaling

Thomas Schömig, Paul Diefenhardt, Ingo Plagmann, Bastian Trinsch, Tim Merz, Giuliano Crispatzu, David Unnersjö-Jess, Jasper Nies, David Pütz, Claudio Sierra Gonzalez, Bernhard Schermer, Thomas Benzing, Paul Thomas Brinkkoetter, Sebastian Brähler

Sci Rep. 2024; 14: 2292. Published online 2024 Jan 27. doi: 10.1038/s41598-024-52565-8

PMCID:: PMC10821883

Abstract Article PDF–4.8M

Select item 102620542.

Mapping of the podocin proximity-dependent proteome reveals novel components of the kidney podocyte foot process

Gary F. Gerlach, Zachary H. Imseis, Shamus L. Cooper, Anabella N. Santos, Lori L. O’Brien

Front Cell Dev Biol. 2023; 11: 1195037. Published online 2023 May 30. doi: 10.3389/fcell.2023.1195037

PMCID:: PMC10262054

Abstract Article PDF–4.9M

Select item 98700893.

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis

Sudhir Kumar, Xueping Fan, Hila Milo Rasouly, Richa Sharma, David J. Salant, Weining Lu

JCI Insight. 2023 Jan 10; 8(1): e158418. Published online 2023 Jan 10. doi: 10.1172/jci.insight.158418

PMCID:: PMC9870089

Abstract Article PDF–8.1M

Select item 92329754.

Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency

Nan Guan, Hanako Kobayashi, Ken Ishii, Olena Davidoff, Feng Sha, Talat A. Ikizler, Chuan-Ming Hao, Navdeep S. Chandel, Volker H. Haase

Kidney Int. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Kidney Int. 2022 Jul; 102(1): 108–120. Published online 2022 Mar 24. doi: 10.1016/j.kint.2022.02.030

PMCID:: PMC9232975

Abstract Article PDF–1.7M

Select item 76810115.

Proteolytic cleavage of Podocin by Matriptase exacerbates podocyte injury

Shota Ozawa, Masaya Matsubayashi, Hitoki Nanaura, Motoko Yanagita, Kiyoshi Mori, Katsuhiko Asanuma, Nobuyuki Kajiwara, Kazuyuki Hayashi, Hiroshi Ohashi, Masato Kasahara, Hideki Yokoi, Hiroaki Kataoka, Eiichiro Mori, Takahiko Nakagawa

J Biol Chem. 2020 Nov 20; 295(47): 16002–16012. Published online 2020 Sep 9. doi: 10.1074/jbc.RA120.013721

PMCID:: PMC7681011

Abstract Article PDF–2.6M

Select item 72943306.

Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin

Qidong Ren, Kathrin Weyer, Youssef Rbaibi, Kimberly R. Long, Roderick J. Tan, Rikke Nielsen, Erik I. Christensen, Catherine J. Baty, Ossama B. Kashlan, Ora A. Weisz

Am J Physiol Renal Physiol. 2020 May 1; 318(5): F1284–F1294. Published online 2020 Mar 23. doi: 10.1152/ajprenal.00030.2020

PMCID:: PMC7294330

Abstract Article

Select item 72869187.

Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease

Ido Refaeli, Michael R. Hughes, Alvin Ka-Wai Wong, Mei Lin Z. Bissonnette, Calvin D. Roskelley, A. Wayne Vogl, Sean J. Barbour, Benjamin S. Freedman, Kelly M. McNagny

Sci Rep. 2020; 10: 9419. Published online 2020 Jun 10. doi: 10.1038/s41598-020-64907-3

PMCID:: PMC7286918

Abstract Article PDF–8.6M

Select item 67875688.

Cathepsin B increases ENaC activity leading to hypertension early in nephrotic syndrome

Alexey Larionov, Eileen Dahlke, Madlen Kunke, Luis Zanon Rodriguez, Ina M. Schiessl, Jean‐Luc Magnin, Ursula Kern, Abdel A. Alli, Geraldine Mollet, Oliver Schilling, Hayo Castrop, Franziska Theilig

J Cell Mol Med. 2019 Oct; 23(10): 6543–6553. Published online 2019 Jul 31. doi: 10.1111/jcmm.14387

PMCID:: PMC6787568

Abstract Article PDF–1.3M

Select item 65030199.

Foxc2 is essential for podocyte function

Daniel Nilsson, Mikael Heglind, Zahra Arani, Sven Enerbäck

Physiol Rep. 2019 May; 7(9): e14083. Published online 2019 May 6. doi: 10.14814/phy2.14083

PMCID:: PMC6503019

Abstract Article PDF–15M

Select item 635615710.

TFEB controls vascular development by regulating the proliferation of endothelial cells

Gabriella Doronzo, Elena Astanina, Davide Corà, Giulia Chiabotto, Valentina Comunanza, Alessio Noghero, Francesco Neri, Alberto Puliafito, Luca Primo, Carmine Spampanato, Carmine Settembre, Andrea Ballabio, Giovanni Camussi, Salvatore Oliviero, Federico Bussolino

EMBO J. 2019 Feb 1; 38(3): e98250. Published online 2018 Dec 27. doi: 10.15252/embj.201798250

PMCID:: PMC6356157

Abstract Article PDF–4.2M

Select item 631760511.

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation

Nicola Wanner, Julia Vornweg, Alexander Combes, Sean Wilson, Julia Plappert, Gesa Rafflenbeul, Victor G. Puelles, Raza-Ur Rahman, Timur Liwinski, Saskia Lindner, Florian Grahammer, Oliver Kretz, Mary E. Wlodek, Tania Romano, Karen M. Moritz, Melanie Boerries, Hauke Busch, Stefan Bonn, Melissa H. Little, Wibke Bechtel-Walz, Tobias B. Huber

J Am Soc Nephrol. 2019 Jan; 30(1): 63–78. Published online 2018 Dec 5. doi: 10.1681/ASN.2018070736

PMCID:: PMC6317605

Abstract Article

Select item 628786612.

Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development

Shintaro Ide, Gal Finer, Yoshiro Maezawa, Tuncer Onay, Tomokazu Souma, Rizaldy Scott, Kana Ide, Yoshihiro Akimoto, Chengjin Li, Minghao Ye, Xiangmin Zhao, Yusuke Baba, Takuya Minamizuka, Jing Jin, Minoru Takemoto, Koutaro Yokote, Susan E. Quaggin

J Am Soc Nephrol. 2018 Dec; 29(12): 2795–2808. Published online 2018 Oct 30. doi: 10.1681/ASN.2017121278

PMCID:: PMC6287866

Abstract Article

Select item 612441513.

Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome

Sierra S. Marable, Eunah Chung, Mike Adam, S. Steven Potter, Joo-Seop Park

JCI Insight. 2018 Jul 26; 3(14): e97497. Published online 2018 Jul 25. doi: 10.1172/jci.insight.97497

PMCID:: PMC6124415

Abstract Article PDF–1.2M

Select item 582760614.

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis

Nils O. Lindström, Jill A. McMahon, Jinjin Guo, Tracy Tran, Qiuyu Guo, Elisabeth Rutledge, Riana K. Parvez, Gohar Saribekyan, Robert E. Schuler, Christopher Liao, Albert D. Kim, Ahmed Abdelhalim, Seth W. Ruffins, Matthew E. Thornton, Laurence Basking, Brendan Grubbs, Carl Kesselman, Andrew P. McMahon

J Am Soc Nephrol. 2018 Mar; 29(3): 785–805. Published online 2018 Feb 15. doi: 10.1681/ASN.2017080887

PMCID:: PMC5827606

Abstract Article

Select item 579105015.

Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function

Bing Guo, Qing Lyu, Orazio J. Slivano, Ronald Dirkx, Christine K. Christie, Jan Czyzyk, Aram F. Hezel, Ali G. Gharavi, Eric M. Small, Joseph M. Miano

J Am Soc Nephrol. 2018 Feb; 29(2): 416–422. Published online 2017 Nov 7. doi: 10.1681/ASN.2017050473

PMCID:: PMC5791050

Abstract Article

Select item 576962416.

Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation

Eunah Chung, Patrick Deacon, Joo-Seop Park

Development. 2017 Dec 15; 144(24): 4530–4539. doi: 10.1242/dev.156661

PMCID:: PMC5769624

Abstract Article

Select item 567804817.

Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy

julie clar, Blandine Gri, Julien Calderaro, Marie-Christine Birling, Yann Herault, Peter Smith, Gilles Mithieux, Fabienne Rajas

Kidney Int. Author manuscript;

Published in final edited form as: Kidney Int. 2014 Oct 1; 86(4): 747–756. Published online 2014 Apr 9. doi: 10.1038/ki.2014.102

PMCID:: PMC5678048

Abstract Article

Select item 564828518.

An inducible mouse model of podocin-mutation-related nephrotic syndrome

Mansoureh Tabatabaeifar, Tanja Wlodkowski, Ivana Simic, Helga Denc, Geraldine Mollet, Stefanie Weber, John Julius Moyers, Barbara Brühl, Michael Joseph Randles, Rachel Lennon, Corinne Antignac, Franz Schaefer

PLoS One. 2017; 12(10): e0186574. Published online 2017 Oct 19. doi: 10.1371/journal.pone.0186574