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Select item 112085851.

NOS2-derived low levels of NO drive psoriasis pathogenesis

Ines Köhler, Cecilia Bivik Eding, Nada-Katarina Kasic, Deepti Verma, Charlotta Enerbäck

Cell Death Dis. 2024 Jun; 15(6): 449. Published online 2024 Jun 26. doi: 10.1038/s41419-024-06842-z

PMCID:: PMC11208585

Abstract Article PDF–5.2M

Select item 111591042.

Nitric oxide generated by iNOS reduces deformability of Lewis lung carcinoma cells

Satoshi Igawa, Izumi Hayashi, Naohiko Tanaka, Hiromi Hiruma, Masataka Majima, Tadashi Kawakami, Minoru Hirose, Noriyuki Masuda, Hirosuke Kobayashi

Cancer Sci. 2004 Apr; 95(4): 342–347. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2004.tb03213.x

PMCID:: PMC11159104

Abstract Article PDF–1.5M

Select item 111317273.

Ikaros negatively regulates inducible nitric oxide synthase expression in macrophages: Involvement of Ikaros phosphorylation by casein kinase 2

S.-J. Cho, J.-E. Huh, J. Song, D.-K. Rhee, S. Pyo

Cell Mol Life Sci. 2008 Oct; 65(20): 3290–3303. Published online 2008 Sep 27. doi: 10.1007/s00018-008-8332-7

PMCID:: PMC11131727

Abstract Article PDF–1.6M

Select item 110783964.

Impaired upper respiratory tract barrier function during postnatal development predisposes to invasive pneumococcal disease

Kristen L. Lokken-Toyli, Surya D. Aggarwal, Gavyn Chern Wei Bee, Wouter A. A. de Steenhuijsen Piters, Cindy Wu, Kenny Zhi Ming Chen, Cynthia Loomis, Debby Bogaert, Jeffrey N. Weiser

PLoS Pathog. 2024 May; 20(5): e1012111. Published online 2024 May 8. doi: 10.1371/journal.ppat.1012111

PMCID:: PMC11078396

Abstract Article PDF–3.6M

Select item 110617525.

Valosin-containing protein acts as a target and mediator of S-nitrosylation in the heart through distinct mechanisms

Xiaomeng Shi, Molly O'Connor, Hongyu Qiu

Redox Biol. 2024 Jun; 72: 103166. Published online 2024 Apr 26. doi: 10.1016/j.redox.2024.103166

PMCID:: PMC11061752

Abstract Article PDF–4.9M

Select item 110294766.

Inhibition of induced nitric oxide synthase enhances the anti-tumor effects on cancer immunotherapy using TLR7 agonist in mice

Hiroyasu Ito, Tatsuya Ando, Hideyuki Ogiso, Yuko Arioka, Mitsuru Seishima

Cancer Immunol Immunother. 2015 Apr; 64(4): 429–436. Published online 2015 Jan 8. doi: 10.1007/s00262-014-1644-6

PMCID:: PMC11029476

Abstract Article PDF–610K

Select item 109734757.

iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse

Xiao-Yu Zhao, Samantha L. Lempke, Jan C. Urbán Arroyo, Isabel G. Brown, Bocheng Yin, Magdalena M. Magaj, Nadia K. Holness, Jamison Smiley, Stefanie Redemann, Sarah E. Ewald

Nat Commun. 2024; 15: 2698. Published online 2024 Mar 27. doi: 10.1038/s41467-024-46790-y

PMCID:: PMC10973475

Abstract Article PDF–6.3M

Select item 109176608.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108974469.

Versican accumulation drives Nos2 induction and aortic disease in Marfan syndrome via Akt activation

María Jesús Ruiz-Rodríguez, Jorge Oller, Sara Martínez-Martínez, Iván Alarcón-Ruiz, Marta Toral, Yilin Sun, Ángel Colmenar, María José Méndez-Olivares, Dolores López-Maderuelo, Christine B Kern, J Francisco Nistal, Arturo Evangelista, Gisela Teixido-Tura, Miguel R Campanero, Juan Miguel Redondo

EMBO Mol Med. 2024 Jan; 16(1): 132–157. Published online 2024 Jan 2. doi: 10.1038/s44321-023-00009-7

PMCID:: PMC10897446

Abstract Article PDF–14M

Select item 1075043710.

Inducible nitric oxide synthase accelerates nonalcoholic fatty liver disease progression by regulating macrophage autophagy

Guiyuan Jin, Xiaoying Yao, Dong Liu, Juan Zhang, Xiaobei Zhang, Yonghong Yang, Yanzhen Bi, Hui Zhang, Guanjun Dong, Huixin Tang, Shumin Cheng, Feng Hong, Meng Si

Immun Inflamm Dis. 2023 Dec; 11(12): e1114. Published online 2023 Dec 26. doi: 10.1002/iid3.1114

PMCID:: PMC10750437

Abstract Article PDF–6.7M

Select item 1067591711.

Paneth cell-derived iNOS is required to maintain homeostasis in the intestinal stem cell niche

Lingxiao Huang, Zhenni Xu, Xudan Lei, Yujun Huang, Siyu Tu, Lu Xu, Jieying Xia, Dengqun Liu

J Transl Med. 2023; 21: 852. Published online 2023 Nov 25. doi: 10.1186/s12967-023-04744-w

PMCID:: PMC10675917

Abstract Article PDF–6.8M

Select item 1063769912.

The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model

Hui Zhao, Ronald J. Wong, David K. Stevenson

PLoS One. 2023; 18(11): e0294185. Published online 2023 Nov 10. doi: 10.1371/journal.pone.0294185

PMCID:: PMC10637699

Abstract Article PDF–3.6M

Select item 1059045313.

An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2

Carissa K. Harvest, Taylor J. Abele, Chen Yu, Cole J. Beatty, Megan E. Amason, Zachary P. Billman, Morgan A. DePrizio, Fernando W. Souza, Carolyn A. Lacey, Vivien I. Maltez, Heather N. Larson, Benjamin D. McGlaughon, Daniel R. Saban, Stephanie A. Montgomery, Edward A. Miao

Nat Commun. 2023; 14: 6686. Published online 2023 Oct 21. doi: 10.1038/s41467-023-42218-1

PMCID:: PMC10590453

Abstract Article PDF–14M

Select item 1040585514.

iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway

Yongzheng Guo, Yuehua You, Fei-Fei Shang, Xiaowen Wang, Bi Huang, Boying Zhao, Dingyi Lv, Shenglan Yang, Ming Xie, Lingwen Kong, Dingyuan Du, Suxin Luo, Xin Tian, Yong Xia

Theranostics. 2023; 13(12): 4229–4246. Published online 2023 Jul 24. doi: 10.7150/thno.84049

PMCID:: PMC10405855

Abstract Article PDF–12M

Select item 1003969015.

Inducible nitric oxide synthase deficiency promotes murine-β-coronavirus induced demyelination

Mithila Kamble, Fareeha Saadi, Saurav Kumar, Bhaskar Saha, Jayasri Das Sarma

Virol J. 2023; 20: 51. Published online 2023 Mar 25. doi: 10.1186/s12985-023-02006-1

PMCID:: PMC10039690

Abstract Article PDF–8.1M

Select item 1000927816.

Elevated iNOS and 3′-nitrotyrosine in Kaposi's Sarcoma tumors and mouse model

Olga Vladimirova, Samantha Soldan, Chenhe Su, Andrew Kossenkov, Owen Ngalamika, For Yue Tso, John T. West, Charles Wood, Paul M. Lieberman

Tumour Virus Res. 2023 Jun; 15: 200259. Published online 2023 Mar 1. doi: 10.1016/j.tvr.2023.200259

PMCID:: PMC10009278

Abstract Article PDF–7.1M

Select item 984161217.

Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy

Jieun Kim, Jung-Youn Han, Yujeong Lee, Kipom Kim, Young Pyo Choi, Sehyun Chae, Hyang-Sook Hoe

Mol Brain. 2023; 16: 7. Published online 2023 Jan 16. doi: 10.1186/s13041-023-00996-1

PMCID:: PMC9841612

Abstract Article PDF–4.7M

Select item 981876518.

iNOS Deletion in Alveolar Epithelium Cannot Reverse the Elastase-Induced Emphysema in Mice

Marija Gredic, Vinita Sharma, Stefan Hadzic, Cheng-Yu Wu, Oleg Pak, Baktybek Kojonazarov, Julia Duerr, Marcus A. Mall, Andreas Guenther, Ralph T. Schermuly, Friedrich Grimminger, Werner Seeger, Simone Kraut, Natascha Sommer, Norbert Weissmann

Cells. 2023 Jan; 12(1): 125. Published online 2022 Dec 28. doi: 10.3390/cells12010125

PMCID:: PMC9818765

Abstract Article PDF–2.8M

Select item 981377319.

LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages

Zheng Wei, Joonseok Oh, Richard A Flavell, Jason M. Crawford

Nature. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Nature. 2022 Sep; 609(7926): 348–353. Published online 2022 Aug 17. doi: 10.1038/s41586-022-05111-3

Correction in:: Nature. 2023 May 25

PMCID:: PMC9813773

Abstract Article PDF–2.6M

Select item 981132820.

iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation

Yongzheng Guo, Junjie Wen, An He, Can Qu, Yuce Peng, Suxin Luo, Xiaowen Wang

J Adv Res. 2023 Jan; 43: 175–186. Published online 2022 Mar 5. doi: 10.1016/j.jare.2022.03.003

PMCID:: PMC9811328

Abstract Article PDF–3.6M

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