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Select item 112428641.

Skeletal Muscle UCHL1 Negatively Regulates Muscle Development and Recovery after Muscle Injury

Ryan Antony, Katherine Aby, Morgan Montgomery, Yifan Li

Int J Mol Sci. 2024 Jul; 25(13): 7330. Published online 2024 Jul 4. doi: 10.3390/ijms25137330

PMCID:: PMC11242864

Abstract Article PDF–5.6M

Select item 109735252.

A novel proteomic signature of osteoclast differentiation unveils the deubiquitinase UCHL1 as a necessary osteoclastogenic driver

Maria Materozzi, Massimo Resnati, Cecilia Facchi, Matteo Trudu, Ugo Orfanelli, Tommaso Perini, Luigi Gennari, Enrico Milan, Simone Cenci

Sci Rep. 2024; 14: 7290. Published online 2024 Mar 27. doi: 10.1038/s41598-024-57898-y

PMCID:: PMC10973525

Abstract Article PDF–8.3M

Select item 109377943.

Deubiquitinase UCHL1 promotes angiogenesis and blood–spinal cord barrier function recovery after spinal cord injury by stabilizing Sox17

Jiaxing Wang, Chengyue Ji, Wu Ye, Yuluo Rong, Xuhui Ge, Zhuanghui Wang, Pengyu Tang, Zheng Zhou, Yongjun Luo, Weihua Cai

Cell Mol Life Sci. 2024 Dec; 81(1): 137. Published online 2024 Mar 13. doi: 10.1007/s00018-024-05186-3

PMCID:: PMC10937794

Abstract Article PDF–5.3M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107845245.

Diabetic sensory neuropathy and insulin resistance are induced by loss of UCHL1 in Drosophila

Daewon Lee, Eunju Yoon, Su Jin Ham, Kunwoo Lee, Hansaem Jang, Daihn Woo, Da Hyun Lee, Sehyeon Kim, Sekyu Choi, Jongkyeong Chung

Nat Commun. 2024; 15: 468. Published online 2024 Jan 11. doi: 10.1038/s41467-024-44747-9

PMCID:: PMC10784524

Abstract Article PDF–4.8M

Select item 106916566.

A developmental atlas of somatosensory diversification and maturation in the dorsal root ganglia by single-cell mass cytometry

Austin B. Keeler, Amy L. Van Deusen, Irene C. Gadani, Corey M. Williams, Sarah M Goggin, Ashley K. Hirt, Shayla A. Vradenburgh, Kristen I. Fread, Emily A. Puleo, Lucy Jin, O. Yipkin Calhan, Christopher D. Deppmann, Eli R. Zunder

Nat Neurosci. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Nat Neurosci. 2022 Nov; 25(11): 1543–1558. Published online 2022 Oct 27. doi: 10.1038/s41593-022-01181-8

PMCID:: PMC10691656

Abstract Article PDF–8.2M

Select item 105721877.

UCHL1 Regulates Radiation Lung Injury via Sphingosine Kinase-1

Yulia Epshtein, Biji Mathew, Weiguo Chen, Jeffrey R. Jacobson

Cells. 2023 Oct; 12(19): 2405. Published online 2023 Oct 5. doi: 10.3390/cells12192405

PMCID:: PMC10572187

Abstract Article PDF–2.4M

Select item 101978898.

The deubiquitinase UCHL1 negatively controls osteoclastogenesis by regulating TAZ/NFATC1 signalling

Zhenhua Feng, Siyue Tao, Zhaobo Huang, Bingjie Zheng, Xiangxi Kong, Yufeng Xiang, Qibin Zhang, Haixin Song, Zhikun Xu, Xiaoan Wei, Fengdong Zhao, Jian Chen

Int J Biol Sci. 2023; 19(8): 2319–2332. Published online 2023 Apr 24. doi: 10.7150/ijbs.82152

PMCID:: PMC10197889

Abstract Article PDF–7.7M

Select item 101020229.

Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

Julia Reichelt, Wiebke Sachs, Sarah Frömbling, Julia Fehlert, Maja Studencka-Turski, Anna Betz, Desiree Loreth, Lukas Blume, Susanne Witt, Sandra Pohl, Johannes Brand, Maire Czesla, Jan Knop, Bogdan I. Florea, Stephanie Zielinski, Marlies Sachs, Elion Hoxha, Irm Hermans-Borgmeyer, Gunther Zahner, Thorsten Wiech, Elke Krüger, Catherine Meyer-Schwesinger

Nat Commun. 2023; 14: 2114. Published online 2023 Apr 13. doi: 10.1038/s41467-023-37836-8

Correction in:: Nat Commun. 2023; 14: 2453.

PMCID:: PMC10102022

Abstract Article PDF–9.7M

Select item 999226710.

Role of UCHL1 in the pathogenesis of neurodegenerative diseases and brain injury

Zhiping Mi, Steven H Graham

Ageing Res Rev. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Ageing Res Rev. 2023 Apr; 86: 101856. Published online 2023 Jan 19. doi: 10.1016/j.arr.2023.101856

PMCID:: PMC9992267

Abstract Article PDF–629K

Select item 972465711.

The AAA‐ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle

Dina Aweida, Shenhav Cohen

EMBO Rep. 2022 Dec; 23(12): e55175. Published online 2022 Oct 24. doi: 10.15252/embr.202255175

PMCID:: PMC9724657

Abstract Article PDF–3.0M

Select item 960569212.

Little skate genome provides insights into genetic programs essential for limb-based locomotion

DongAhn Yoo, Junhee Park, Chul Lee, Injun Song, Young Ho Lee, Tery Yun, Hyemin Lee, Adriana Heguy, Jae Yong Han, Jeremy S Dasen, Heebal Kim, Myungin Baek

eLife. 2022; 11: e78345. Published online 2022 Oct 26. doi: 10.7554/eLife.78345

PMCID:: PMC9605692

Abstract Article PDF–8.4M

Select item 960386013.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 956689914.

In vivo visualization and molecular targeting of the cardiac conduction system

William R. Goodyer, Benjamin M. Beyersdorf, Lauren Duan, Nynke S. van den Berg, Sruthi Mantri, Francisco X. Galdos, Nazan Puluca, Jan W. Buikema, Soah Lee, Darren Salmi, Elise R. Robinson, Stephan Rogalla, Dillon P. Cogan, Chaitan Khosla, Eben L. Rosenthal, Sean M. Wu

J Clin Invest. 2022 Oct 17; 132(20): e156955. Published online 2022 Oct 17. doi: 10.1172/JCI156955