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Items: 1 to 20 of 258

1.
Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein
Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo
J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390
PMCID:
PMC11237930
AbstractArticlePDF–3.8M
2.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
3.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
4.
Dual regulation of fatty acid synthase (FASN) expression by O-GlcNAc transferase (OGT) and mTOR pathway in proliferating liver cancer cells
Sadia Raab, Alexis Gadault, Ninon Very, Amélie Decourcelle, Steffi Baldini, Céline Schulz, Marlène Mortuaire, Quentin Lemaire, Stéphan Hardivillé, Vanessa Dehennaut, Ikram El Yazidi-Belkoura, Anne-Sophie Vercoutter-Edouart, Ganna Panasyuk, Tony Lefebvre
Cell Mol Life Sci. 2021 Jul; 78(13): 5397–5413. Published online 2021 May 27. doi: 10.1007/s00018-021-03857-z
PMCID:
PMC11072354
AbstractArticlePDF–2.2M
5.
O-GlcNAc transferase regulates collagen deposition and fibrosis resolution in idiopathic pulmonary fibrosis
Shia Vang, Eric Scott Helton, Yiming Guo, Bailey Burpee, Elex Rose, Molly Easter, Seth Bollenbecker, Meghan June Hirsch, Emma Lea Matthews, Luke Isaac Jones, Patrick Henry Howze, IV, Vasanthi Rajasekaran, Rebecca Denson, Phillip Cochran, Isaac Kwame Attah, Heather Olson, Geremy Clair, Girish Melkani, Stefanie Krick, Jarrod Wesley Barnes
Front Immunol. 2024; 15: 1387197. Published online 2024 Apr 11. doi: 10.3389/fimmu.2024.1387197
PMCID:
PMC11043510
AbstractArticlePDF–4.5M
6.
Interaction network of human early embryonic transcription factors
Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0
PMCID:
PMC10933267
AbstractArticlePDF–2.9M
7.
O-GlcNAc modification of GSDMD attenuates LPS-induced endothelial cells pyroptosis
Fan Yu, Zhen Zhang, Yiping Leng, Alex F. Chen
Inflamm Res. 2024; 73(1): 5–17. Published online 2023 Nov 14. doi: 10.1007/s00011-023-01812-1
PMCID:
PMC10776498
AbstractArticlePDF–1.7M
8.
Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase
Connor M. Blankenship, Jinshan Xie, Caroline Benz, Ao Wang, Ylva Ivarsson, Jiaoyang Jiang
Nat Chem Biol. Author manuscript; available in PMC 2024 Nov 1.
Published in final edited form as: Nat Chem Biol. 2023 Nov; 19(11): 1423–1431. Published online 2023 Aug 31. doi: 10.1038/s41589-023-01422-2
PMCID:
PMC10723112
AbstractArticlePDF–3.1M
9.
Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival
Ezgi Ozyerli-Goknar, Ezgi Yagmur Kala, Ali Cenk Aksu, Ipek Bulut, Ahmet Cingöz, Sheikh Nizamuddin, Martin Biniossek, Fidan Seker-Polat, Tunc Morova, Can Aztekin, Sonia H. Y. Kung, Hamzah Syed, Nurcan Tuncbag, Mehmet Gönen, Martin Philpott, Adam P. Cribbs, Ceyda Acilan, Nathan A. Lack, Tamer T. Onder, H. T. Marc Timmers, Tugba Bagci-Onder
Cell Commun Signal. 2023; 21: 328. Published online 2023 Nov 16. doi: 10.1186/s12964-023-01335-6
PMCID:
PMC10652464
AbstractArticlePDF–8.0M
10.
Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex
Ping Lu, Yusong Liu, Maozhou He, Ting Cao, Mengquan Yang, Shutao Qi, Hongtao Yu, Haishan Gao
Nat Commun. 2023; 14: 6952. Published online 2023 Oct 31. doi: 10.1038/s41467-023-42427-8
PMCID:
PMC10618255
AbstractArticlePDF–3.1M
11.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
12.
O-GlcNAc Cycling: A Link Between Metabolism and Chronic Disease
Michelle R. Bond, John A. Hanover
Annu Rev Nutr. Author manuscript; available in PMC 2023 Sep 7.
Published in final edited form as: Annu Rev Nutr. 2013; 33: 205–229. Published online 2013 Apr 29. doi: 10.1146/annurev-nutr-071812-161240
PMCID:
PMC10483992
AbstractArticlePDF–842K
13.
Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex
Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté
J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123
PMCID:
PMC10480535
AbstractArticlePDF–2.4M
14.
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains
Julia Jülg, Dieter Edbauer, Christian Behrends
EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895
PMCID:
PMC10398660
AbstractArticlePDF–2.4M
15.
HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways
Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett
Cell Rep. Author manuscript; available in PMC 2023 Jun 19.
Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496
PMCID:
PMC10279472
AbstractArticlePDF–2.9M
16.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
17.
O‐GlcNAcylated LARP1 positively regulated by circCLNS1A facilitates hepatoblastoma progression through DKK4/β‐catenin signalling
Zhongqi Cui, Jiangtu He, Jiabei Zhu, Wenxuan Ni, Li Liu, Zhixuan Bian, Siwei Mao, Song Gu, Yuhua Shan, Zhexuan Chu, Qi Wu, Jiayi Lu, Ya Liu, Fenyong Sun, Qiuhui Pan, Yue Zhang, Nan Huang, Ji Ma
Clin Transl Med. 2023 Apr; 13(4): e1239. Published online 2023 Apr 17. doi: 10.1002/ctm2.1239
PMCID:
PMC10111636
AbstractArticlePDF–10M
18.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
19.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
20.
O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes
Yiwen CUI, Meredith CRUZ, Anna PALATNIK, Stephanie OLIVIER-VAN STICHELEN
Placenta. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Placenta. 2023 Jan; 131: 1–12. Published online 2022 Nov 19. doi: 10.1016/j.placenta.2022.11.006
PMCID:
PMC9839643
AbstractArticlePDF–1.8M

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