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Items: 1 to 20 of 489

1.
SMAD3 mediates the specification of human induced pluripotent stem cell-derived epicardium into progenitors for the cardiac pericyte lineage
Yutaro Miyoshi, Antonio Lucena-Cacace, Yu Tian, Yasuko Matsumura, Kanae Tani, Misato Nishikawa, Megumi Narita, Takeshi Kimura, Koh Ono, Yoshinori Yoshida
Stem Cell Reports. 2024 Oct 8; 19(10): 1399–1416. Published online 2024 Sep 26. doi: 10.1016/j.stemcr.2024.08.008
PMCID:
PMC11561457
AbstractArticlePDF–6.9M
2.
ZNF8 Orchestrates with Smad3 to Promote Lung Metastasis by Recruiting SMYD3 in Breast Cancer
Wenwen Geng, Junhua An, Ke Dong, Hailu Zhang, Xiuyuan Zhang, Yuchen Liu, Rong Xu, Yifan Liu, Xiaofen Huang, Haiyun Song, Wei Yan, Aihua Sun, Fuchu He, Jian Wang, Haidong Gao, Chunyan Tian
Adv Sci (Weinh) 2024 Oct; 11(40): 2404904. Published online 2024 Sep 3. doi: 10.1002/advs.202404904
PMCID:
PMC11515916
AbstractArticlePDF–23M
3.
BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma
Yuliang Feng, Liuyang Cai, Martin Pook, Feng Liu, Chao-Hui Chang, Mai Abdel Mouti, Reshma Nibhani, Stefania Militi, James Dunford, Martin Philpott, Yanbo Fan, Guo-Chang Fan, Qi Liu, Jun Qi, Cheng Wang, Wanzi Hong, Hannah Morgan, Mingyang Wang, Sakthivel Sadayappan, Anil G. Jegga, Udo Oppermann, Yigang Wang, Wei Huang, Lei Jiang, Siim Pauklin
Gastroenterology. Author manuscript; available in PMC 2024 Aug 7.
Published in final edited form as: Gastroenterology. 2024 Jan; 166(1): 139–154. Published online 2023 Sep 21. doi: 10.1053/j.gastro.2023.09.021
PMCID:
PMC11304550
AbstractArticlePDF–3.2M
4.
Functional analysis of cell lines derived from SMAD3-related Loeys-Dietz syndrome patients provides insights into genotype-phenotype relation
Nathalie P de Wagenaar, Lisa M van den Bersselaar, Hanny J H M Odijk, Sanne J M Stefens, Dieter P Reinhardt, Jolien W Roos-Hesselink, Roland Kanaar, Judith M A Verhagen, Hennie T Brüggenwirth, Ingrid M B H van de Laar, Ingrid van der Pluijm, Jeroen Essers
Hum Mol Genet. 2024 Jun 15; 33(12): 1090–1104. Published online 2024 Mar 27. doi: 10.1093/hmg/ddae044
PMCID:
PMC11153339
AbstractArticlePDF–2.4M
5.
Galectin-1 suppresses α2(I) collagen through Smad3 in renal epithelial cells
K. Okano, K. Uchida, K. Nitta, T. Hayashida
Cell Mol Life Sci. 2008 Oct; 65(20): 3304–3311. Published online 2008 Sep 15. doi: 10.1007/s00018-008-8294-9
PMCID:
PMC11131835
AbstractArticlePDF–719K
6.
Exosomes derived from adipose tissue-derived stem cells alleviated H2O2-induced oxidative stress and endothelial-to-mesenchymal transition in human umbilical vein endothelial cells by inhibition of the mir-486-3p/Sirt6/Smad signaling pathway
Yan Li, Yujie Xiao, Yage Shang, Chaolei Xu, Chao Han, Dahai Hu, Juntao Han, Hongtao Wang
Cell Biol Toxicol. 2024; 40(1): 39. Published online 2024 May 25. doi: 10.1007/s10565-024-09881-6
PMCID:
PMC11126451
AbstractArticlePDF–6.5M
7.
Calcium signaling-induced Smad3 nuclear accumulation induces acetylcholinesterase transcription in apoptotic HeLa cells
Wei Gao, Hui Zhu, Jing-Ya Zhang, Xue-Jun Zhang
Cell Mol Life Sci. 2009 Jul; 66(13): 2181–2193. Published online 2009 May 26. doi: 10.1007/s00018-009-0037-z
PMCID:
PMC11115644
AbstractArticlePDF–599K
8.
MAP4K4 and WT1 mediate SOX6‐induced cellular senescence by synergistically activating the ATF2–TGFβ2–Smad2/3 signaling pathway in cervical cancer
Han Zheng, Mingchen Liu, Shu Shi, Hongxin Huang, Xingwen Yang, Ziheng Luo, Yarong Song, Qiang Xu, Tingting Li, Lixiang Xue, Fengmin Lu, Jie Wang
Mol Oncol. 2024 May; 18(5): 1327–1346. Published online 2024 Feb 21. doi: 10.1002/1878-0261.13613
PMCID:
PMC11076992
AbstractArticlePDF–3.9M
9.
Investigating dysregulation of TGF-β1/SMAD3 signaling in atopic dermatitis: a molecular and immunohistochemical analysis
Tabasum Shafi, Roohi Rasool Wani, Showkat Hussain, Imtiyaz A Bhat, Rumana Makhdoomi, Sheikh Adil Bashir, Iffat Hassan, Zafar A Shah
Clin Exp Immunol. 2024 May; 216(2): 192–199. Published online 2023 Dec 8. doi: 10.1093/cei/uxad130
PMCID:
PMC11036103
AbstractArticlePDF–1.7M
10.
Linc00673-V3 positively regulates autophagy by promoting Smad3-mediated LC3B transcription in NSCLC
Heng Ni, Song Tang, Guang Lu, Yuequn Niu, Jinming Xu, Honghe Zhang, Jian Hu, Han-Ming Shen, Yihua Wu, Dajing Xia
Life Sci Alliance. 2024 Jun; 7(6): e202302408. Published online 2024 Mar 25. doi: 10.26508/lsa.202302408
PMCID:
PMC10963591
AbstractArticlePDF–4.4M
11.
Single-cell transcriptomic sequencing data reveal aberrant DNA methylation in SMAD3 promoter region in tumor-associated fibroblasts affecting molecular mechanism of radiosensitivity in non-small cell lung cancer
Fushi Han, Shuzhen Chen, Kangwei Zhang, Kunming Zhang, Meng Wang, Peijun Wang
J Transl Med. 2024; 22: 288. Published online 2024 Mar 16. doi: 10.1186/s12967-024-05057-2
PMCID:
PMC10944599
AbstractArticlePDF–9.9M
12.
DUSP22 Ameliorates Endothelial-to-Mesenchymal Transition in HUVECs through Smad2/3 and MAPK Signaling Pathways
Lu Chen, Hongyu Su, Zekai Tao, Cui Liang, Zhongzhao Liu, Yiming Dong, Peipei Zheng, Yuan Liu
Cardiovasc Ther. 2024; 2024: 5583961. Published online 2024 Mar 8. doi: 10.1155/2024/5583961
PMCID:
PMC10942825
AbstractArticlePDF–4.1M
13.
The Snail signaling branch downstream of the TGF-β/Smad3 pathway mediates Rho activation and subsequent stress fiber formation
Mitsuyoshi Motizuki, Takashi Yokoyama, Masao Saitoh, Keiji Miyazawa
J Biol Chem. 2024 Jan; 300(1): 105580. Published online 2023 Dec 21. doi: 10.1016/j.jbc.2023.105580
PMCID:
PMC10821601
AbstractArticlePDF–5.5M
14.
A novel pathogenic variant located just upstream of the C‐terminal Ser423‐X‐Ser425 phosphorylation motif in SMAD3 causing Loeys–Dietz syndrome
Satoshi Ishii, Takayuki Fujiwara, Hiroki Yagi, Norifumi Takeda, Masahiko Ando, Haruo Yamauchi, Ryo Inuzuka, Yuki Taniguchi, Masaru Hatano, Issei Komuro
Mol Genet Genomic Med. 2023 Dec; 11(12): e2257. Published online 2023 Oct 20. doi: 10.1002/mgg3.2257
PMCID:
PMC10724497
AbstractArticlePDF–7.6M
15.
Jagged1 intracellular domain/SMAD3 complex transcriptionally regulates TWIST1 to drive glioma invasion
Jung Yun Kim, Nayoung Hong, Sehyeon Park, Seok Won Ham, Eun-Jung Kim, Sung-Ok Kim, Junseok Jang, Yoonji Kim, Jun-Kyum Kim, Sung-Chan Kim, Jong-Whi Park, Hyunggee Kim
Cell Death Dis. 2023 Dec; 14(12): 822. Published online 2023 Dec 13. doi: 10.1038/s41419-023-06356-0
PMCID:
PMC10719344
AbstractArticlePDF–12M
16.
circEIF3I facilitates the recruitment of SMAD3 to early endosomes to promote TGF-β signalling pathway-mediated activation of MMPs in pancreatic cancer
Zhongjie Zhao, Wenbo Yang, Rui Kong, Yangyang Zhang, Le Li, Zengfu Song, Hongze Chen, Yan Luo, Tao Zhang, Chundong Cheng, Guanqun Li, Danxi Liu, Xinglong Geng, Hua Chen, Yongwei Wang, Shangha Pan, Jisheng Hu, Bei Sun
Mol Cancer. 2023; 22: 152. Published online 2023 Sep 9. doi: 10.1186/s12943-023-01847-2
PMCID:
PMC10492306
AbstractArticlePDF–16M
17.
GDF-11 downregulates placental human chorionic gonadotropin expression by activating SMAD2/3 signaling
Ze Wu, Lingling Zhang, Yuanyuan Jia, Beibei Bi, Lanlan Fang, Jung-Chien Cheng
Cell Commun Signal. 2023; 21: 179. Published online 2023 Jul 21. doi: 10.1186/s12964-023-01201-5
PMCID:
PMC10362589
AbstractArticlePDF–3.3M
18.
Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions
Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164
PMCID:
PMC10333884
AbstractArticlePDF–5.0M
19.
USP33 promotes pancreatic cancer malignant phenotype through the regulation of TGFBR2/TGFβ signaling pathway
Xinyuan Liu, Jian Xu, Bingbing shen, Jichuan Xu, Jianxin Jiang
Cell Death Dis. 2023 Jun; 14(6): 362. Published online 2023 Jun 15. doi: 10.1038/s41419-023-05871-4
PMCID:
PMC10272277
AbstractArticlePDF–9.4M
20.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M

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