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Items: 1 to 20 of 27

1.
LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages
Zheng Wei, Joonseok Oh, Richard A Flavell, Jason M. Crawford
Nature. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Nature. 2022 Sep; 609(7926): 348–353. Published online 2022 Aug 17. doi: 10.1038/s41586-022-05111-3
Correction in:
Nature. 2023 May 25
PMCID:
PMC9813773
AbstractArticlePDF–2.6M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
LACC1 deficiency links juvenile arthritis with autophagy and metabolism in macrophages
Ommar Omarjee, Anne-Laure Mathieu, Gaëlle Quiniou, Marion Moreews, Michelle Ainouze, Cécile Frachette, Isabelle Melki, Cécile Dumaine, Mathieu Gerfaud-Valentin, Agnès Duquesne, Tilmann Kallinich, Eda Tahir Turanli, Christophe Malcus, Sébastien Viel, Rémi Pescarmona, Sophie Georgin-Lavialle, Yvan Jamilloux, Jean-Paul Larbre, Guillaume Sarrabay, Flora Magnotti, Gillian I. Rice, Francoise Bleicher, Jonathan Reboulet, Samir Merabet, Thomas Henry, Yanick J. Crow, Mathias Faure, Thierry Walzer, Alexandre Belot
J Exp Med. 2021 Mar 1; 218(3): e20201006. Published online 2021 Feb 19. doi: 10.1084/jem.20201006
PMCID:
PMC7901146
AbstractArticlePDF–4.3M
4.
LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes
Chen Huang, Matija Hedl, Kishu Ranjan, Clara Abraham
Cell Rep. Author manuscript; available in PMC 2020 Jul 21.
Published in final edited form as: Cell Rep. 2019 Dec 24; 29(13): 4525–4539.e4. doi: 10.1016/j.celrep.2019.11.105
PMCID:
PMC7372507
AbstractArticlePDF–3.2M
5.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
6.
FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle
M. Zaeem Cader, Rodrigo Pereira de Almeida Rodrigues, James A. West, Gavin W. Sewell, Muhammad N. Md-Ibrahim, Stephanie Reikine, Giuseppe Sirago, Lukas W. Unger, Ana Belén Inglesias-Romero, Katharina Ramshorn, Lea-Maxie Haag, Svetlana Saveljeva, Jana-Fabienne Ebel, Philip Rosenstiel, Nicole C. Kaneider, James C. Lee, Trevor D. Lawley, Allan Bradley, Gordon Dougan, Yorgo Modis, Julian L. Griffin, Arthur Kaser
Cell. 2020 Jan 23; 180(2): 278–295.e23. doi: 10.1016/j.cell.2019.12.017
Correction in:
Cell. 2020 Feb 20; 180(4): 815.
PMCID:
PMC6978800
AbstractArticle
7.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
8.
C13orf31 (FAMIN) is a central regulator of immunometabolic function
M. Zaeem Cader, Katharina Boroviak, Qifeng Zhang, Ghazaleh Assadi, Sarah L. Kempster, Gavin W. Sewell, Svetlana Saveljeva, Jonathan W. Ashcroft, Simon Clare, Subhankar Mukhopadhyay, Karen P. Brown, Markus Tschurtschenthaler, Tim Raine, Brendan Doe, Edwin R. Chilvers, Jules L. Griffin, Nicole C. Kaneider, R. Andres Floto, Mauro D’Amato, Allan Bradley, Michael J. O. Wakelam, Gordon Dougan, Arthur Kaser
Nat Immunol. Author manuscript; available in PMC 2019 Jun 18.
Published in final edited form as: Nat Immunol. 2016 Sep 1; 17(9): 1046–1056. Published online 2016 Aug 1. doi: 10.1038/ni.3532
PMCID:
PMC6581540
AbstractArticlePDF–2.8M
9.
Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese
Dong Wang, Yu Fan, Mahadev Malhi, Rui Bi, Yong Wu, Min Xu, Xiu-Feng Yu, Heng Long, Yu-Ye Li, Deng-Feng Zhang, Yong-Gang Yao
Am J Hum Genet. 2018 May 3; 102(5): 794–805. Published online 2018 Apr 26. doi: 10.1016/j.ajhg.2018.03.006
PMCID:
PMC5986702
AbstractArticlePDF–1.6M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes
Amit Lahiri, Matija Hedl, Jie Yan, Clara Abraham
Nat Commun. 2017; 8: 15614. Published online 2017 Jun 8. doi: 10.1038/ncomms15614
PMCID:
PMC5472760
AbstractArticlePDF–1.0M
12.
Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet’s disease susceptibility
Masaki Takeuchi, Nobuhisa Mizuki, Akira Meguro, Michael J. Ombrello, Yohei Kirino, Colleen Satorius, Julie Le, Mary Blake, Burak Erer, Tatsukata Kawagoe, Duran Ustek, Ilknur Tugal-Tutkun, Emire Seyahi, Yilmaz Ozyazgan, Inês Sousa, Fereydoun Davatchi, Vânia Francisco, Farhad Shahram, Bahar Sadeghi Abdollahi, Abdolhadi Nadji, Niloofar Mojarad Shafiee, Fahmida Ghaderibarmi, Shigeaki Ohno, Atsuhisa Ueda, Yoshiaki Ishigatsubo, Massimo Gadina, Sofia A. Oliveira, Ahmet Gül, Daniel L. Kastner, Elaine F. Remmers
Nat Genet. Author manuscript; available in PMC 2017 Aug 6.
Published in final edited form as: Nat Genet. 2017 Mar; 49(3): 438–443. Published online 2017 Feb 6. doi: 10.1038/ng.3786
PMCID:
PMC5369770
AbstractArticlePDF–684K
13.
Genetic Risk for Inflammatory Bowel Disease is a Determinant of Crohn’s disease Development in Chronic Granulomatous Disease
Chengrui Huang, Suk See De Ravin, Adam R. Paul, Theo Heller, Nancy Ho, Lisa Wu Datta, Christa S. Zerbe, Beatriz E. Marciano, Douglas B. Kuhns, NIDDK IBD Genetics Consortium, Howard A. Kader, Steven M. Holland, Harry L. Malech, Steven R. Brant
Inflamm Bowel Dis. Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: Inflamm Bowel Dis. 2016 Dec; 22(12): 2794–2801. doi: 10.1097/MIB.0000000000000966
PMCID:
PMC5303573
AbstractArticlePDF–867K
14.
Functional Analyses of the Crohn’s Disease Risk Gene LACC1
Ghazaleh Assadi, Liselotte Vesterlund, Ferdinando Bonfiglio, Luca Mazzurana, Lina Cordeddu, Danika Schepis, Jenny Mjösberg, Sabrina Ruhrmann, Alessia Fabbri, Vladana Vukojevic, Piergiorgio Percipalle, Florian A. Salomons, Jurga Laurencikiene, Leif Törkvist, Jonas Halfvarson, Mauro D’Amato
PLoS One. 2016; 11(12): e0168276. Published online 2016 Dec 13. doi: 10.1371/journal.pone.0168276
PMCID:
PMC5154582
AbstractArticlePDF–2.6M
15.
Juvenile arthritis caused by a novel FAMIN (LACC1) mutation in two children with systemic and extended oligoarticular course
Tilmann Kallinich, Anne Thorwarth, Sae-Lim von Stuckrad, Angela Rösen-Wolff, Hella Luksch, Patrick Hundsdoerfer, Kirsten Minden, Peter Krawitz
Pediatr Rheumatol Online J. 2016; 14: 63. Published online 2016 Nov 24. doi: 10.1186/s12969-016-0124-2
PMCID:
PMC5122026
AbstractArticlePDF–413K
16.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle
17.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
18.
Newly Recognized Mendelian Disorders with Rheumatic Manifestations
Adriana Almeida de Jesus, Raphaela Goldbach-Mansky
Curr Opin Rheumatol. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Curr Opin Rheumatol. 2015 Sep; 27(5): 511–519. doi: 10.1097/BOR.0000000000000207
PMCID:
PMC4565793
AbstractArticlePDF–209K
19.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho
Nature. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582
PMCID:
PMC3491803
AbstractArticlePDF–706K
20.
Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci
Andre Franke, Dermot P.B. McGovern, Jeffrey C. Barrett, Kai Wang, Graham L. Radford-Smith, Tariq Ahmad, Charlie W. Lees, Tobias Balschun, James Lee, Rebecca Roberts, Carl A. Anderson, Joshua C. Bis, Suzanne Bumpstead, David Ellinghaus, Eleonora M. Festen, Michel Georges, Talin Haritunians, Luke Jostins, Anna Latiano, Christopher G. Mathew, Grant W. Montgomery, Natalie J. Prescott, Jerome I. Rotter, Philip Schumm, Yashoda Sharma, Lisa A. Simms, Kent D. Taylor, David Whiteman, Cisca Wijmenga, Robert N. Baldassano, Murray Barclay, Theodore M. Bayless, Stephan Brand, Carsten Buning, Albert Cohen, Jean-Frederick Colombel, Mario Cottone, Laura Stronati, Ted Denson, Martine De Vos, Renata D’Inca, Marla Dubinsky, Cathryn Edwards, Tim Florin, Denis Franchimont, Richard Gearry, Jürgen Glas, Andre Van Gossum, Stephen L. Guthery, Jonas Halfvarson, Daan Hommes, Jean-Pierre Hugot, Debby Laukens, Ian Lawrance, Marc Lemann, Arie Levine, Cecile Libioulle, Edouard Louis, Craig Mowat, William Newman, Julián Panés, Anne Phillips, Deborah D. Proctor, Miguel Regueiro, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, Frank Seibold, A. Hillary Steinhart, Pieter C.F. Stokkers, Leif Torkvist, Gerd Kullak Ublick, Soumya Raychaudhuri, Todd Green, Thomas Walters, Stephan R. Targan, Steven R. Brant, John D. Rioux, Mauro D’Amato, Rinse Weersma, Subra Kugathasan, Anne M. Griffiths, John C. Mansfield, Severine Vermeire, Richard H. Duerr, Mark S. Silverberg, Jack Satsangi, Stefan Schreiber, Judy H. Cho, Vito Annese, Hakon Hakonarson, Mark J. Daly, Miles Parkes
Nat Genet. Author manuscript; available in PMC 2012 Mar 12.
Published in final edited form as: Nat Genet. 2010 Dec; 42(12): 1118–1125. doi: 10.1038/ng.717
PMCID:
PMC3299551
ArticlePDF–864K

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