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Select item 108959011.

RGS6 drives cardiomyocyte death following nucleolar stress by suppressing Nucleolin/miRNA-21

Abhishek Singh Sengar, Manish Kumar, Chetna Rai, Sreemoyee Chakraborti, Dinesh Kumar, Pranesh Kumar, Sukhes Mukherjee, Kausik Mondal, Adele Stewart, Biswanath Maity

J Transl Med. 2024; 22: 204. Published online 2024 Feb 26. doi: 10.1186/s12967-024-04985-3

PMCID:: PMC10895901

Abstract Article PDF–5.3M

Select item 107693502.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 107098703.

Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice

Juan Song, Miao Li, Cuicui Chen, Jian Zhou, Linlin Wang, Yu Yan, Jun She, Lin Tong, Yuanlin Song

Cell Mol Biol Lett. 2023; 28: 102. Published online 2023 Dec 8. doi: 10.1186/s11658-023-00488-z

PMCID:: PMC10709870

Abstract Article PDF–5.6M

Select item 105044214.

RGS6 negatively regulates inhibitory G protein signaling in VTA dopamine neurons and positively regulates binge-like alcohol consumption in mice

Margot C. DeBaker, Eric H. Mitten, Timothy R. Rose, Ezequiel Marron Fernandez de Velasco, Runbo Gao, Anna M. Lee, Kevin Wickman

Br J Pharmacol. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Br J Pharmacol. 2023 Aug; 180(16): 2140–2155. Published online 2023 Apr 13. doi: 10.1111/bph.16071

PMCID:: PMC10504421

Abstract Article PDF–1.8M

Select item 90610165.

RGS6 Drives Spinal Cord Injury by Inhibiting AMPK Pathway in Mice

Wenxin Dao, Zhe Xiao, Weize Yang, Xiaomin Luo, Hongxia Xia, Zuneng Lu

Dis Markers. 2022; 2022: 4535652. Published online 2022 Apr 25. doi: 10.1155/2022/4535652

PMCID:: PMC9061016

Abstract Article PDF–1.2M

Select item 88052026.

Protein Profiling of RGS6, a Pleiotropic Gene Implicated in Numerous Neuropsychiatric Disorders, Reveals Multi-Isoformic Expression and a Novel Brain-Specific Isoform

K. E. Ahlers-Dannen, J. Yang, M. M. Spicer, B. Maity, A. Stewart, J. G. Koland, R. A. Fisher

eNeuro. 2022 Jan-Feb; 9(1): ENEURO.0379-21.2021. Prepublished online 2021 Dec 8. Published online 2022 Jan 18. doi: 10.1523/ENEURO.0379-21.2021

PMCID:: PMC8805202

Abstract Article PDF–5.7M

Select item 74505327.

RGS6 mediates effects of voluntary running on adult hippocampal neurogenesis

Yu Gao, Minjie Shen, Jose Carlos Gonzalez, Qiping Dong, Sudharsan Kannan, Johnson Hoang, Brian E. Eisinger, Jyotsna pandey, Sahar Javadi, Qiang Chang, Daifeng Wang, Linda Overstreet-Wadiche, Xinyu Zhao

Cell Rep. Author manuscript; available in PMC 2020 Aug 27.

Published in final edited form as: Cell Rep. 2020 Aug 4; 32(5): 107997. doi: 10.1016/j.celrep.2020.107997

Correction in:: Cell Rep. 2020 Aug 25; 32(8): 108114.

PMCID:: PMC7450532

Abstract Article PDF–1.6M

Select item 73220858.

GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells

Allison Anderson, Ikuo Masuho, Ezequiel Marron Fernandez de Velasco, Atsushi Nakano, Lutz Birnbaumer, Kirill A. Martemyanov, Kevin Wickman

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14522–14531. Published online 2020 Jun 8. doi: 10.1073/pnas.2001270117

PMCID:: PMC7322085

Abstract Article PDF–1.6M

Select item 66756559.

Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution

William R. Goodyer, Benjamin M. Beyersdorf, David T. Paik, Lei Tian, Guang Li, Jan W. Buikema, Orlando Chirikian, Shannon Choi, Sneha Venkatraman, Eliza L. Adams, Marc Tessier-Lavigne, Joseph C. Wu, Sean M. Wu

Circ Res. Author manuscript; available in PMC 2020 Aug 2.

Published in final edited form as: Circ Res. 2019 Aug 2; 125(4): 379–397. Published online 2019 Jul 9. doi: 10.1161/CIRCRESAHA.118.314578

PMCID:: PMC6675655

Abstract Article PDF–5.1M

Select item 662924310.

Age-dependent nigral dopaminergic neurodegeneration and α-synuclein accumulation in RGS6-deficient mice

Zili Luo, Katelin E. Ahlers-Dannen, Mackenzie M. Spicer, Jianqi Yang, Stephanie Alberico, Hanna E. Stevens, Nandakumar S. Narayanan, Rory A. Fisher

JCI Insight. 2019 Jul 11; 4(13): e126769. Published online 2019 Jul 11. doi: 10.1172/jci.insight.126769

PMCID:: PMC6629243

Abstract Article PDF–8.8M

Select item 640489711.

Regulator of G Protein Signaling 6 Facilities Cardiac Hypertrophy by Activating Apoptosis Signal–Regulating Kinase 1–P38/c‐JUN N‐Terminal Kinase 1/2 Signaling

Zhijun Huang, Jingxian Shu, Weihong Jiang, Mengqing Jiang, Yao Lu, Haijiang Dai, Nana Xu, Hong Yuan, Jingjing Cai

J Am Heart Assoc. 2018 Oct 2; 7(19): e009179. Published online 2018 Sep 25. doi: 10.1161/JAHA.118.009179

PMCID:: PMC6404897

Abstract Article PDF–3.1M

Select item 590588112.

The influences of the M₂R-GIRK4-RGS6 dependent parasympathetic pathway on electrophysiological properties of the mouse heart

Kanchan Kulkarni, Xueyi Xie, Ezequiel Marron Fernandez de Velasco, Allison Anderson, Kirill A. Martemyanov, Kevin Wickman, Elena G. Tolkacheva

PLoS One. 2018; 13(4): e0193798. Published online 2018 Apr 18. doi: 10.1371/journal.pone.0193798

Correction in:: PLoS One. 2018; 13(7): e0200553.

PMCID:: PMC5905881

Abstract Article PDF–4.0M

Select item 577535413.

Expression and relevance of the G protein-gated K⁺ channel in the mouse ventricle

Allison Anderson, Kanchan Kulkarni, Ezequiel Marron Fernandez de Velasco, Nicholas Carlblom, Zhilian Xia, Atsushi Nakano, Kirill A. Martemyanov, Elena G. Tolkacheva, Kevin Wickman

Sci Rep. 2018; 8: 1192. Published online 2018 Jan 19. doi: 10.1038/s41598-018-19719-x

PMCID:: PMC5775354

Abstract Article PDF–6.3M

Select item 572178314.

Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca²⁺/Calmodulin‐Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development

Bandana Chakravarti, Jianqi Yang, Katelin E. Ahlers‐Dannen, Zili Luo, Heather A. Flaherty, David K. Meyerholz, Mark E. Anderson, Rory A. Fisher

J Am Heart Assoc. 2017 Nov; 6(11): e007038. Published online 2017 Oct 27. doi: 10.1161/JAHA.117.007038

PMCID:: PMC5721783

Abstract Article PDF–6.6M

Select item 564508215.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 534246716.

RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation

Jianqi Yang, Lance T. Platt, Biswanath Maity, Katelin E. Ahlers, Zili Luo, Zhibo Lin, Bandana Chakravarti, Stella-Rita Ibeawuchi, Ryan W. Askeland, Jolanta Bondaruk, Bogdan A. Czerniak, Rory A. Fisher

Oncotarget. 2016 Oct 25; 7(43): 69159–69172. Published online 2016 Oct 4. doi: 10.18632/oncotarget.12473