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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104159172.

5-HT_1A and 5-HT_2B receptor interaction and co-clustering regulate serotonergic neuron excitability

Amina Benhadda, Célia Delhaye, Imane Moutkine, Xavier Marques, Marion Russeau, Corentin Le Magueresse, Anne Roumier, Sabine Lévi, Luc Maroteaux

iScience. 2023 Aug 18; 26(8): 107401. Published online 2023 Jul 15. doi: 10.1016/j.isci.2023.107401

PMCID:: PMC10415917

Abstract Article PDF–6.4M

Select item 76881603.

Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics of Notch1 heterozygous mice in a high-cholesterol diet model

J. Ethan Joll, II, Cynthia R. Clark, Christine S. Peters, Michael A. Raddatz, Matthew R. Bersi, W. David Merryman

PLoS One. 2020; 15(11): e0238407. Published online 2020 Nov 25. doi: 10.1371/journal.pone.0238407

PMCID:: PMC7688160

Abstract Article PDF–2.3M

Select item 76745264.

Sleep Deprivation Selectively Down-Regulates Astrocytic 5-HT_2B Receptors and Triggers Depressive-Like Behaviors via Stimulating P2X₇ Receptors in Mice

Maosheng Xia, Zexiong Li, Shuai Li, Shanshan Liang, Xiaowei Li, Beina Chen, Manman Zhang, Chengyi Dong, Alexei Verkhratsky, Dawei Guan, Baoman Li

Neurosci Bull. 2020 Nov; 36(11): 1259–1270. Published online 2020 Jun 6. doi: 10.1007/s12264-020-00524-4

PMCID:: PMC7674526

Abstract Article PDF–1.7M

Select item 75847525.

Improved visual discrimination learning in mice with partial 5-HT_2B gene deletion

Anna K. Radke, Patrick T. Piantadosi, George R. Uhl, F. Scott Hall, Andrew Holmes

Neurosci Lett. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Neurosci Lett. 2020 Nov 1; 738: 135378. Published online 2020 Sep 10. doi: 10.1016/j.neulet.2020.135378

PMCID:: PMC7584752

Abstract Article PDF–809K

Select item 73607336.

Bladder outlet obstruction disrupts circadian bladder function in mice

Takeya Kitta, Hiroki Chiba, Yukiko Kanno, Tsuyoshi Hattori, Madoka Higuchi, Mifuka Ouchi, Mio Togo, Yui Takahashi, Mai Michishita, Tatsuya Kitano, Nobuo Shinohara

Sci Rep. 2020; 10: 11578. Published online 2020 Jul 14. doi: 10.1038/s41598-020-68499-w

PMCID:: PMC7360733

Abstract Article PDF–1.0M

Select item 69714877.

Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation

Joon Ho Moon, Yeong Gi Kim, Kyuho Kim, Sho Osonoi, Shuang Wang, Diane C. Saunders, Juehu Wang, Katherine Yang, Hyeongseok Kim, Junguee Lee, Ji-Seon Jeong, Ronadip R. Banerjee, Seung K. Kim, Yingjie Wu, Hiroki Mizukami, Alvin C. Powers, Michael S. German, Hail Kim

Diabetes. 2020 Feb; 69(2): 205–214. Published online 2019 Dec 5. doi: 10.2337/db19-0546

PMCID:: PMC6971487

Abstract Article PDF–2.0M

Select item 67742238.

Serotonin and the 5-HT_2B Receptor in the Development of Enteric Neurons

Elena Fiorica-Howells, Luc Maroteaux, Michael D. Gershon

J Neurosci. 2000 Jan 1; 20(1): 294–305. doi: 10.1523/JNEUROSCI.20-01-00294.2000

PMCID:: PMC6774223

Abstract Article PDF–3.1M

Select item 66706699.

Serotonin 5-HT_2B Receptors Are Required for 3,4-Methylenedioxymethamphetamine-Induced Hyperlocomotion and 5-HT Release In Vivo and In Vitro

Stéphane Doly, Emmanuel Valjent, Vincent Setola, Jacques Callebert, Denis Hervé, Jean-Marie Launay, Luc Maroteaux

J Neurosci. 2008 Mar 12; 28(11): 2933–2940. doi: 10.1523/JNEUROSCI.5723-07.2008

PMCID:: PMC6670669

Abstract Article PDF–712K

Select item 659663110.

Serotonin 2B Receptors in Mesoaccumbens Dopamine Pathway Regulate Cocaine Responses

Stéphane Doly, Emily Quentin, Raphaël Eddine, Stefania Tolu, Sebastian P. Fernandez, Jesus Bertran-Gonzalez, Emmanuel Valjent, Arnauld Belmer, Xavier Viñals, Jacques Callebert, Philippe Faure, Frank J. Meye, Denis Hervé, Patricia Robledo, Manuel Mameli, Jean-Marie Launay, Rafael Maldonado, Luc Maroteaux

J Neurosci. 2017 Oct 25; 37(43): 10372–10388. doi: 10.1523/JNEUROSCI.1354-17.2017

PMCID:: PMC6596631

Abstract Article PDF–4.0M

Select item 649579611.

Amyloid beta‐derived neuroplasticity in bone marrow‐derived mesenchymal stem cells is mediated by NPY and 5‐HT2B receptors via ERK1/2 signalling pathways

H. K. Jin, J. S. Bae, S. Furuya, J. E. Carter

Cell Prolif. 2009 Oct; 42(5): 571–586. Published online 2009 Jul 13. doi: 10.1111/j.1365-2184.2009.00625.x

PMCID:: PMC6495796

Abstract Article PDF–818K

Select item 624003512.

Serotonin signals through a gut-liver axis to regulate hepatic steatosis

Wonsuk Choi, Jun Namkung, Inseon Hwang, Hyeongseok Kim, Ajin Lim, Hye Jung Park, Hye Won Lee, Kwang-Hyub Han, Seongyeol Park, Ji-Seon Jeong, Geul Bang, Young Hwan Kim, Vijay K. Yadav, Gerard Karsenty, Young Seok Ju, Chan Choi, Jae Myoung Suh, Jun Yong Park, Sangkyu Park, Hail Kim

Nat Commun. 2018; 9: 4824. Published online 2018 Nov 16. doi: 10.1038/s41467-018-07287-7

Correction in:: Nat Commun. 2019; 10: 158.

PMCID:: PMC6240035

Abstract Article PDF–1.2M

Select item 598354013.

Positive regulation of raphe serotonin neurons by serotonin 2B receptors

Arnauld Belmer, Emily Quentin, Silvina L. Diaz, Bruno P. Guiard, Sebastian P. Fernandez, Stéphane Doly, Sophie M. Banas, Pothitos M. Pitychoutis, Imane Moutkine, Aude Muzerelle, Anna Tchenio, Anne Roumier, Manuel Mameli, Luc Maroteaux

Neuropsychopharmacology. 2018 Jun; 43(7): 1623–1632. Published online 2018 Feb 5. doi: 10.1038/s41386-018-0013-0

PMCID:: PMC5983540

Abstract Article PDF–1.1M

Select item 540995514.

The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation

Corinne Collet, Corinne Schiltz, Valérie Geoffroy, Luc Maroteaux, Jean-Marie Launay, Marie-Christine De Vernejoul

FASEB J. Author manuscript;

Published in final edited form as: FASEB J. 2008 Feb; 22(2): 418–427. Published online 2007 Sep 10. doi: 10.1096/fj.07-9209com

PMCID:: PMC5409955

Abstract Article

Select item 539176315.

Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT_2C protomers

Imane Moutkine, Emily Quentin, Bruno P. Guiard, Luc Maroteaux, Stephane Doly

J Biol Chem. 2017 Apr 14; 292(15): 6352–6368. Published online 2017 Mar 3. doi: 10.1074/jbc.M117.779041

PMCID:: PMC5391763

Abstract Article PDF–3.8M

Select item 529582116.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 529484517.

5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival

Junhua Lv, Lu Wang, Ya Gao, Yu-Qiang Ding, Feng Liu

J Exp Med. 2017 Feb; 214(2): 529–545. doi: 10.1084/jem.20150906

PMCID:: PMC5294845

Abstract Article PDF–3.9M

Select item 527132918.

Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells

Luis Rodrigo Cataldo, María L. Mizgier, Roberto Bravo Sagua, Fabián Jaña, César Cárdenas, Paola Llanos, Dolores Busso, Pablo Olmos, José E. Galgani, José L. Santos, Víctor A. Cortés

PLoS One. 2017; 12(1): e0170213. Published online 2017 Jan 27. doi: 10.1371/journal.pone.0170213

PMCID:: PMC5271329

Abstract Article PDF–1.1M

Select item 474929319.

Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

James D. West, Erica J. Carrier, Nathaniel C. Bloodworth, Alison K. Schroer, Peter Chen, Larisa M. Ryzhova, Santhi Gladson, Sheila Shay, Joshua D. Hutcheson, W. David Merryman

PLoS One. 2016; 11(2): e0148657. Published online 2016 Feb 10. doi: 10.1371/journal.pone.0148657

PMCID:: PMC4749293

Abstract Article PDF–5.4M

Select item 431955920.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

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