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Items: 1 to 20 of 42

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
SCD1 inhibition enhances the effector functions of CD8+ T cells via ACAT1‐dependent reduction of esterified cholesterol
Toshihiro Sugi, Yuki Katoh, Toshikatsu Ikeda, Daichi Seta, Takashi Iwata, Hiroshi Nishio, Masaki Sugawara, Daiki Kato, Kanoko Katoh, Kei Kawana, Tomonori Yaguchi, Yutaka Kawakami, Shuichi Hirai
Cancer Sci. 2024 Jan; 115(1): 48–58. Published online 2023 Oct 25. doi: 10.1111/cas.15999
PMCID:
PMC10823278
AbstractArticlePDF–1.4M
3.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
4.
Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells
Maximillian A. Rogers, Catherine C. Y. Chang, Robert A. Maue, Elaina M. Melton, Andrew A. Peden, William S. Garver, Junghoon Lee, Peter Schroen, Mitchell Huang, Ta-Yuan Chang
Proc Natl Acad Sci U S A. 2022 May 3; 119(18): e2201646119. Published online 2022 May 4. doi: 10.1073/pnas.2201646119
PMCID:
PMC9170141
AbstractArticlePDF–2.7M
5.
A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression
Michishige Terasaki, Hironori Yashima, Yusaku Mori, Tomomi Saito, Takanori Matsui, Munenori Hiromura, Hideki Kushima, Naoya Osaka, Makoto Ohara, Tomoyasu Fukui, Tsutomu Hirano, Sho-ichi Yamagishi
Int J Mol Sci. 2020 Jul; 21(13): 4811. Published online 2020 Jul 7. doi: 10.3390/ijms21134811
PMCID:
PMC7369823
AbstractArticlePDF–991K
6.
Involvement of ABC-transporters and acyltransferase 1 in intracellular cholesterol-mediated autophagy in bovine alveolar macrophages in response to the Bacillus Calmette-Guerin (BCG) infection
Jinrui Xu, Yanbing Zhou, Yi Yang, Cuiping Lv, Xiaoming Liu, Yujiong Wang
BMC Immunol. 2020; 21: 26. Published online 2020 May 12. doi: 10.1186/s12865-020-00356-x
PMCID:
PMC7216371
AbstractArticlePDF–1.8M
7.
Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function
Yanqing Xu, Ximing Du, Nigel Turner, Andrew J. Brown, Hongyuan Yang
J Biol Chem. 2019 Dec 13; 294(50): 19306–19321. Published online 2019 Nov 14. doi: 10.1074/jbc.RA119.011160
PMCID:
PMC6916500
AbstractArticlePDF–5.8M
8.
Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells
Hisataka Yamazaki, Manabu Takahashi, Tetsuji Wakabayashi, Kent Sakai, Daisuke Yamamuro, Akihito Takei, Shoko Takei, Shuichi Nagashima, Hiroaki Yagyu, Motohiro Sekiya, Ken Ebihara, Shun Ishibashi
J Atheroscler Thromb. 2019 Mar 1; 26(3): 246–259. doi: 10.5551/jat.44040
PMCID:
PMC6402884
AbstractArticlePDF–1.4M
9.
Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells
Farzad Asadi, Savita Dhanvantari
Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792
PMCID:
PMC6346685
AbstractArticlePDF–3.6M
10.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
11.
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization
Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II
Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053
Correction in:
Proteomes. 2019 Mar; 7(1): 7.
PMCID:
PMC6313900
AbstractArticlePDF–2.5M
12.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
13.
Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity
Li-Hao Huang, Elaina M. Melton, Haibo Li, Paul Sohn, DaeYoung Jung, Ching-Yi Tsai, Tian Ma, Hiroyuki Sano, HyeKyung Ha, Randall H. Friedline, Jason K. Kim, Edward Usherwood, Catherine C. Y. Chang, Ta-Yuan Chang
Am J Physiol Endocrinol Metab. 2018 Sep 1; 315(3): E340–E356. Published online 2018 Mar 13. doi: 10.1152/ajpendo.00174.2017
PMCID:
PMC6171008
AbstractArticle
14.
In vitro exploration of ACAT contributions to lipid droplet formation during adipogenesis
Yuyan Zhu, Chih-Yu Chen, Junjie Li, Ji-Xin Cheng, Miran Jang, Kee-Hong Kim
J Lipid Res. 2018 May; 59(5): 820–829. Published online 2018 Mar 16. doi: 10.1194/jlr.M081745
PMCID:
PMC5928425
AbstractArticlePDF–1.1M
15.
QTL Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant
Qimin Hai, Brian Ritchey, Peggy Robinet, Alexander M. Alzayed, Greg Brubaker, Jinying Zhang, Jonathan D. Smith
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Jan; 38(1): 83–91. Published online 2017 Nov 2. doi: 10.1161/ATVBAHA.117.310173
PMCID:
PMC5746475
AbstractArticlePDF–1002K
16.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
17.
Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity
Tara Vanderweyde, Daniel J. Apicco, Katherine Youmans-Kidder, Peter E.A. Ash, Casey Cook, Edroaldo Lummertz da Rocha, Karen Jansen-West, Alissa A. Frame, Allison Citro, John D. Leszyk, Pavel Ivanov, Jose F. Abisambra, Martin Steffen, Hu Li, Leonard Petrucelli, Benjamin Wolozin
Cell Rep. Author manuscript; available in PMC 2017 Feb 24.
Published in final edited form as: Cell Rep. 2016 May 17; 15(7): 1455–1466. Published online 2016 May 6. doi: 10.1016/j.celrep.2016.04.045
PMCID:
PMC5325702
AbstractArticlePDF–2.1M
18.
Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression
Li-Hao Huang, Elaina M. Melton, Haibo Li, Paul Sohn, Maximillian A. Rogers, Mary Jo Mulligan-Kehoe, Steven N. Fiering, William F. Hickey, Catherine C. Y. Chang, Ta-Yuan Chang
J Biol Chem. 2016 Mar 18; 291(12): 6232–6244. Published online 2016 Jan 21. doi: 10.1074/jbc.M116.713818
PMCID:
PMC4813549
AbstractArticlePDF–2.9M
19.
Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo
Robert O'Brien, Francesco DeGiacomo, Jennifer Holcomb, Akilah Bonner, Karen L. Ring, Ningzhe Zhang, Khan Zafar, Andreas Weiss, Brenda Lager, Birgit Schilling, Bradford W. Gibson, Sylvia Chen, Seung Kwak, Lisa M. Ellerby
J Biol Chem. 2015 Jul 31; 290(31): 19287–19306. Published online 2015 May 29. doi: 10.1074/jbc.M114.623561
PMCID:
PMC4521048
AbstractArticlePDF–3.5M
20.
A compendium of expression patterns of cholesterol biosynthetic enzymes in the mouse embryo
Melda Şişecioğlu, Harun Budak, Lars Geffers, Murat Çankaya, Mehmet Çiftci, Christina Thaller, Gregor Eichele, Ömer İrfan Küfrevioğlu, Hasan Özdemir
J Lipid Res. 2015 Aug; 56(8): 1551–1559. doi: 10.1194/jlr.M059634
PMCID:
PMC4513996
AbstractArticlePDF–3.4M

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