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Select item 113852401.

Weighted gene co-expression network analysis identified GBP2 connected to PPARα activity and liver cancer

Mandana AmeliMojarad, Melika AmeliMojarad, Xiaonan Cui

Sci Rep. 2024; 14: 20745. Published online 2024 Sep 5. doi: 10.1038/s41598-024-70832-6

PMCID:: PMC11385240

Abstract Article PDF–1.5M

Select item 112411212.

Current View on PPAR-α and Its Relation to Neurosteroids in Alzheimer’s Disease and Other Neuropsychiatric Disorders: Promising Targets in a Therapeutic Strategy

Sylwia Żulińska, Anna K. Strosznajder, Joanna B. Strosznajder

Int J Mol Sci. 2024 Jul; 25(13): 7106. Published online 2024 Jun 28. doi: 10.3390/ijms25137106

PMCID:: PMC11241121

Abstract Article PDF–2.2M

Select item 111388833.

Peroxisome proliferator-activated receptor α target genes

S. Mandard, M. Müller, S. Kersten

Cell Mol Life Sci. 2004 Feb; 61(4): 393–416. doi: 10.1007/s00018-003-3216-3

PMCID:: PMC11138883

Abstract Article PDF–351K

Select item 107633074.

Pan PPAR agonist stimulation of induced MSCs produces extracellular vesicles with enhanced renoprotective effect for acute kidney injury

Hongduk Kim, Seul Ki Lee, Sungok Hong, Tae Sub Park, Jimin Kim, Soo Kim, Tae Min Kim

Stem Cell Res Ther. 2024; 15: 9. Published online 2024 Jan 2. doi: 10.1186/s13287-023-03577-0

PMCID:: PMC10763307

Abstract Article PDF–2.8M

Select item 107179775.

The association of ACE, ACTN3 and PPARA gene variants with strength phenotypes in middle school-age children

Ildus I. Ahmetov, Dmitry N. Gavrilov, Irina V. Astratenkova, Anastasiya M. Druzhevskaya, Alexandr V. Malinin, Elena E. Romanova, Victor A. Rogozkin

J Physiol Sci. 2013 Jan; 63(1): 79–85. Published online 2012 Sep 16. doi: 10.1007/s12576-012-0233-8

PMCID:: PMC10717977

Abstract Article PDF–207K

Select item 106811236.

Hepatic fibrosis: Targeting peroxisome proliferator-activated receptor alpha from mechanism to medicines

Lijun Gong, Fang Wei, Frank J. Gonzalez, Guolin Li

Hepatology. Author manuscript; available in PMC 2023 Nov 27.

Published in final edited form as: Hepatology. 2023 Nov 1; 78(5): 1625–1653. Published online 2023 Jan 3. doi: 10.1097/HEP.0000000000000182

PMCID:: PMC10681123

Abstract Article PDF–1.3M

Select item 103390647.

Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity

Kenji Saito, Motohiro Sekiya, Kenta Kainoh, Ryunosuke Yoshino, Akio Hayashi, Song-Iee Han, Masaya Araki, Hiroshi Ohno, Yoshinori Takeuchi, Tomomi Tsuyuzaki, Daichi Yamazaki, Chen Wanpei, Lisa Hada, Sho Watanabe, Putu Indah Paramita Adi Putri, Yuki Murayama, Yoko Sugano, Yoshinori Osaki, Hitoshi Iwasaki, Naoya Yahagi, Hiroaki Suzuki, Takafumi Miyamoto, Takashi Matsuzaka, Hitoshi Shimano

J Biol Chem. 2023 Jul; 299(7): 104890. Published online 2023 Jun 5. doi: 10.1016/j.jbc.2023.104890

PMCID:: PMC10339064

Abstract Article PDF–2.0M

Select item 103106708.

miR-4433a-3p promotes granulosa cell apoptosis by targeting peroxisome proliferator–activated receptor alpha and inducing immune cell infiltration in polycystic ovarian syndrome

Lin Zhu, Xi Yao, Ying Mo, Ming-wei Chen, Si-chen Li, Jian-qiao Liu, Hai-ying Liu

J Assist Reprod Genet. 2023 Jun; 40(6): 1447–1459. Published online 2023 May 19. doi: 10.1007/s10815-023-02815-x

PMCID:: PMC10310670

Abstract Article PDF–4.0M

Select item 99700209.

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez

Hepatology. 2023 Jan; 77(1): 239–255. Published online 2022 May 15. doi: 10.1002/hep.32538

PMCID:: PMC9970020

Abstract Article PDF–1.8M

Select item 984914110.

A proteome-scale map of the SARS-CoV-2–human contactome

Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun

Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z

PMCID:: PMC9849141

Abstract Article PDF–7.1M

Select item 980099411.

PPARα: An emerging target of metabolic syndrome, neurodegenerative and cardiovascular diseases

Yijun Lin, Yan Wang, Pei-feng Li

Front Endocrinol (Lausanne) 2022; 13: 1074911. Published online 2022 Dec 16. doi: 10.3389/fendo.2022.1074911

PMCID:: PMC9800994

Abstract Article PDF–1.2M

Select item 977711212.

Exploring the Regulatory Role of ncRNA in NAFLD: A Particular Focus on PPARs

Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Ramkumar Katturajan, Sandra Kannampuzha, Reshma Murali, Arunraj Namachivayam, Raja Ganesan, Kaviyarasi Renu, Abhijit Dey, Balachandar Vellingiri, Sabina Evan Prince

Cells. 2022 Dec; 11(24): 3959. Published online 2022 Dec 7. doi: 10.3390/cells11243959

PMCID:: PMC9777112

Abstract Article PDF–2.5M

Select item 949672013.

Suppression of Hepatic PPARα in Primary Biliary Cholangitis Is Modulated by miR-155

Monika Adamowicz, Agnieszka Kempinska-Podhorodecka, Joanna Abramczyk, Jesus M. Banales, Piotr Milkiewicz, Malgorzata Milkiewicz

Cells. 2022 Sep; 11(18): 2880. Published online 2022 Sep 15. doi: 10.3390/cells11182880

PMCID:: PMC9496720

Abstract Article PDF–2.7M

Select item 945430314.

Reduced peroxisome proliferator-activated receptor-α and bile acid nuclear receptor NR1H4/FXR may affect the hepatic immune microenvironment of biliary atresia

Yingxuan Ma, Li Lu, Kezhe Tan, Zhi Li, Ting Guo, Yibo Wu, Wei Wu, Lulu Zheng, Feilong Fan, Jiayu Mo, Zhenhua Gong

Front Immunol. 2022; 13: 875593. Published online 2022 Aug 25. doi: 10.3389/fimmu.2022.875593

PMCID:: PMC9454303

Abstract Article PDF–14M

Select item 928982015.

PARP1-mediated PPARα poly(ADP-ribosyl)ation suppresses fatty acid oxidation in non-alcoholic fatty liver disease

Kun Huang, Meng Du, Xin Tan, Ling Yang, Xiangrao Li, Yuhan Jiang, Cheng Wang, Fengxiao Zhang, Feng Zhu, Min Cheng, Qinglin Yang, Liqing Yu, Lin Wang, Dan Huang, Kai Huang

J Hepatol. Author manuscript; available in PMC 2022 Jul 18.

Published in final edited form as: J Hepatol. 2017 May; 66(5): 962–977. Published online 2016 Dec 12. doi: 10.1016/j.jhep.2016.11.020

PMCID:: PMC9289820

Abstract Article PDF–3.3M

Select item 926261416.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 891828317.

Fat mass and obesity–associated protein promotes liver steatosis by targeting PPARα

Xiaohui Wei, Jielei Zhang, Min Tang, Xuejiao Wang, Nengguang Fan, Yongde Peng

Lipids Health Dis. 2022; 21: 29. Published online 2022 Mar 13. doi: 10.1186/s12944-022-01640-y

PMCID:: PMC8918283

Abstract Article PDF–2.5M

Select item 870037718.

PXR Suppresses PPARα-Dependent HMGCS2 Gene Transcription by Inhibiting the Interaction between PPARα and PGC1α

Ryota Shizu, Kanako Ezaki, Takumi Sato, Ayaka Sugawara, Takuomi Hosaka, Takamitsu Sasaki, Kouichi Yoshinari

Cells. 2021 Dec; 10(12): 3550. Published online 2021 Dec 16. doi: 10.3390/cells10123550

PMCID:: PMC8700377

Abstract Article PDF–2.5M

Select item 863973119.

Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα

Ozren Stojanović, Jordi Altirriba, Dorothée Rigo, Martina Spiljar, Emilien Evrard, Benedek Roska, Salvatore Fabbiano, Nicola Zamboni, Pierre Maechler, Françoise Rohner-Jeanrenaud, Mirko Trajkovski

Nat Commun. 2021; 12: 7031. Published online 2021 Dec 2. doi: 10.1038/s41467-021-27133-7

PMCID:: PMC8639731

Abstract Article PDF–2.6M

Select item 850875220.

The PPARα and PPARγ Epigenetic Landscape in Cancer and Immune and Metabolic Disorders

Jesús Porcuna, Jorge Mínguez-Martínez, Mercedes Ricote

Int J Mol Sci. 2021 Oct; 22(19): 10573. Published online 2021 Sep 30. doi: 10.3390/ijms221910573

PMCID:: PMC8508752

Abstract Article PDF–1.0M

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