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Items: 1 to 20 of 32

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop
Xiaomin Li, Jianjun Wang, Weihao Lin, Qinzi Yuan, Yanxia Lu, Haowei Wang, Yujia Chen, Lixia Chen, Peiling Dai, Huaicheng Long, Xuenong Li
Mol Cancer. 2022; 21: 135. Published online 2022 Jun 23. doi: 10.1186/s12943-022-01600-1
PMCID:
PMC9219196
AbstractArticlePDF–13M
3.
Elevated Ras related GTP binding B (RRAGB) expression predicts poor overall survival and constructs a prognostic nomogram for colon adenocarcinoma
Jianjia Xiao, Qingqing Liu, Weijie Wu, Ying Yuan, Jie Zhou, Jieyu Shi, Shaorong Zhou
Bioengineered. 2021; 12(1): 4620–4632. Published online 2021 Jul 29. doi: 10.1080/21655979.2021.1956402
PMCID:
PMC8806650
AbstractArticlePDF–5.3M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis
Wei Wang, Zhijie Xia, Jean-Claude Farré, Suresh Subramani
Autophagy. 2018; 14(9): 1574–1585. Published online 2018 Aug 21. doi: 10.1080/15548627.2018.1463120
PMCID:
PMC6135569
AbstractArticlePDF–2.3M
6.
TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer
Jonathan M. Cooper, Yi-Hung Ou, Elizabeth A. McMillan, Rachel M. Vaden, Aubhishek Zaman, Brian O. Bodemann, Gurbani Makkar, Bruce A. Posner, Michael A. White
Cancer Res. Author manuscript; available in PMC 2018 Sep 15.
Published in final edited form as: Cancer Res. 2017 Sep 15; 77(18): 5077–5094. Published online 2017 Jul 17. doi: 10.1158/0008-5472.CAN-17-0829
PMCID:
PMC5833933
AbstractArticlePDF–2.9M
7.
Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1)
Shusaku Shibutani, Hana Okazaki, Hiroyuki Iwata
J Biol Chem. 2017 Nov 3; 292(44): 18052–18061. Published online 2017 Aug 14. doi: 10.1074/jbc.M117.776443
PMCID:
PMC5672031
AbstractArticlePDF–2.2M
8.
SZT2 Dictates GATOR Control of mTORC1 Signaling
Min Peng, Na Yin, Ming O. Li
Nature. Author manuscript; available in PMC 2017 Aug 24.
Published in final edited form as: Nature. 2017 Mar 16; 543(7645): 433–437. Published online 2017 Feb 15. doi: 10.1038/nature21378
Correction in:
Nature. 2018 May 16
PMCID:
PMC5570594
AbstractArticlePDF–2.1M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
TRIMs and Galectins globally cooperate and TRIM16 and Galectin-3 co-direct autophagy in endomembrane damage homeostasis
Santosh Chauhan, Suresh Kumar, Ashish Jain, Marisa Ponpuak, Michal H. Mudd, Tomonori Kimura, Seong Won Choi, Ryan Peters, Michael Mandell, Jack-Ansgar Bruun, Terje Johansen, Vojo Deretic
Dev Cell. Author manuscript; available in PMC 2017 Oct 10.
Published in final edited form as: Dev Cell. 2016 Oct 10; 39(1): 13–27. Published online 2016 Sep 29. doi: 10.1016/j.devcel.2016.08.003
PMCID:
PMC5104201
AbstractArticlePDF–2.0M
11.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
12.
SLC38A9 is a component of the lysosomal amino acid-sensing machinery that controls mTORC1
Manuele Rebsamen, Lorena Pochini, Taras Stasyk, Mariana E. G. de Araújo, Michele Galluccio, Richard K. Kandasamy, Berend Snijder, Astrid Fauster, Elena L. Rudashevskaya, Manuela Bruckner, Stefania Scorzoni, Przemyslaw A. Filipek, Kilian V. M. Huber, Johannes Bigenzahn, Leonhard X. Heinz, Claudine Kraft, Keiryn L. Bennett, Cesare Indiveri, Lukas A. Huber, Giulio Superti-Furga
Nature. Author manuscript; available in PMC 2015 Sep 26.
Published in final edited form as: Nature. 2015 Mar 26; 519(7544): 477–481. Published online 2015 Jan 7. doi: 10.1038/nature14107
PMCID:
PMC4376665
AbstractArticlePDF–2.4M
13.
Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2
Constantinos Demetriades, Nikolaos Doumpas, Aurelio A. Teleman
Cell. Author manuscript; available in PMC 2015 Mar 2.
Published in final edited form as: Cell. 2014 Feb 13; 156(4): 786–799. doi: 10.1016/j.cell.2014.01.024
PMCID:
PMC4346203
AbstractArticlePDF–2.7M
14.
The amino acid transporter SLC38A9 is a key component of a lysosomal membrane complex that signals arginine sufficiency to mTORC1
Shuyu Wang, Zhi-Yang Tsun, Rachel Wolfson, Kuang Shen, Gregory A. Wyant, Molly E. Plovanich, Elizabeth D. Yuan, Tony D. Jones, Lynne Chantranupong, William Comb, Tim Wang, Liron Bar-Peled, Roberto Zoncu, Christoph Straub, Choah Kim, Jiwon Park, Bernardo L. Sabatini, David M. Sabatini
Science. Author manuscript; available in PMC 2015 Jan 15.
Published in final edited form as: Science. 2015 Jan 9; 347(6218): 188–194. Published online 2015 Jan 7. doi: 10.1126/science.1257132
PMCID:
PMC4295826
AbstractArticlePDF–1.6M
15.
Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling
Min Peng, Na Yin, Ming O. Li
Cell. Author manuscript; available in PMC 2015 Sep 25.
Published in final edited form as: Cell. 2014 Sep 25; 159(1): 122–133. doi: 10.1016/j.cell.2014.08.038
PMCID:
PMC4181352
AbstractArticlePDF–2.7M
16.
Genome-wide association study of smoking behaviors among Bangladeshi adults
Maria Argos, Lin Tong, Brandon L. Pierce, Muhammad Rakibuz-Zaman, Alauddin Ahmed, Tariqul Islam, Mahfuzar Rahman, Rachelle Paul-Brutus, Ronald Rahaman, Shantanu Roy, Farzana Jasmine, Muhammad G. Kibriya, Habibul Ahsan
J Med Genet. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: J Med Genet. 2014 May; 51(5): 327–333. Published online 2014 Mar 24. doi: 10.1136/jmedgenet-2013-102151
PMCID:
PMC4126189
AbstractArticlePDF–672K
17.
A high-throughput approach for measuring temporal changes in the interactome
Anders R. Kristensen, Joerg Gsponer, Leonard J. Foster
Nat Methods. Author manuscript; available in PMC 2014 Mar 14.
Published in final edited form as: Nat Methods. 2012 Sep; 9(9): 907–909. Published online 2012 Aug 5. doi: 10.1038/nmeth.2131
PMCID:
PMC3954081
AbstractArticlePDF–632K
18.
mTor Regulates Lysosomal ATP-sensitive Two-Pore Na+ Channel to Adapt to Metabolic State
Chunlei Cang, Yandong Zhou, Betsy Navarro, Young-jun Seo, Kimberly Aranda, Lucy Shi, Shyuefang Battaglia-Hsu, Itzhak Nissim, David E. Clapham, Dejian Ren
Cell. Author manuscript; available in PMC 2014 Feb 14.
Published in final edited form as: Cell. 2013 Feb 14; 152(4): 778–790. Published online 2013 Feb 7. doi: 10.1016/j.cell.2013.01.023
PMCID:
PMC3908667
AbstractArticlePDF–3.6M
19.
Amino Acids Activate Mammalian Target of Rapamycin (mTOR) Complex 1 without Changing Rag GTPase Guanyl Nucleotide Charging
Noriko Oshiro, Joseph Rapley, Joseph Avruch
J Biol Chem. 2014 Jan 31; 289(5): 2658–2674. Published online 2013 Dec 11. doi: 10.1074/jbc.M113.528505
PMCID:
PMC3908400
AbstractArticlePDF–2.6M
20.
Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases
Constance S. Petit, Agnes Roczniak-Ferguson, Shawn M. Ferguson
J Cell Biol. 2013 Sep 30; 202(7): 1107–1122. doi: 10.1083/jcb.201307084
PMCID:
PMC3787382
AbstractArticlePDF–4.1M

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