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Items: 1 to 20 of 30

1.
Gene structure and function of the 2′-5′-oligoadenylate synthetase family
J. Justesen, R. Hartmann, N.O. Kjeldgaard
Cell Mol Life Sci. 2000 Oct; 57(11): 1593–1612. doi: 10.1007/PL00000644
PMCID:
PMC11146851
AbstractArticlePDF–1.2M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Long noncoding RNA SATB1-AS1 contributes to the chemotherapy resistance through the microRNA-580/ 2’-5’-oligoadenylate synthetase 2 axis in acute myeloid leukemia
Hong Zhou, Xiaofeng Jia, Fan Yang, Pengfei Shi
Bioengineered. 2021; 12(1): 6403–6417. Published online 2021 Sep 13. doi: 10.1080/21655979.2021.1971508
PMCID:
PMC8806783
AbstractArticlePDF–5.2M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19
Hibah Shaath, Radhakrishnan Vishnubalaji, Eyad Elkord, Nehad M. Alajez
Cells. 2020 Nov; 9(11): 2374. Published online 2020 Oct 29. doi: 10.3390/cells9112374
PMCID:
PMC7693119
AbstractArticlePDF–6.0M
6.
Quantitative Proteomic Profile of Psoriatic Epidermis Identifies OAS2 as a Novel Biomarker for Disease Activity
Yuan Zhou, Ping Wang, Bing-Xi Yan, Xue-Yan Chen, Lilla Landeck, Zhao-Yuan Wang, Xin-Xin Li, Jing Zhang, Min Zheng, Xiao-Yong Man
Front Immunol. 2020; 11: 1432. Published online 2020 Jul 31. doi: 10.3389/fimmu.2020.01432
PMCID:
PMC7410923
AbstractArticlePDF–2.5M
7.
Structural and Hydrodynamic Characterization of Dimeric Human Oligoadenylate Synthetase 2
Amit Koul, Darren Gemmill, Nikhat Lubna, Markus Meier, Natalie Krahn, Evan P. Booy, Jörg Stetefeld, Trushar R. Patel, Sean A. McKenna
Biophys J. 2020 Jun 2; 118(11): 2726–2740. Published online 2020 May 1. doi: 10.1016/j.bpj.2020.04.025
PMCID:
PMC7264852
AbstractArticlePDF–2.5M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection
Jeffery T. Kwock, Chelsea Handfield, Jutamas Suwanpradid, Peter Hoang, Michael J. McFadden, Kevin F. Labagnara, Lauren Floyd, Jessica Shannon, Ranjitha Uppala, Mrinal K. Sarkar, Johann E. Gudjonsson, David L. Corcoran, Helen M. Lazear, Gregory Sempowski, Stacy M. Horner, Amanda S. MacLeod
Sci Adv. 2020 Apr; 6(14): eaay3245. Published online 2020 Apr 1. doi: 10.1126/sciadv.aay3245
PMCID:
PMC7112749
AbstractArticlePDF–621K
10.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
11.
Interactome and proteome dynamics uncover immune modulatory associations of the pathogen sensing factor cGAS
Krystal K. Lum, Bokai Song, Joel D. Federspiel, Benjamin A. Diner, Timothy Howard, Ileana M. Cristea
Cell Syst. Author manuscript; available in PMC 2019 Dec 26.
Published in final edited form as: Cell Syst. 2018 Dec 26; 7(6): 627–642.e6. Published online 2018 Nov 21. doi: 10.1016/j.cels.2018.10.010
PMCID:
PMC6310102
AbstractArticlePDF–3.5M
12.
The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
Fabian Christoph Franke, Johannes Müller, Miguel Abal, Eduardo Domínguez Medina, Ulrich Nitsche, Henri Weidmann, Solenne Chardonnet, Ewa Ninio, Klaus-Peter Janssen
Cell Mol Gastroenterol Hepatol. 2019; 7(1): 33–53. Published online 2018 Sep 11. doi: 10.1016/j.jcmgh.2018.08.007
PMCID:
PMC6251370
AbstractArticlePDF–5.6M
13.
Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively
Jin Cheon Kim, Ye Jin Ha, Ka Hee Tak, Seon Ae Roh, Yi Hong Kwon, Chan Wook Kim, Yong Sik Yoon, Jong Lyul Lee, Yangsoon Park, Seon-Kyu Kim, Seon-Young Kim, Dong-Hyung Cho, Yong Sung Kim
PLoS One. 2018; 13(8): e0202856. Published online 2018 Aug 27. doi: 10.1371/journal.pone.0202856
PMCID:
PMC6110496
AbstractArticlePDF–5.7M
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
Mx1, OAS1 and OAS2 polymorphisms are associated with the severity of liver disease in HIV/HCV-coinfected patients: A cross-sectional study
Mónica García-Álvarez, Juan Berenguer, María A. Jiménez-Sousa, Daniel Pineda-Tenor, Teresa Aldámiz-Echevarria, Francisco Tejerina, Cristina Diez, Sonia Vázquez-Morón, Salvador Resino
Sci Rep. 2017; 7: 41516. Published online 2017 Jan 31. doi: 10.1038/srep41516
PMCID:
PMC5282518
AbstractArticlePDF–1.4M
16.
Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans
Aaron J. Sams, Anne Dumaine, Yohann Nédélec, Vania Yotova, Carolina Alfieri, Jerome E. Tanner, Philipp W. Messer, Luis B. Barreiro
Genome Biol. 2016; 17: 246. Published online 2016 Nov 29. doi: 10.1186/s13059-016-1098-6
PMCID:
PMC5129249
AbstractArticlePDF–1.3M
17.
Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites
Xiaolian Gu, Linda Boldrup, Philip J. Coates, Robin Fahraeus, Elisabet Nylander, Christos Loizou, Katarina Olofsson, Lena Norberg-Spaak, Ola Gärskog, Karin Nylander
Sci Rep. 2016; 6: 32579. Published online 2016 Aug 30. doi: 10.1038/srep32579
PMCID:
PMC5004144
AbstractArticlePDF–693K
18.
Extracellular 2′5′‐oligoadenylate synthetase 2 mediates T‐cell receptor CD3‐ζ chain down‐regulation via caspase‐3 activation in oral cancer
Asif A. Dar, Trupti N. Pradhan, Dakshayni P. Kulkarni, Sagar U. Shah, Kanury V. Rao, Devendra A. Chaukar, Anil K. D'Cruz, Shubhada V. Chiplunkar
Immunology. 2016 Feb; 147(2): 251–264. Published online 2015 Dec 27. doi: 10.1111/imm.12560
PMCID:
PMC4717238
AbstractArticlePDF–880K
19.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
20.
HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells
Sami Kukkonen, Maria Del Pilar Martinez-Viedma, Nayoung Kim, Mariana Manrique, Anna Aldovini
Retrovirology. 2014; 11: 30. Published online 2014 Apr 17. doi: 10.1186/1742-4690-11-30
PMCID:
PMC4036831
AbstractArticlePDF–1.8M

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