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Select item 112971571.

Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development

Hao Zeng, Xue Yang, Kai Liao, Xin Zuo, Lihong Liang, Dalian He, Rong Ju, Bowen Wang, Jin Yuan

Exp Mol Med. 2024 Jul; 56(7): 1655–1666. Published online 2024 Jul 2. doi: 10.1038/s12276-024-01269-0

PMCID:: PMC11297157

Abstract Article PDF–3.3M

Select item 105096262.

MUC4基因突变在经典型阵发性睡眠性血红蛋白尿症患者血栓事件中的作用及临床意义

陈颖莹, 刘惠, 李丽燕, 李丽娟, 王化泉, 宋嘉, 吴玉红, 关晶, 邢莉民, 王国锦, 瞿文, 刘鸿, 王晓明, 邵宗鸿, 付蓉

Zhonghua Xue Ye Xue Za Zhi. 2023 Jul; 44(7): 561–566. Chinese. doi: 10.3760/cma.j.issn.0253-2727.2023.07.007

PMCID:: PMC10509626

Abstract Article PDF–922K

Select item 103100263.

Genetic variants of MUC4 are associated with susceptibility to and mortality of colorectal cancer and exhibit synergistic effects with LDL-C levels

Min Jung Kwon, Jeong Yong Lee, Eo Jin Kim, Eun Ju Ko, Chang Soo Ryu, Hye Jung Cho, Hak Hoon Jun, Jong Woo Kim, Nam Keun Kim

PLoS One. 2023; 18(6): e0287768. Published online 2023 Jun 29. doi: 10.1371/journal.pone.0287768

PMCID:: PMC10310026

Abstract Article PDF–1.0M

Select item 102660714.

Mucin 4 Confers Gemcitabine Resistance and an Unfavorable Prognosis in Patients with Cholangiocarcinoma via AKT Activation

Yi-Ru Pan, Chiao-En Wu, Shih-Ming Jung, Shih-Chiang Huang, Sheng-Hsuan Lin, Wen-Chi Chou, Yu-Chan Chang, Ming-Huang Chen, Tsai-Hsien Hung, Alice L. Yu, Wen-Kuan Huang, Chun-Nan Yeh

Int J Biol Sci. 2023; 19(9): 2772–2786. Published online 2023 May 21. doi: 10.7150/ijbs.79126

PMCID:: PMC10266071

Abstract Article PDF–7.1M

Select item 99224685.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 92227986.

Association Study between Mucin 4 (MUC4) Polymorphisms and Idiopathic Recurrent Pregnancy Loss in a Korean Population

Ji-Hyang Kim, Han-Sung Park, Jeong-Yong Lee, Eun-Ju Ko, Young-Ran Kim, Hee-Young Cho, Woo-Sik Lee, Eun-Hee Ahn, Nam-Keun Kim

Genes (Basel) 2022 Jun; 13(6): 937. Published online 2022 May 24. doi: 10.3390/genes13060937

PMCID:: PMC9222798

Abstract Article PDF–430K

Select item 88742297.

A flexible summary statistics-based colocalization method with application to the mucin cystic fibrosis lung disease modifier locus

Fan Wang, Naim Panjwani, Cheng Wang, Lei Sun, Lisa J. Strug

Am J Hum Genet. 2022 Feb 3; 109(2): 253–269. Published online 2022 Jan 21. doi: 10.1016/j.ajhg.2021.12.012

PMCID:: PMC8874229

Abstract Article PDF–1.2M

Select item 86976358.

The role of membrane mucin MUC4 in breast cancer metastasis

Courtney A. Dreyer, Kacey VanderVorst, Savannah Free, Ashley Rowson-Hodel, Kermit L. Carraway, III

Endocr Relat Cancer. Author manuscript; available in PMC 2021 Dec 23.

Published in final edited form as: Endocr Relat Cancer. 2021 Nov 24; 29(1): R17–R32. Published online 2021 Nov 24. doi: 10.1530/ERC-21-0083

PMCID:: PMC8697635

Abstract Article PDF–897K

Select item 80582549.

MUC4 is expressed in alveolar rhabdomyosarcoma

Erna Forgó, Jason L. Hornick, Gregory W. Charville

Histopathology. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Histopathology. 2020 Dec 24 : 10.1111/his.14321. Published online 2020 Dec 24. doi: 10.1111/his.14321

PMCID:: PMC8058254

Abstract Article PDF–734K

Select item 803491610.

Mucin 4 mutation is associated with tumor mutation burden and promotes antitumor immunity in colon cancer patients

Linglong Peng, Yang Li, Haitao Gu, Ling Xiang, Yongfu Xiong, Rong Wang, He Zhou, Jijian Wang

Aging (Albany NY) 2021 Mar 31; 13(6): 9043–9055. Published online 2021 Mar 14. doi: 10.18632/aging.202756

PMCID:: PMC8034916

Abstract Article PDF–1.9M

Select item 798125211.

MUC4 enhances gemcitabine resistance and malignant behaviour in pancreatic cancer cells expressing cancer-associated short O-glycans

Satish Sagar, Pramila D. Leiphrakpam, Divya Thomas, Kyle L. McAndrews, Thomas C. Caffrey, Benjamin J. Swanson, Henrik Clausen, Hans H. Wandall, Michael A. Hollingsworth, Prakash Radhakrishnan

Cancer Lett. Author manuscript; available in PMC 2022 Apr 10.

Published in final edited form as: Cancer Lett. 2021 Apr 10; 503: 91–102. Published online 2021 Jan 22. doi: 10.1016/j.canlet.2021.01.015

PMCID:: PMC7981252

Abstract Article PDF–3.8M

Select item 780232012.

Comprehensive assessments of germline deletion structural variants reveal the association between prognostic MUC4 and CEP72 deletions and immune response gene expression in colorectal cancer patients

Peng-Chan Lin, Hui-O Chen, Chih-Jung Lee, Yu-Min Yeh, Meng-Ru Shen, Jung-Hsien Chiang

Hum Genomics. 2021; 15: 3. Published online 2021 Jan 11. doi: 10.1186/s40246-020-00302-3

PMCID:: PMC7802320

Abstract Article PDF–3.4M

Select item 774454813.

Bile accelerates carcinogenic processes in pancreatic ductal adenocarcinoma cells through the overexpression of MUC4

Eleonóra Gál, Zoltán Veréb, Lajos Kemény, Dávid Rakk, András Szekeres, Eszter Becskeházi, László Tiszlavicz, Tamás Takács, László Czakó, Péter Hegyi, Viktória Venglovecz

Sci Rep. 2020; 10: 22088. Published online 2020 Dec 16. doi: 10.1038/s41598-020-79181-6

PMCID:: PMC7744548

Abstract Article PDF–9.4M

Select item 749985614.

Smoking-associated increase in mucins 1 and 4 in human airways

Heta Merikallio, Riitta Kaarteenaho, Sara Lindén, Médea Padra, Reza Karimi, Chuan-Xing Li, Elisa Lappi-Blanco, Åsa M. Wheelock, Magnus C. Sköld

Respir Res. 2020; 21: 239. Published online 2020 Sep 18. doi: 10.1186/s12931-020-01498-7

PMCID:: PMC7499856

Abstract Article PDF–2.3M

Select item 737742015.

Family-based exome sequencing combined with linkage analyses identifies rare susceptibility variants of MUC4 for gastric cancer

Yoon Jin Choi, Jung Hun Ohn, Nayoung Kim, Wonji Kim, Kyungtaek Park, Sungho Won, Lee Sael, Cheol Min Shin, Sun Min Lee, Sejoon Lee, Hyun Joo An, Dong Man Jang, Byung Woo Han, Hye Seung Lee, Seung Joo Kang, Joo Sung Kim, Dong Ho Lee

PLoS One. 2020; 15(7): e0236197. Published online 2020 Jul 23. doi: 10.1371/journal.pone.0236197

PMCID:: PMC7377420

Abstract Article PDF–2.5M

Select item 701275816.

Recurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-Negative Sclerosing Epithelioid Fibrosarcoma

Yu-Chien Kao, Jen-Chieh Lee, Lei Zhang, Yun-Shao Sung, David Swanson, Tsung-Han Hsieh, Yun-Ru Liu, Narasimhan P Agaram, Hsuan-Ying Huang, Brendan C. Dickson, Cristina R. Antonescu

Am J Surg Pathol. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Am J Surg Pathol. 2020 Mar; 44(3): 368–377. doi: 10.1097/PAS.0000000000001382

PMCID:: PMC7012758

Abstract Article PDF–2.3M

Select item 693077617.

The Antioxidant Alpha-Lipoic Acid Inhibits Proliferation and Invasion of Human Gastric Cancer Cells via Suppression of STAT3-Mediated MUC4 Gene Expression

Yu Yang, Erhu Fang, Jiajun Luo, Hongxue Wu, Yue Jiang, Ying Liu, Shilun Tong, Zhihua Wang, Rui Zhou, Qiang Tong

Oxid Med Cell Longev. 2019; 2019: 3643715. Published online 2019 Dec 13. doi: 10.1155/2019/3643715

PMCID:: PMC6930776

Abstract Article PDF–1.0M

Select item 651990118.

Single nucleotide polymorphisms within MUC4 are associated with colorectal cancer survival

Shun Lu, Calogerina Catalano, Stefanie Huhn, Barbara Pardini, Linda Partu, Veronika Vymetalkova, Ludmila Vodickova, Miroslav Levy, Thomas Buchler, Kari Hemminki, Pavel Vodicka, Asta Försti

PLoS One. 2019; 14(5): e0216666. Published online 2019 May 15. doi: 10.1371/journal.pone.0216666

Correction in:: PLoS One. 2019; 14(6): e0218064.

PMCID:: PMC6519901

Abstract Article PDF–617K

Select item 648360219.

Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation

Xiuxia Zhou, Carol L. Kinlough, Rebecca P. Hughey, Mingzhu Jin, Hideki Inoue, Emily Etling, Brian D. Modena, Naftali Kaminski, Eugene R. Bleecker, Deborah A. Meyers, Nizar N. Jarjour, John B. Trudeau, Fernando Holguin, Anuradha Ray, Sally E. Wenzel

JCI Insight. 2019 Mar 7; 4(5): e122475. Published online 2019 Mar 7. doi: 10.1172/jci.insight.122475

PMCID:: PMC6483602

Abstract Article PDF–2.1M

Select item 646120520.

Genetic and Transcriptomic Basis of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease

Maaike Vancamelbeke, Tim Vanuytsel, Ricard Farré, Sare Verstockt, Marc Ferrante, Gert Van Assche, Paul Rutgeerts, Frans Schuit, Séverine Vermeire, Ingrid Arijs, Isabelle Cleynen

Inflamm Bowel Dis. Author manuscript; available in PMC 2019 Apr 12.

Published in final edited form as: Inflamm Bowel Dis. 2017 Oct; 23(10): 1718–1729. doi: 10.1097/MIB.0000000000001246