PMC Links for GEO Profiles (Select 131525496) - PMC

Select item 98996521.

A Phase I study of DLYE5953A, an anti-LY6E antibody covalently linked to monomethyl auristatin E, in patients with refractory solid tumors

Sara M. Tolaney, Khanh T. Do, Joseph P. Eder, Patricia M. LoRusso, Colin D. Weekes, Sarat Chandarlapaty, Ching-Wei Chang, Shang-Chiung Chen, Denise Nazzal, Eva Schuth, Flavia Brunstein, Montserrat Carrasco-Triguero, Walter C. Darbonne, Jennifer M. Giltnane, William M. Flanagan, S. Renee Commerford, Alexander Ungewickell, Geoffrey I. Shapiro, Shanu Modi

Clin Cancer Res. Author manuscript; available in PMC 2023 Feb 6.

Published in final edited form as: Clin Cancer Res. 2020 Nov 1; 26(21): 5588–5597. Published online 2020 Jul 21. doi: 10.1158/1078-0432.CCR-20-1067

PMCID:: PMC9899652

Abstract Article PDF–988K

Select item 98491412.

A proteome-scale map of the SARS-CoV-2–human contactome

Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun

Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z

PMCID:: PMC9849141

Abstract Article PDF–7.1M

Select item 89330973.

Multidimension Analysis of the Prognostic Value, Immune Regulatory Function, and ceRNA Network of LY6E in Individuals with Colorectal Cancer

Ting Li, Weidong Liu, Chun Wang, Man Wang, Wenjia Hui, Jiajie Lu, Feng Gao

J Immunol Res. 2022; 2022: 5164265. Published online 2022 Mar 11. doi: 10.1155/2022/5164265

PMCID:: PMC8933097

Abstract Article PDF–1.9M

Select item 79169994.

LY6E impairs coronavirus fusion and confers immune control of viral disease

Stephanie Pfaender, Katrina B. Mar, Eleftherios Michailidis, Annika Kratzel, Ian N. Boys, Philip V`kovski, Wenchun Fan, Jenna N. Kelly, Dagny Hirt, Nadine Ebert, Hanspeter Stalder, Hannah Kleine-Weber, Markus Hoffmann, H. Heinrich Hoffmann, Mohsan Saeed, Ronald Dijkman, Eike Steinmann, Mary Wight-Carter, Matthew B. McDougal, Natasha W. Hanners, Stefan Pöhlmann, Tom Gallagher, Daniel Todt, Gert Zimmer, Charles M. Rice, John W. Schoggins, Volker Thiel

Nat Microbiol. Author manuscript; available in PMC 2021 Feb 28.

Published in final edited form as: Nat Microbiol. 2020 Nov; 5(11): 1330–1339. Published online 2020 Jul 23. doi: 10.1038/s41564-020-0769-y

PMCID:: PMC7916999

Abstract Article PDF–5.3M

Select item 74595695.

LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2

Xuesen Zhao, Shuangli Zheng, Danying Chen, Mei Zheng, Xinglin Li, Guoli Li, Hanxin Lin, Jinhong Chang, Hui Zeng, Ju-Tao Guo

J Virol. 2020 Sep; 94(18): e00562-20. Prepublished online 2020 Jul 8. Published online 2020 Aug 31. doi: 10.1128/JVI.00562-20

PMCID:: PMC7459569

Abstract Article PDF–3.4M

Select item 73220676.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 68936468.

Emerging Role of LY6E in Virus–Host Interactions

Jingyou Yu, Shan-Lu Liu

Viruses. 2019 Nov; 11(11): 1020. Published online 2019 Nov 3. doi: 10.3390/v11111020

PMCID:: PMC6893646

Abstract Article PDF–766K

Select item 64305489.

CD4-Dependent Modulation of HIV-1 Entry by LY6E

Jingyou Yu, Chen Liang, Shan-Lu Liu

J Virol. 2019 Apr 1; 93(7): e01866-18. Prepublished online 2019 Jan 23. Published online 2019 Mar 21. doi: 10.1128/JVI.01866-18

PMCID:: PMC6430548

Abstract Article PDF–2.9M

Select item 612719210.

LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step

Katrina B. Mar, Nicholas R. Rinkenberger, Ian N. Boys, Jennifer L. Eitson, Matthew B. McDougal, R. Blake Richardson, John W. Schoggins

Nat Commun. 2018; 9: 3603. Published online 2018 Sep 6. doi: 10.1038/s41467-018-06000-y

PMCID:: PMC6127192

Abstract Article PDF–1.4M

Select item 567858111.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 537778212.

Interferon-inducible LY6E Protein Promotes HIV-1 Infection

Jingyou Yu, Chen Liang, Shan-Lu Liu

J Biol Chem. 2017 Mar 17; 292(11): 4674–4685. Published online 2017 Jan 27. doi: 10.1074/jbc.M116.755819

PMCID:: PMC5377782

Abstract Article PDF–2.3M

Select item 532319613.

LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis

Chan Joo Yeom, Lihua Zeng, Yoko Goto, Akiyo Morinibu, Yuxi Zhu, Kazumi Shinomiya, Minoru Kobayashi, Satoshi Itasaka, Michio Yoshimura, Cheol-Goo Hur, Hideaki Kakeya, Ester M. Hammond, Masahiro Hiraoka, Hiroshi Harada

Oncotarget. 2016 Oct 4; 7(40): 65837–65848. Published online 2016 Aug 29. doi: 10.18632/oncotarget.11670

PMCID:: PMC5323196

Abstract Article PDF–3.9M

Select item 491062314.

Ly6E/K signaling to TGF-β promotes breast cancer progression, immune escape and drug resistance

Midrar Al Hossiny, Linlin Luo, William R Frazier, Noriko Steiner, Yuriy Gusev, Bhaskar Kallakury, Eric Glasgow, Karen Creswell, Subha Madhavan, Rakesh Kumar, Geeta Upadhyay

Cancer Res. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Cancer Res. 2016 Jun 1; 76(11): 3376–3386. Published online 2016 Apr 11. doi: 10.1158/0008-5472.CAN-15-2654

PMCID:: PMC4910623

Abstract Article PDF–3.0M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 178328716.

Inhibition of the function of the FcγRIIB by a monoclonal antibody to thymic shared antigen-1, a Ly-6 family antigen

Linna Ding, Ethan M Shevach

Immunology. 2001 Sep; 104(1): 28–36. doi: 10.1046/j.0019-2805.2001.01275.x

PMCID:: PMC1783287

Abstract Article PDF–281K

Select item 52892817.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 13924118.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

Select item 13355719.

Essential Role for the Lymphostromal Plasma Membrane Ly-6 Superfamily Molecule Thymic Shared Antigen 1 in Development of the Embryonic Adrenal Gland

David J. Zammit, Stuart P. Berzins, Jason W. Gill, Elise S. Randle-Barrett, Louise Barnett, Frank Koentgen, Gavin W. Lambert, Richard P. Harvey, Richard L. Boyd, Brendan J. Classon

Mol Cell Biol. 2002 Feb; 22(3): 946–952. doi: 10.1128/MCB.22.3.946-952.2002

PMCID:: PMC133557

Abstract Article PDF–465K

Select item 3916120.

RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.

M Mao, M Yu, J H Tong, J Ye, J Zhu, Q H Huang, G Fu, L Yu, S Y Zhao, S Waxman, M Lanotte, Z Y Wang, J Z Tan, S J Chan, Z Chen

Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12): 5910–5914. doi: 10.1073/pnas.93.12.5910

PMCID:: PMC39161

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