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Select item 113196511.

Distinct conformational states enable transglutaminase 2 to promote cancer cell survival versus cell death

Cody Aplin, Kara A. Zielinski, Suzette Pabit, Deborah Ogunribido, William P. Katt, Lois Pollack, Richard A. Cerione, Shawn K. Milano

Commun Biol. 2024; 7: 982. Published online 2024 Aug 13. doi: 10.1038/s42003-024-06672-x

PMCID:: PMC11319651

Abstract Article PDF–6.9M

Select item 112379302.

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein

Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo

J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390

PMCID:: PMC11237930

Abstract Article PDF–3.8M

Select item 111155023.

Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA

Essi Myrsky, Sergio Caja, Zsofi Simon-Vecsei, Ilma R. Korponay-Szabo, Cristina Nadalutti, Russell Collighan, Alexandre Mongeot, Martin Griffin, Markku Mäki, Katri Kaukinen, Katri Lindfors

Cell Mol Life Sci. 2009 Oct; 66(20): 3375–3385. Published online 2009 Aug 13. doi: 10.1007/s00018-009-0116-1

PMCID:: PMC11115502

Abstract Article PDF–473K

Select item 110487924.

Biological Implications and Functional Significance of Transglutaminase Type 2 in Nervous System Tumors

Mariachiara Buccarelli, Giorgia Castellani, Vincenzo Fiorentino, Cristina Pizzimenti, Simone Beninati, Lucia Ricci-Vitiani, Maria Luisa Scattoni, Carlo Mischiati, Francesco Facchiano, Claudio Tabolacci

Cells. 2024 Apr; 13(8): 667. Published online 2024 Apr 11. doi: 10.3390/cells13080667

PMCID:: PMC11048792

Abstract Article PDF–1.6M

Select item 109317035.

The Role of Transglutaminase 2 in Cancer: An Update

Elisabetta Zaltron, Federica Vianello, Alessia Ruzza, Alberta Palazzo, Valentina Brillo, Ilaria Celotti, Matteo Scavezzon, Federica Rossin, Luigi Leanza, Filippo Severin

Int J Mol Sci. 2024 Mar; 25(5): 2797. Published online 2024 Feb 28. doi: 10.3390/ijms25052797

PMCID:: PMC10931703

Abstract Article PDF–4.5M

Select item 108690546.

Prognostic significance of RKIP, TGM2, and CMTM4 expression in oral squamous cell carcinoma

Tianyu Luo, Tao Xu, Yurong Ou, Hongfei Ci, Junhui Sun

Medicine (Baltimore) 2024 Feb 16; 103(7): e37278. Published online 2024 Feb 16. doi: 10.1097/MD.0000000000037278

PMCID:: PMC10869054

Abstract Article PDF–815K

Select item 107999037.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 105818968.

Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therapeutic target

Patrizia Malkomes, Ilaria Lunger, Elsie Oppermann, Johannes Lorenz, Sara Fatima Faqar-Uz-Zaman, Jiaoyan Han, Sabrina Bothur, Paul Ziegler, Katrin Bankov, Peter Wild, Wolf Otto Bechstein, Michael A. Rieger

Cancer Gene Ther. 2023; 30(10): 1346–1354. Published online 2023 Jul 13. doi: 10.1038/s41417-023-00641-y

PMCID:: PMC10581896

Abstract Article PDF–2.5M

Select item 105658769.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1047785410.

Separate Gut Plasma Cell Populations Produce Auto‐Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis

Saykat Das, Jorunn Stamnaes, Esko Kemppainen, Kaisa Hervonen, Knut E. A. Lundin, Naveen Parmar, Frode L. Jahnsen, Jørgen Jahnsen, Katri Lindfors, Teea Salmi, Rasmus Iversen, Ludvig M. Sollid

Adv Sci (Weinh) 2023 Sep; 10(25): 2300401. Published online 2023 Jul 9. doi: 10.1002/advs.202300401

Correction in:: Adv Sci (Weinh). 2024 Jun; 11(21): 2400894.

PMCID:: PMC10477854

Abstract Article PDF–1.5M

Select item 1046271111.

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

Augusto C. Montezano, Livia L. Camargo, Sheon Mary, Karla B Neves, Francisco J Rios, Ross Stein, Rheure A. Lopes, Wendy Beattie, Jacqueline Thomson, Vanessa Herder, Agnieszka M. Szemiel, Steven McFarlane, Massimo Palmarini, Rhian M. Touyz

Sci Rep. 2023; 13: 14086. Published online 2023 Aug 28. doi: 10.1038/s41598-023-41115-3

PMCID:: PMC10462711

Abstract Article PDF–1.3M

Select item 1029875112.

Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease

Sunniva F. Amundsen, Jorunn Stamnaes, Knut E. A. Lundin, Ludvig M. Sollid

PLoS One. 2023; 18(6): e0287662. Published online 2023 Jun 27. doi: 10.1371/journal.pone.0287662

PMCID:: PMC10298751

Abstract Article PDF–1.7M

Select item 1023742213.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1017006814.

Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines

Adeola Grace Atobatele, Elisa Tonoli, Jayakumar Vadakekolathu, Maria Pia Savoca, Melissa Barr, Yukti Kataria, Marta Rossanese, Izhar Burhan, Stephanie McArdle, Daniela Caccamo, Elisabetta A. M. Verderio

Cell Death Dis. 2023 May; 14(5): 317. Published online 2023 May 9. doi: 10.1038/s41419-023-05818-9

PMCID:: PMC10170068

Abstract Article PDF–2.7M

Select item 1015223715.

circFNDC3B Accelerates Vasculature Formation and Metastasis in Oral Squamous Cell Carcinoma

Xiang Li, Chenxing Wang, Hang Zhang, Yangjie Li, Deqiang Hou, Dingshan Liu, Rongyao Xu, Jie Cheng, Laikui Liu, Yu Fu, Jinhai Ye, Hongbing Jiang

Cancer Res. 2023 May 2; 83(9): 1459–1475. Published online 2023 Feb 22. doi: 10.1158/0008-5472.CAN-22-2585

PMCID:: PMC10152237

Abstract Article PDF–22M

Select item 1014884316.

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun

Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y

PMCID:: PMC10148843

Abstract Article PDF–11M

Select item 1007499917.

Transglutaminase 2 enhances hepatocyte growth factor signaling to drive the mesothelioma cancer cell phenotype

Warren Naselsky, Gautam Adhikary, Suruchi Shrestha, Xi Chen, Geraldine Ezeka, Wen Xu, Joseph S Friedberg, Richard L. Eckert

Mol Carcinog. Author manuscript; available in PMC 2023 Apr 5.

Published in final edited form as: Mol Carcinog. 2022 Jun; 61(6): 537–548. Published online 2022 Mar 23. doi: 10.1002/mc.23399

PMCID:: PMC10074999

Abstract Article PDF–1.5M

Select item 995044718.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 994162019.

A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells

Itziar González-Moro, Henar Rojas-Márquez, Maialen Sebastian-delaCruz, Jon Mentxaka-Salgado, Ane Olazagoitia-Garmendia, Luis Manuel Mendoza, Aina Lluch, Federica Fantuzzi, Carmen Lambert, Jessica Ares Blanco, Lorella Marselli, Piero Marchetti, Miriam Cnop, Elías Delgado, José Manuel Fernández-Real, Francisco José Ortega, Ainara Castellanos-Rubio, Izortze Santin

Front Endocrinol (Lausanne) 2023; 14: 1101934. Published online 2023 Feb 7. doi: 10.3389/fendo.2023.1101934

PMCID:: PMC9941620

Abstract Article PDF–1013K

Select item 987418320.

Type 2 transglutaminase in the nucleus: the new epigenetic face of a cytoplasmic enzyme

Federica Rossin, Fabiola Ciccosanti, Manuela D’Eletto, Luca Occhigrossi, Gian Maria Fimia, Mauro Piacentini

Cell Mol Life Sci. 2023 Feb; 80(2): 52. Published online 2023 Jan 25. doi: 10.1007/s00018-023-04698-8

PMCID:: PMC9874183

Abstract Article PDF–807K

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