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Select item 111088041.

CERKL-Associated Retinal Dystrophy: Genetics, Phenotype, and Natural History

Malena Daich Varela, Emma S. Duignan, Samantha R. De Silva, Rola Ba-Abbad, Yu Fujinami-Yokokawa, Shaun Leo, Kaoru Fujinami, Omar A. Mahroo, Anthony G. Robson, Andrew R. Webster, Michel Michaelides

Ophthalmol Retina. 2023 Oct; 7(10): 918–931. doi: 10.1016/j.oret.2023.06.007

PMCID:: PMC11108804

Abstract Article PDF–3.0M

Select item 109168662.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 103459633.

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy

Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald

Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535

PMCID:: PMC10345963

Abstract Article PDF–13M

Select item 101307484.

The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand

Yoko K Takada, Scott I Simon, Yoshikazu Takada

Life Sci Alliance. 2023 Jul; 6(7): e202201747. Published online 2023 Apr 25. doi: 10.26508/lsa.202201747

PMCID:: PMC10130748

Abstract Article PDF–3.6M

Select item 99504475.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 98051296.

The integrin ligand SVEP1 regulates GPCR‐mediated vasoconstriction via integrins α9β1 and α4β1

Gavin E. Morris, Matthew J. Denniff, Elisavet Karamanavi, Sarah A. Andrews, Renata B. Kostogrys, Vasiliki Bountziouka, Maryam Ghaderi‐Najafabadi, Noor Shamkhi, George McConnell, Michael A. Kaiser, Laura Carleton, Christine Schofield, Thorsten Kessler, Richard D. Rainbow, Nilesh J. Samani, Thomas R. Webb

Br J Pharmacol. 2022 Nov; 179(21): 4958–4973. Published online 2022 Aug 2. doi: 10.1111/bph.15921

PMCID:: PMC9805129

Abstract Article PDF–28M

Select item 98045207.

Low CD49d expression in newly diagnosed chronic lymphocytic leukaemia may be associated with high‐risk features and reduced treatment‐free‐intervals

Smyth Elizabeth, Kelly Aidan, O' Brien David, Waldron Deirdre, Brophy Sarah, Atkinson Emer, Perera Kanthi, Gerard M. Crotty, Walsh Aileen, Connolly Michelle, Clifford Ruth, O'Leary Hilary, Khan Ashique, Christopher L. Bacon, Smyth Emily, Anthony M. McElligott, Quinn Fiona, Vandenberghe Elisabeth, Waldron Carmel

Eur J Haematol. 2022 Nov; 109(5): 441–446. Published online 2022 Aug 9. doi: 10.1111/ejh.13824

PMCID:: PMC9804520

Abstract Article PDF–830K

Select item 98002288.

慢性淋巴细胞白血病CD49d表达模式与分子遗传学和热点突变基因的相关性

朱静, 刘露, 陈肖, 刘芳, 赵四书, 金慧敏, 仇海荣, 乔纯, 李建勇, 吴雨洁

Zhonghua Xue Ye Xue Za Zhi. 2022 Jun; 43(6): 463–468. Chinese. doi: 10.3760/cma.j.issn.0253-2727.2022.06.004

PMCID:: PMC9800228

Abstract Article PDF–819K

Select item 95701439.

CERKL, a Retinal Dystrophy Gene, Regulates Mitochondrial Transport and Dynamics in Hippocampal Neurons

Rocío García-Arroyo, Gemma Marfany, Serena Mirra

Int J Mol Sci. 2022 Oct; 23(19): 11593. Published online 2022 Sep 30. doi: 10.3390/ijms231911593

PMCID:: PMC9570143

Abstract Article PDF–3.5M

Select item 947545310.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 908313011.

Integrin α4 up-regulation activates the hedgehog pathway to promote arsenic and benzo[α]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis

Jie Xie, Ping Yang, Hsuan-Pei Lin, Yunfei Li, Marco Clementino, William Fenske, Chengfeng Yang, Chunhong Wang, Zhishan Wang

Cancer Lett. Author manuscript; available in PMC 2022 May 9.

Published in final edited form as: Cancer Lett. 2020 Nov 28; 493: 143–155. Published online 2020 Aug 26. doi: 10.1016/j.canlet.2020.08.015

PMCID:: PMC9083130

Abstract Article PDF–2.3M

Select item 859323312.

Enhanced Migratory Capacity of T Lymphocytes in Severe Chagasic Patients Is Correlated With VLA-4 and TNF-α Expression

Luiz Ricardo Berbert, Florencia Belén González, Silvina Raquel Villar, Carlos Vigliano, Susana Lioi, Juan Beloscar, Oscar Adelmo Bottasso, Suse Dayse Silva-Barbosa, Wilson Savino, Ana Rosa Pérez

Front Cell Infect Microbiol. 2021; 11: 713150. Published online 2021 Nov 2. doi: 10.3389/fcimb.2021.713150

PMCID:: PMC8593233

Abstract Article PDF–2.0M

Select item 836418113.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 832771614.

CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity

Julia C. Gutjahr, Elisabeth Bayer, Xiaobing Yu, Julia M. Laufer, Jan P. Höpner, Suzana Tesanovic, Andrea Härzschel, Georg Auer, Tanja Rieß, Astrid Salmhofer, Eva Szenes, Theresa Haslauer, Valerie Durand-Onayli, Andrea Ramspacher, Sandra P. Pennisi, Marc Artinger, Nadja Zaborsky, Alexandre Chigaev, Fritz Aberger, Daniel Neureiter, Lisa Pleyer, Daniel F. Legler, Veronique Orian-Rousseau, Richard Greil, Tanja N. Hartmann

Haematologica. 2021 Aug 1; 106(8): 2102–2113. Published online 2020 Jul 2. doi: 10.3324/haematol.2019.231944

PMCID:: PMC8327716

Abstract Article PDF–1.8M

Select item 826799015.

联合检测粪便中ITGA4和SFRP2基因甲基化在大肠肿瘤诊断和预后中的价值

金红, 庞丽莹, 李华洋, 徐明鑫, 闫海润, 李荣辉

Nan Fang Yi Ke Da Xue Xue Bao. 2021 Jun 20; 41(6): 891–897. Chinese. doi: 10.12122/j.issn.1673-4254.2021.06.12

PMCID:: PMC8267990

Abstract Article PDF–1.2M

Select item 820628616.

Binding of HIV-1 virions to α₄β₇ expressing cells and impact of antagonizing α₄β₇ on HIV-1 infection of primary CD4⁺ T cells

Chang Li, Wei Jin, Tao Du, Biao Wu, Yalan Liu, Robin J. Shattock, Qinxue Hu

Virol Sin. 2014 Dec; 29(6): 381–392. Published online 2014 Dec 10. doi: 10.1007/s12250-014-3525-8

Correction in:: Virol Sin. 2015 Apr; 30(2): 162.

PMCID:: PMC8206286

Abstract Article PDF–2.4M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 804593218.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 776869819.

The V2 loop of HIV gp120 delivers costimulatory signals to CD4⁺ T cells through Integrin α₄β₇ and promotes cellular activation and infection

Livia R. Goes, Alia Sajani, Aida Sivro, Ronke Olowojesiku, Jocelyn C. Ray, Ian Perrone, Jason Yolitz, Alexandre Girard, Louise Leyre, Constantinos Kurt Wibmer, Lynn Morris, Giacomo Gorini, Genoveffa Franchini, Rosemarie D. Mason, Mario Roederer, Saurabh Mehandru, Marcelo A. Soares, Claudia Cicala, Anthony S. Fauci, James Arthos

Proc Natl Acad Sci U S A. 2020 Dec 22; 117(51): 32566–32573. Published online 2020 Dec 7. doi: 10.1073/pnas.2011501117

PMCID:: PMC7768698

Abstract Article PDF–822K

Select item 776396120.

Genetic and Clinical Findings in an Ethnically Diverse Cohort with Retinitis Pigmentosa Associated with Pathogenic Variants in CERKL

Susan M. Downes, Tham Nguyen, Vicky Tai, Suzanne Broadgate, Mital Shah, Saoud Al-Khuzaei, Robert E. MacLaren, Morag Shanks, Penny Clouston, Stephanie Halford

Genes (Basel) 2020 Dec; 11(12): 1497. Published online 2020 Dec 12. doi: 10.3390/genes11121497

PMCID:: PMC7763961

Abstract Article PDF–844K

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