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Select item 100339371.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 95334862.

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop

Yongzhen Mo, Yumin Wang, Yian Wang, Xiangying Deng, Qijia Yan, Chunmei Fan, Shuai Zhang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Qianjin Liao, Can Guo, Yong Li, Guiyuan Li, Zhaoyang Zeng, Weihong Jiang, Wei Xiong, Bo Xiang

Mol Cancer. 2022; 21: 192. Published online 2022 Oct 5. doi: 10.1186/s12943-022-01659-w

PMCID:: PMC9533486

Abstract Article PDF–12M

Select item 92227423.

Phenotypic Expression of Known and Novel Hemoglobin A2-Variants, Hemoglobin A2-Mae Phrik [Delta 52(D3) Asp > Gly, HBD:c.158A > G], Associated with Hemoglobin E [Beta 26(B8) Glu > Lys, HBB:c.79G > A] in Thailand

Amphai Phasit, Sitthichai Panyasai, Monthon Mayoon, Niphawan Jettawan, Surada Satthakarn

Genes (Basel) 2022 Jun; 13(6): 959. Published online 2022 May 27. doi: 10.3390/genes13060959

PMCID:: PMC9222742

Abstract Article PDF–1.4M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 64855076.

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

Iain C. Macaulay, Marloes R. Tijssen, Daphne C. Thijssen-Timmer, Arief Gusnanto, Michael Steward, Philippa Burns, Cordelia F. Langford, Peter D. Ellis, Frank Dudbridge, Jaap-Jan Zwaginga, Nicholas A. Watkins, C. Ellen van der Schoot, Willem H. Ouwehand

Blood. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Blood. 2007 Apr 15; 109(8): 3260–3269. Published online 2006 Dec 27. doi: 10.1182/blood-2006-07-036269

PMCID:: PMC6485507

Abstract Article PDF–4.4M

Select item 62982547.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 53777979.

Heterochromatin Protein 1γ Is a Novel Epigenetic Repressor of Human Embryonic ϵ-Globin Gene Expression

Yadong Wang, Ying Wang, Lingling Ma, Min Nie, Junyi Ju, Ming Liu, Yexuan Deng, Bing Yao, Tao Gui, Xinyu Li, Chan Guo, Chi Ma, Renxiang Tan, Quan Zhao

J Biol Chem. 2017 Mar 24; 292(12): 4811–4817. Published online 2017 Feb 1. doi: 10.1074/jbc.M116.768515

PMCID:: PMC5377797

Abstract Article PDF–1.4M

Select item 500437910.

ε-globin expression is regulated by SUV4-20h1

Yadong Wang, Gerhard Rank, Zhuchen Li, Ying Wang, Junyi Ju, Alexander Nuber, Yupeng Wu, Ming Liu, Min Nie, Feifei Huang, Loretta Cerruti, Chi Ma, Renxiang Tan, Gunnar Schotta, Stephen M. Jane, Changjiang K. Zeng, Quan Zhao

Haematologica. 2016 May; 101(5): e168–e172. doi: 10.3324/haematol.2015.139980

PMCID:: PMC5004379

Article PDF–749K

Select item 403931011.

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

Jiannong Li, Keiryn Bennett, Alexey Stukalov, Bin Fang, Guolin Zhang, Takeshi Yoshida, Isamu Okamoto, Jae-Young Kim, Lanxi Song, Yun Bai, Xiaoning Qian, Bhupendra Rawal, Michael Schell, Florian Grebien, Georg Winter, Uwe Rix, Steven Eschrich, Jacques Colinge, John Koomen, Giulio Superti-Furga, Eric B Haura

Mol Syst Biol. 2013; 9: 705. Published online 2013 Nov 5. doi: 10.1038/msb.2013.61

PMCID:: PMC4039310

Abstract Article PDF–3.2M

Select item 383686612.

Transcriptional environment and chromatin architecture interplay dictates globin expression patterns of heterospecific hybrids derived from undifferentiated human embryonic stem cells or from their erythroid progeny

Kai-Hsin Chang, Andy Huang, Hemei Han, Yi Jiang, Xiangdong Fang, Chao-Zhong Song, Steve Padilla, Hao Wang, Hongzhu Qu, John Stamatoyannopoulos, Qiliang Li, Thalia Papayannopoulou

Exp Hematol. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Exp Hematol. 2013 Nov; 41(11): 10.1016/j.exphem.2013.08.005. Published online 2013 Aug 28. doi: 10.1016/j.exphem.2013.08.005

PMCID:: PMC3836866

Abstract Article PDF–2.8M

Select item 365747513.

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children

Jin Li, Joseph T. Glessner, Haitao Zhang, Cuiping Hou, Zhi Wei, Jonathan P. Bradfield, Frank D. Mentch, Yiran Guo, Cecilia Kim, Qianghua Xia, Rosetta M. Chiavacci, Kelly A. Thomas, Haijun Qiu, Struan F.A. Grant, Susan L. Furth, Hakon Hakonarson, Patrick M.A. Sleiman

Hum Mol Genet. 2013 Apr 1; 22(7): 1457–1464. Published online 2012 Dec 20. doi: 10.1093/hmg/dds534

PMCID:: PMC3657475

Abstract Article PDF–147K

Select item 347207414.

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment

Adam Byron, Jonathan D Humphries, Sue E Craig, David Knight, Martin J Humphries

Proteomics. 2012 Jul; 12(13): 2107–2114. Published online 2012 Jul 17. doi: 10.1002/pmic.201100487

PMCID:: PMC3472074

Abstract Article PDF–1.0M

Select item 331090015.

A TRANSGENIC MOUSE MODEL EXPRESSING EXCLUSIVELY HUMAN HEMOGLOBIN E: INDICATIONS OF A MILD OXIDATIVE STRESS

Qiuying Chen, Mary E. Fabry, Anne C. Rybicki, Sandra M. Suzuka, Tatiana C. Balazs, Zipora Etzion, Kitty de Jong, Edna K. Akoto, Joseph E. Canterino, Dhananjay K. Kaul, Frans A. Kuypers, David Lefer, Eric E. Bouhassira, Rhoda Elison Hirsch

Blood Cells Mol Dis. Author manuscript; available in PMC 2013 Feb 15.

Published in final edited form as: Blood Cells Mol Dis. 2012 Feb 15; 48(2): 91–101. Published online 2012 Jan 18. doi: 10.1016/j.bcmd.2011.12.002

PMCID:: PMC3310900

Abstract Article PDF–2.5M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311016517.

Effects of Chronic Ascariasis and Trichuriasis on Cytokine Production and Gene Expression in Human Blood: A Cross-Sectional Study

Miguel Reina Ortiz, Fernanda Schreiber, Susana Benitez, Nely Broncano, Martha E. Chico, Maritza Vaca, Neal Alexander, David J. Lewis, Gordon Dougan, Philip J. Cooper

PLoS Negl Trop Dis. 2011 Jun; 5(6): e1157. Published online 2011 Jun 7. doi: 10.1371/journal.pntd.0001157

PMCID:: PMC3110165

Abstract Article PDF–366K

Select item 296729718.

A large-scale candidate-gene association study of age at menarche and age at natural menopause

Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter

Hum Genet. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4

PMCID:: PMC2967297

Abstract Article PDF–84K

Select item 294414419.

Analysis of ^Gγ-158(C→T) polymorphism in hemoglobin E/β-thalassemia major in Southern China

Rong Rong Liu, Ming Yue Wang, Yong Rong Lai

J Hematol Oncol. 2010; 3: 29. Published online 2010 Sep 7. doi: 10.1186/1756-8722-3-29

PMCID:: PMC2944144

Abstract Article PDF–316K

Select item 286437620.

A mechanism of ineffective erythropoiesis in β-thalassemia/Hb E disease

Pathrapol Lithanatudom, Amporn Leecharoenkiat, Tirawat Wannatung, Saovaros Svasti, Suthat Fucharoen, Duncan R. Smith

Haematologica. 2010 May; 95(5): 716–723. Published online 2009 Dec 16. doi: 10.3324/haematol.2009.015701

PMCID:: PMC2864376

Abstract Article PDF–1.4M

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