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Select item 101516151.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 94754622.

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold

Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo

Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134

PMCID:: PMC9475462

Abstract Article PDF–4.6M

Select item 88970223.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 88747044.

Transcriptional Control of Trpm6 by the Nuclear Receptor FXR

Eun Young Kim, Jae Man Lee

Int J Mol Sci. 2022 Feb; 23(4): 1980. Published online 2022 Feb 10. doi: 10.3390/ijms23041980

PMCID:: PMC8874704

Abstract Article PDF–3.3M

Select item 83223965.

Evidence for the expression of TRPM6 and TRPM7 in cardiomyocytes from all four chamber walls of the human heart

Inga Andriulė, Dalia Pangonytė, Mantė Almanaitytė, Vaiva Patamsytė, Milda Kuprytė, Dainius Karčiauskas, Kanigula Mubagwa, Regina Mačianskienė

Sci Rep. 2021; 11: 15445. Published online 2021 Jul 29. doi: 10.1038/s41598-021-94856-4

PMCID:: PMC8322396

Abstract Article PDF–3.5M

Select item 67705776.

TRPM6 N-Terminal CaM- and S100A1-Binding Domains

Monika Zouharova, Petr Herman, Kateřina Hofbauerová, Jiri Vondrasek, Kristyna Bousova

Int J Mol Sci. 2019 Sep; 20(18): 4430. Published online 2019 Sep 9. doi: 10.3390/ijms20184430

PMCID:: PMC6770577

Abstract Article PDF–2.1M

Select item 65811977.

Gain of additional BIRC3 protein functions through 3′UTR-mediated protein complex formation

Shih-Han Lee, Christine Mayr

Mol Cell. Author manuscript; available in PMC 2020 May 16.

Published in final edited form as: Mol Cell. 2019 May 16; 74(4): 701–712.e9. Published online 2019 Apr 1. doi: 10.1016/j.molcel.2019.03.006

PMCID:: PMC6581197

Abstract Article PDF–2.0M

Select item 63610888.

Exome sequencing identifies a novel frameshift variant causing hypomagnesemia with secondary hypocalcemia

M. Kamran Azim, Aisha Mehnaz, Javeria Z. Ahmed, Ghulam Mujtaba

CEN Case Rep. 2019 Feb; 8(1): 42–47. Published online 2018 Aug 24. doi: 10.1007/s13730-018-0362-x

PMCID:: PMC6361088

Abstract Article PDF–1.2M

Select item 60243739.

TRPM6 is Essential for Magnesium Uptake and Epithelial Cell Function in the Colon

Francesca Luongo, Giuseppe Pietropaolo, Mathieu Gautier, Isabelle Dhennin-Duthille, Halima Ouadid-Ahidouch, Federica I. Wolf, Valentina Trapani

Nutrients. 2018 Jun; 10(6): 784. Published online 2018 Jun 18. doi: 10.3390/nu10060784

PMCID:: PMC6024373

Abstract Article PDF–2.7M

Select item 557682610.

Histone phosphorylation by TRPM6’s cleaved kinase attenuates adjacent arginine methylation to regulate gene expression

Grigory Krapivinsky, Luba Krapivinsky, Nora E. Renthal, Ana Santa-Cruz, Yunona Manasian, David E. Clapham

Proc Natl Acad Sci U S A. 2017 Aug 22; 114(34): E7092–E7100. Published online 2017 Aug 7. doi: 10.1073/pnas.1708427114

PMCID:: PMC5576826

Abstract Article PDF–1.7M

Select item 531898911.

Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases

Na Cai, Zhiyong Bai, Vikas Nanda, Loren W. Runnels

Sci Rep. 2017; 7: 42739. Published online 2017 Feb 21. doi: 10.1038/srep42739

PMCID:: PMC5318989

Abstract Article PDF–3.5M

Select item 480504012.

A Novel Homozygous Mutation in the Transient Receptor Potential Melastatin 6 Gene: A Case Report

Ayça Altıncık, Karl Peter Schlingmann, Mahya Sultan Tosun

J Clin Res Pediatr Endocrinol. 2016 Mar; 8(1): 101–104. Published online 2016 Mar 1. doi: 10.4274/jcrpe.2254

PMCID:: PMC4805040

Abstract Article PDF–126K

Select item 464331213.

Magnesium homeostasis in colon carcinoma LoVo cells sensitive or resistant to doxorubicin

Sara Castiglioni, Alessandra Cazzaniga, Valentina Trapani, Concettina Cappadone, Giovanna Farruggia, Lucia Merolle, Federica I. Wolf, Stefano Iotti, Jeanette A M Maier

Sci Rep. 2015; 5: 16538. Published online 2015 Nov 13. doi: 10.1038/srep16538

PMCID:: PMC4643312

Abstract Article PDF–793K

Select item 446207714.

Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study

Adrienne Tin, Anna Köttgen, Aaron R Folsom, Nisa M Maruthur, Salman M Tajuddin, Mike A Nalls, Michele K Evans, Alan B Zonderman, Christopher A Friedrich, Eric Boerwinkle, Josef Coresh, Wen Hong Linda Kao

BMC Genet. 2015; 16: 56. Published online 2015 May 29. doi: 10.1186/s12863-015-0219-7

PMCID:: PMC4462077

Abstract Article PDF–721K

Select item 423468315.

TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions

Katherine Brandao, Francina Deason-Towne, Xiaoyun Zhao, Anne-Laure Perraud, Carsten Schmitz

Cell Mol Life Sci. 2014 Dec; 71(24): 4853–4867. Published online 2014 May 25. doi: 10.1007/s00018-014-1647-7

PMCID:: PMC4234683

Abstract Article PDF–1.9M

Select item 420214916.

N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation

Zheng Zhang, Malika Faouzi, Junhao Huang, Dirk Geerts, Haijie Yu, Andrea Fleig, Reinhold Penner

Oncotarget. 2014 Sep; 5(17): 7625–7634. Published online 2014 Jul 31. doi: 10.18632/oncotarget.2283

PMCID:: PMC4202149

Abstract Article PDF–1.1M

Select item 401998417.

Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction

Jenny vanderWijst, Maxime G. Blanchard, Helen I. Woodroof, Thomas J. Macartney, Robert Gourlay, Joost G. Hoenderop, René J. Bindels, Dario R. Alessi

Biochem J. 2014 Jun 1; 460(Pt 2): 165–175. Prepublished online 2014 Mar 21. Published online 2014 May 13. doi: 10.1042/BJ20131639

PMCID:: PMC4019984

Abstract Article PDF–1.3M

Select item 395390518.

New TRPM6 missense mutations linked to hypomagnesemia with secondary hypocalcemia

Sergio Lainez, Karl Peter Schlingmann, Jenny van der Wijst, Bernd Dworniczak, Femke van Zeeland, Martin Konrad, René J Bindels, Joost G Hoenderop

Eur J Hum Genet. 2014 Apr; 22(4): 497–504. Published online 2013 Aug 14. doi: 10.1038/ejhg.2013.178

PMCID:: PMC3953905

Abstract Article PDF–1.2M

Select item 393107819.

The TRPM6 Kinase Domain Determines the Mg·ATP Sensitivity of TRPM7/M6 Heteromeric Ion Channels

Zheng Zhang, Haijie Yu, Junhao Huang, Malika Faouzi, Carsten Schmitz, Reinhold Penner, Andrea Fleig

J Biol Chem. 2014 Feb 21; 289(8): 5217–5227. Published online 2014 Jan 2. doi: 10.1074/jbc.M113.512285

PMCID:: PMC3931078

Abstract Article PDF–1.2M

Select item 339648220.

Loss of insulin-induced activation of TRPM6 magnesium channels results in impaired glucose tolerance during pregnancy

Anil V. Nair, Berthold Hocher, Sjoerd Verkaart, Femke van Zeeland, Thiemo Pfab, Torsten Slowinski, You-Peng Chen, Karl Peter Schlingmann, André Schaller, Sabina Gallati, René J. Bindels, Martin Konrad, Joost G. Hoenderop

Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28): 11324–11329. Published online 2012 Jun 25. doi: 10.1073/pnas.1113811109