PMC Links for GEO Profiles (Select 131140448) - PMC

Select item 105914951.

PKNOX1 acts as a transcription factor of DHH and promotes the progression of stomach adenocarcinoma by regulating the Hedgehog signalling pathway

Bing Liu, Siwei Zhao, Liqing Liu

Int J Immunopathol Pharmacol. 2023 Jan-Dec; 37: 03946320231208833. Published online 2023 Oct 21. doi: 10.1177/03946320231208833

PMCID:: PMC10591495

Abstract Article PDF–3.0M

Select item 83246152.

Mutations in the desert hedgehog (DHH) gene in the disorders of sexual differentiation and male infertility

Poonam Mehta, Priyamvada Singh, Nalini J. Gupta, Satya Narayan Sankhwar, Baidyanath Chakravarty, Kumarasamy Thangaraj, Singh Rajender

J Assist Reprod Genet. 2021 Jul; 38(7): 1871–1878. Published online 2021 Mar 12. doi: 10.1007/s10815-021-02140-1

PMCID:: PMC8324615

Abstract Article PDF–1.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67034904.

Desert Hedgehog Links Transcription Factor Sox10 to Perineurial Development

Melanie Küspert, Matthias Weider, Jana Müller, Irm Hermans-Borgmeyer, Dies Meijer, Michael Wegner

J Neurosci. 2012 Apr 18; 32(16): 5472–5480. doi: 10.1523/JNEUROSCI.5759-11.2012

PMCID:: PMC6703490

Abstract Article PDF–1.8M

Select item 65917405.

Functional analysis of novel desert hedgehog gene variants improves the clinical interpretation of genomic data and provides a more accurate diagnosis for patients with 46, XY differences of sex development

Katie Ayers, Jocelyn van den Bergen, Gorjana Robevska, Nurin Listyasari, Jamal Raza, Irum Atta, Stefan Riedl, Karen Rothacker, Catherine Choong, Sultana M H Faradz, Andrew Sinclair

J Med Genet. 2019 Jul; 56(7): 434–443. Published online 2019 Apr 24. doi: 10.1136/jmedgenet-2018-105893

PMCID:: PMC6591740

Abstract Article PDF–1.5M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 44903007.

46,XY Gonadal Dysgenesis due to a Homozygous Mutation in Desert Hedgehog (DHH) Identified by Exome Sequencing

Ralf Werner, Hartmut Merz, Wiebke Birnbaum, Louise Marshall, Tatjana Schröder, Benedikt Reiz, Jennifer M. Kavran, Tobias Bäumer, Philipp Capetian, Olaf Hiort

J Clin Endocrinol Metab. 2015 Jul; 100(7): E1022–E1029. Published online 2015 Apr 30. doi: 10.1210/jc.2015-1314

PMCID:: PMC4490300

Abstract Article

Select item 42694178.

A Genetic Variant in 12q13, a Possible Risk Factor for Bipolar Disorder, Is Associated with Depressive State, Accounting for Stressful Life Events

Ayu Shimasaki, Kenji Kondo, Takeo Saito, Kosei Esaki, Yasuyo Otsuka, Keiko Mano, Masashi Ikeda, Nakao Iwata

PLoS One. 2014; 9(12): e115135. Published online 2014 Dec 17. doi: 10.1371/journal.pone.0115135

PMCID:: PMC4269417

Abstract Article PDF–161K

Select item 42204169.

A new role for Hedgehogs in juxtacrine signaling

Christopher A. Pettigrew, Eva Asp, Charles P. Emerson, Jr.

Mech Dev. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Mech Dev. 2014 Feb; 131: 137–149. Published online 2013 Dec 14. doi: 10.1016/j.mod.2013.12.002

PMCID:: PMC4220416

Abstract Article PDF–1.1M

Select item 385855710.

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia

Riccardo Masetti, Marco Togni, Annalisa Astolfi, Martina Pigazzi, Elena Manara, Valentina Indio, Carmelo Rizzari, Sergio Rutella, Giuseppe Basso, Andrea Pession, Franco Locatelli

Oncotarget. 2013 Oct; 4(10): 1712–1720. Published online 2013 Sep 7. doi: 10.18632/oncotarget.1280

PMCID:: PMC3858557

Abstract Article PDF–1.2M

Select item 375312911.

In Vitro and Molecular Modeling Analysis of Two Mutant Desert Hedgehog Proteins Associated with 46,XY Gonadal Dysgenesis

Josué Joram Castro, Juan Pablo Méndez, Ramón Mauricio Coral-Vázquez, Marvin Antonio Soriano-Ursúa, Pablo Damian-Matsumura, Jesús Benítez-Granados, Haydee Rosas-Vargas, Patricia Canto

DNA Cell Biol. 2013 Sep; 32(9): 524–530. doi: 10.1089/dna.2013.2052

PMCID:: PMC3753129

Abstract Article PDF–352K

Select item 333886412.

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

Karol Estrada, Unnur Styrkarsdottir, Evangelos Evangelou, Yi-Hsiang Hsu, Emma L Duncan, Evangelia E Ntzani, Ling Oei, Omar M E Albagha, Najaf Amin, John P Kemp, Daniel L Koller, Guo Li, Ching-Ti Liu, Ryan L Minster, Alireza Moayyeri, Liesbeth Vandenput, Dana Willner, Su-Mei Xiao, Laura M Yerges-Armstrong, Hou-Feng Zheng, Nerea Alonso, Joel Eriksson, Candace M Kammerer, Stephen K Kaptoge, Paul J Leo, Gudmar Thorleifsson, Scott G Wilson, James F Wilson, Ville Aalto, Markku Alen, Aaron K Aragaki, Thor Aspelund, Jacqueline R Center, Zoe Dailiana, David J Duggan, Melissa Garcia, Natàlia Garcia-Giralt, Sylvie Giroux, Göran Hallmans, Lynne J Hocking, Lise Bjerre Husted, Karen A Jameson, Rita Khusainova, Ghi Su Kim, Charles Kooperberg, Theodora Koromila, Marcin Kruk, Marika Laaksonen, Andrea Z Lacroix, Seung Hun Lee, Ping C Leung, Joshua R Lewis, Laura Masi, Simona Mencej-Bedrac, Tuan V Nguyen, Xavier Nogues, Millan S Patel, Janez Prezelj, Lynda M Rose, Serena Scollen, Kristin Siggeirsdottir, Albert V Smith, Olle Svensson, Stella Trompet, Olivia Trummer, Natasja M van Schoor, Jean Woo, Kun Zhu, Susana Balcells, Maria Luisa Brandi, Brendan M Buckley, Sulin Cheng, Claus Christiansen, Cyrus Cooper, George Dedoussis, Ian Ford, Morten Frost, David Goltzman, Jesús González-Macías, Mika Kähönen, Magnus Karlsson, Elza Khusnutdinova, Jung-Min Koh, Panagoula Kollia, Bente Lomholt Langdahl, William D Leslie, Paul Lips, Östen Ljunggren, Roman S Lorenc, Janja Marc, Dan Mellström, Barbara Obermayer-Pietsch, José M Olmos, Ulrika Pettersson-Kymmer, David M Reid, José A Riancho, Paul M Ridker, François Rousseau, P Eline Slagboom, Nelson LS Tang, Roser Urreizti, Wim Van Hul, Jorma Viikari, María T Zarrabeitia, Yurii S Aulchenko, Martha Castano-Betancourt, Elin Grundberg, Lizbeth Herrera, Thorvaldur Ingvarsson, Hrefna Johannsdottir, Tony Kwan, Rui Li, Robert Luben, Carolina Medina-Gómez, Stefan Th Palsson, Sjur Reppe, Jerome I Rotter, Gunnar Sigurdsson, Joyce B J van Meurs, Dominique Verlaan, Frances MK Williams, Andrew R Wood, Yanhua Zhou, Kaare M Gautvik, Tomi Pastinen, Soumya Raychaudhuri, Jane A Cauley, Daniel I Chasman, Graeme R Clark, Steven R Cummings, Patrick Danoy, Elaine M Dennison, Richard Eastell, John A Eisman, Vilmundur Gudnason, Albert Hofman, Rebecca D Jackson, Graeme Jones, J Wouter Jukema, Kay-Tee Khaw, Terho Lehtimäki, Yongmei Liu, Mattias Lorentzon, Eugene McCloskey, Braxton D Mitchell, Kannabiran Nandakumar, Geoffrey C Nicholson, Ben A Oostra, Munro Peacock, Huibert A P Pols, Richard L Prince, Olli Raitakari, Ian R Reid, John Robbins, Philip N Sambrook, Pak Chung Sham, Alan R Shuldiner, Frances A Tylavsky, Cornelia M van Duijn, Nick J Wareham, L Adrienne Cupples, Michael J Econs, David M Evans, Tamara B Harris, Annie Wai Chee Kung, Bruce M Psaty, Jonathan Reeve, Timothy D Spector, Elizabeth A Streeten, M Carola Zillikens, Unnur Thorsteinsdottir, Claes Ohlsson, David Karasik, J Brent Richards, Matthew A Brown, Kari Stefansson, André G Uitterlinden, Stuart H Ralston, John P A Ioannidis, Douglas P Kiel, Fernando Rivadeneira

Nat Genet. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: Nat Genet. 2012 May; 44(5): 491–501. Published online 2012 Apr 15. doi: 10.1038/ng.2249