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Select item 97511141.

The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation

Emma J. Hunter, Samir W. Hamaia, Peter S.-K. Kim, Jean-Daniel M. Malcor, Richard W. Farndale

Sci Rep. 2022; 12: 21601. Published online 2022 Dec 14. doi: 10.1038/s41598-022-25937-1

PMCID:: PMC9751114

Abstract Article PDF–3.1M

Select item 92316232.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 87876423.

Erianin Controls Collagen-Mediated Retinal Angiogenesis via the RhoA/ROCK1 Signaling Pathway Induced by the alpha2/beta1 Integrin-Collagen Interaction

Xueke Li, Xiaoxue Liu, Yue Xing, Lingyan Zeng, Xin Liu, Huangxuan Shen, Jin Ma

Invest Ophthalmol Vis Sci. 2022 Jan; 63(1): 27. Published online 2022 Jan 21. doi: 10.1167/iovs.63.1.27

PMCID:: PMC8787642

Abstract Article PDF–20M

Select item 87487664.

The catalytic activity of TCPTP is auto-regulated by its intrinsically disordered tail and activated by Integrin alpha-1

Jai Prakash Singh, Yang Li, Yi-Yun Chen, Shang-Te Danny Hsu, Rebecca Page, Wolfgang Peti, Tzu-Ching Meng

Nat Commun. 2022; 13: 94. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27633-6

PMCID:: PMC8748766

Abstract Article PDF–3.5M

Select item 84622715.

CD49a Identifies Polyfunctional Memory CD8 T Cell Subsets that Persist in the Lungs After Influenza Infection

Emma C. Reilly, Mike Sportiello, Kris Lambert Emo, Andrea M. Amitrano, Rakshanda Jha, Ashwin B. R. Kumar, Nathan G. Laniewski, Hongmei Yang, Minsoo Kim, David J. Topham

Front Immunol. 2021; 12: 728669. Published online 2021 Sep 9. doi: 10.3389/fimmu.2021.728669

PMCID:: PMC8462271

Abstract Article PDF–3.4M

Select item 83641816.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74593618.

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease

Douglas. K. Brubaker, Manu. P. Kumar, Evan. L. Chiswick, Cecil Gregg, Alina Starchenko, Paige. N. Vega, Austin. N. Southard-Smith, Alan. J. Simmons, Elizabeth. A. Scoville, Lori. A. Coburn, Keith. T. Wilson, Ken. S. Lau, Douglas. A. Lauffenburger

Sci Signal. Author manuscript; available in PMC 2021 Feb 4.

Published in final edited form as: Sci Signal. 2020 Aug 4; 13(643): eaay3258. Published online 2020 Aug 4. doi: 10.1126/scisignal.aay3258

PMCID:: PMC7459361

Abstract Article PDF–2.1M

Select item 71479329.

Influence of collagen-based integrin α₁ and α₂ mediated signaling on human mesenchymal stem cell osteogenesis in three dimensional contexts

Silvia M. Becerra-Bayona, Viviana R. Guiza-Arguello, Brooke Russell, Magnus Höök, Mariah S. Hahn

J Biomed Mater Res A. Author manuscript; available in PMC 2020 Apr 10.

Published in final edited form as: J Biomed Mater Res A. 2018 Oct; 106(10): 2594–2604. Published online 2018 Sep 8. doi: 10.1002/jbm.a.36451

PMCID:: PMC7147932

Abstract Article PDF–556K

Select item 713164910.

310 Ribavirin coupled to hemoglobin protects against viral hepatitis induced by the corona virus MHV-3 in mice

Gary A. Levy, Anand Ghanekar, Ian McGilvray, Nancy F. Ng, Adam Levy, Laisum Fung, M.J. Phillips, Pieter Biessels, Caroline Woods, Gord Adamson, David N. Bell

Hepatology. 2003; 38: 305. Published online 2004 Nov 3. doi: 10.1016/S0270-9139(03)80353-1

PMCID:: PMC7131649

Abstract PDF–193K

Select item 678143011.

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier

Kuniyuki Nakamura, Tomoko Ikeuchi, Kazuki Nara, Craig S. Rhodes, Peipei Zhang, Yuta Chiba, Saiko Kazuno, Yoshiki Miura, Tetsuro Ago, Eri Arikawa-Hirasawa, Yoh-suke Mukouyama, Yoshihiko Yamada

J Cell Biol. 2019 Oct 7; 218(10): 3506–3525. Published online 2019 Sep 20. doi: 10.1083/jcb.201807178

PMCID:: PMC6781430

Abstract Article PDF–5.3M

Select item 661572812.

Magnesium Activates Microsecond Dynamics to Regulate Integrin-Collagen Recognition

Ana Monica Nunes, Conceição A.S.A. Minetti, David P. Remeta, Jean Baum

Structure. Author manuscript; available in PMC 2019 Jul 9.

Published in final edited form as: Structure. 2018 Aug 7; 26(8): 1080–1090.e5. Published online 2018 Jun 21. doi: 10.1016/j.str.2018.05.010

PMCID:: PMC6615728

Abstract Article PDF–1.9M

Select item 629804013.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 625176114.

Endogenous Cell Type-Specific DISC1 Interactomes Reveal Protein Networks Associated to Neurodevelopmental Disorders

Brent Wilkinson, Oleg Evgrafov, DongQing Zheng, Nicolas Hartel, James A. Knowles, Nicholas A. Graham, Justin Ichida, Marcelo P. Coba

Biol Psychiatry. Author manuscript; available in PMC 2020 Feb 15.

Published in final edited form as: Biol Psychiatry. 2019 Feb 15; 85(4): 305–316. Published online 2018 May 23. doi: 10.1016/j.biopsych.2018.05.009

PMCID:: PMC6251761

Abstract Article PDF–1.6M

Select item 605324715.

Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB

Janina Bruening, Lisa Lasswitz, Pia Banse, Sina Kahl, Carine Marinach, Florian W. Vondran, Lars Kaderali, Olivier Silvie, Thomas Pietschmann, Felix Meissner, Gisa Gerold

PLoS Pathog. 2018 Jul; 14(7): e1007111. Published online 2018 Jul 19. doi: 10.1371/journal.ppat.1007111

PMCID:: PMC6053247

Abstract Article PDF–8.7M

Select item 582692616.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 581844917.

IL‐12 and IL‐15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells

Theresa Hydes, Angela Noll, Gabriela Salinas‐Riester, Mohammed Abuhilal, Thomas Armstrong, Zaed Hamady, John Primrose, Arjun Takhar, Lutz Walter, Salim I. Khakoo

Immun Inflamm Dis. 2018 Mar; 6(1): 34–46. Published online 2017 Sep 27. doi: 10.1002/iid3.190

PMCID:: PMC5818449

Abstract Article PDF–1.4M

Select item 573361018.

A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding

Zhengli Wang, Aye Myat Myat Thinn, Jieqing Zhu

J Biol Chem. 2017 Dec 15; 292(50): 20756–20768. Published online 2017 Oct 27. doi: 10.1074/jbc.M117.790519

PMCID:: PMC5733610

Abstract Article PDF–3.7M

Select item 561172519.

The SNP-set based association study identifies ITGA1 as a susceptibility gene of attention-deficit/hyperactivity disorder in Han Chinese

L Liu, L Zhang, H M Li, Z R Wang, X F Xie, J P Mei, J L Jin, J Shi, L Sun, S C Li, Y L Tan, L Yang, J Wang, H M Yang, Q J Qian, Y F Wang

Transl Psychiatry. 2017 Aug; 7(8): e1201. Published online 2017 Aug 15. doi: 10.1038/tp.2017.156

PMCID:: PMC5611725

Abstract Article PDF–631K

Select item 557724820.

ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer

Armen Gharibi, Sa La Kim, Justin Molnar, Daniel Brambilla, Yvess Adamian, Malachia Hoover, Julie Hong, Joy Lin, Laurelin Wolfenden, Jonathan A. Kelber

Sci Rep. 2017; 7: 10060. Published online 2017 Aug 30. doi: 10.1038/s41598-017-09946-z

PMCID:: PMC5577248

Abstract Article PDF–8.6M

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