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Items: 1 to 20 of 35

1.
Dimeric transport mechanism of human vitamin C transporter SVCT1
Takaaki A. Kobayashi, Hiroto Shimada, Fumiya K. Sano, Yuzuru Itoh, Sawako Enoki, Yasushi Okada, Tsukasa Kusakizako, Osamu Nureki
Nat Commun. 2024; 15: 5569. Published online 2024 Jul 2. doi: 10.1038/s41467-024-49899-2
PMCID:
PMC11219872
AbstractArticlePDF–4.2M
2.
Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations
Yu Toyoda, Hiroshi Miyata, Naohiro Uchida, Keito Morimoto, Ryuichiro Shigesawa, Hidetoshi Kassai, Kazuki Nakao, Naoko H. Tomioka, Hirotaka Matsuo, Kimiyoshi Ichida, Makoto Hosoyamada, Atsu Aiba, Hiroshi Suzuki, Tappei Takada
Pflugers Arch. 2023; 475(4): 489–504. Published online 2023 Feb 7. doi: 10.1007/s00424-023-02792-1
PMCID:
PMC10011331
AbstractArticlePDF–1.0M
3.
Effects of functional variants of vitamin C transporter genes on apolipoprotein E E4-associated risk of cognitive decline: The Nakajima study
Koji Hayashi, Moeko Noguchi-Shinohara, Takehiro Sato, Kazuyoshi Hosomichi, Takayuki Kannon, Chiemi Abe, Chiaki Domoto, Sohshi Yuki-Nozaki, Ayaka Mori, Mai Horimoto, Masami Yokogawa, Kenji Sakai, Kazuo Iwasa, Kiyonobu Komai, Mai Ishimiya, Hiroyuki Nakamura, Natsuko Ishida, Yukio Suga, Junko Ishizaki, Akihito Ishigami, Atsushi Tajima, Masahito Yamada
PLoS One. 2021; 16(11): e0259663. Published online 2021 Nov 15. doi: 10.1371/journal.pone.0259663
PMCID:
PMC8592483
AbstractArticlePDF–781K
4.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
MicroRNA-103a regulates sodium-dependent vitamin C transporter-1 expression in intestinal epithelial cells
Veedamali S. Subramanian, Subrata Sabui, Jonathan S. Marchant, Hamid M. Said
J Nutr Biochem. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: J Nutr Biochem. 2019 Mar; 65: 46–53. Published online 2018 Dec 7. doi: 10.1016/j.jnutbio.2018.12.001
PMCID:
PMC6420349
AbstractArticlePDF–620K
7.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
8.
Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract
Veedamali S. Subramanian, Padmanabhan Srinivasan, Alexis J. Wildman, Jonathan S. Marchant, Hamid M. Said
Am J Physiol Gastrointest Liver Physiol. 2017 Apr 1; 312(4): G340–G347. Published online 2016 Dec 8. doi: 10.1152/ajpgi.00369.2016
PMCID:
PMC5407060
AbstractArticle
9.
Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants
Digna R. Velez, Stephen Fortunato, Poul Thorsen, Salvatore J. Lombardi, Scott M. Williams, Ramkumar Menon
Am J Obstet Gynecol. Author manuscript; available in PMC 2016 Apr 12.
Published in final edited form as: Am J Obstet Gynecol. 2009 Feb; 200(2): 209.e1–209.27. Published online 2008 Nov 18. doi: 10.1016/j.ajog.2008.08.051
PMCID:
PMC4829203
AbstractArticlePDF–164K
10.
Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with l-ascorbic acid
Kaitlin H Wade, Nita G Forouhi, Derek G Cook, Paul Johnson, Alex McConnachie, Richard W Morris, Santiago Rodriguez, Zheng Ye, Shah Ebrahim, Sandosh Padmanabhan, Graham Watt, K Richard Bruckdorfer, Nick J Wareham, Peter H Whincup, Stephen Chanock, Naveed Sattar, Debbie A Lawlor, George Davey Smith, Nicholas J Timpson
Am J Clin Nutr. 2015 Jan; 101(1): 202–209. Published online 2014 Nov 19. doi: 10.3945/ajcn.114.092981
PMCID:
PMC4266888
AbstractArticlePDF–208K
11.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
12.
N-terminal basolateral targeting signal unlikely acts alone for differential trafficking of membrane transporters in MDCK cells
Shiu-Ming Kuo, Li-Yuan Wang, Siyuan Yu, Christine E. Campbell, Sujith A. Valiyaparambil, Mark Rance, Kenneth M. Blumenthal
Biochemistry. Author manuscript; available in PMC 2014 Jul 30.
Published in final edited form as: Biochemistry. 2013 Jul 30; 52(30): 5103–5116. Published online 2013 Jul 18. doi: 10.1021/bi4005914
PMCID:
PMC3779144
AbstractArticlePDF–7.9M
13.
Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis
Veedamali S. Subramanian, Svetlana M. Nabokina, Joseph R. Patton, Jonathan S. Marchant, Hamid Moradi, Hamid M. Said
Am J Physiol Gastrointest Liver Physiol. 2013 Jun 15; 304(12): G1079–G1086. Published online 2013 Apr 18. doi: 10.1152/ajpgi.00090.2013
PMCID:
PMC3680717
AbstractArticle
14.
Genetic variation at the SLC23A1 locus is associated with circulating levels of L-ascorbic acid (Vitamin C). Evidence from 5 independent studies with over 15000 participants
Nicholas J Timpson, Nita G Forouhi, Marie-Jo Brion, Roger M Harbord, Derek G Cook, Paul Johnson, Alex McConnachie, Richard W Morris, Santiago Rodriguez, Jian’an Luan, Shah Ebrahim, Sandosh Padmanabhan, Graham Watt, K Richard Bruckdorfer, Wareham NJ, Peter H Whincup, Steve Chanock, Naveed Sattar, Debbie A Lawlor, George Davey Smith
Am J Clin Nutr. Author manuscript; available in PMC 2013 Mar 22.
Published in final edited form as: Am J Clin Nutr. 2010 Aug; 92(2): 375–382. Published online 2010 Jun 2. doi: 10.3945/ajcn.2010.29438
Correction in:
Am J Clin Nutr, volume 98 on page 253
PMCID:
PMC3605792
AbstractArticlePDF–786K
15.
Modulation of function of sodium-dependent vitamin C transporter 1 (SVCT1) by Rab8a in intestinal epithelial cells: Studies utilizing Caco-2 cells and Rab8a knockout mice
Veedamali S. Subramanian, Sandeep B. Subramanya, Abhisek Ghosal, Jonathan S. Marchant, Akihiro Harada, Hamid M. Said
Dig Dis Sci. Author manuscript; available in PMC 2014 Mar 1.
Published in final edited form as: Dig Dis Sci. 2013 Mar; 58(3): 641–649. Published online 2012 Sep 27. doi: 10.1007/s10620-012-2388-9
PMCID:
PMC3547156
AbstractArticlePDF–1.9M
16.
Genetic Variation in Sodium-Dependent Vitamin C Transporters SLC23A1 and SLC23A2 and Risk of Advanced Colorectal Adenoma
Hans Christian Erichsen, Ulrike Peters, Peter Eck, Robert Welch, Robert E. Schoen, Meredith Yeager, Mark Levine, Richard B. Hayes, Stephen Chanock
Nutr Cancer. Author manuscript; available in PMC 2012 Nov 6.
Published in final edited form as: Nutr Cancer. 2008; 60(5): 652–659. doi: 10.1080/01635580802033110
PMCID:
PMC3490215
AbstractArticlePDF–454K
17.
Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes
Lin T. Guey, Montserrat García-Closas, Cristiane Murta-Nascimento, Josep Lloreta, Laia Palencia, Manolis Kogevinas, Nathaniel Rothman, Gemma Vellalta, Malu Calle, Gaëlle Marenne, Adonina Tardón, Alfredo Carrato, Reina García-Closas, Consol Serra, Debra T Silverman, Stephen Chanock, Francisco X. Real, Núria Malats
Eur Urol. Author manuscript; available in PMC 2011 Nov 18.
Published in final edited form as: Eur Urol. 2010 Feb; 57(2): 283–292. Published online 2009 Aug 12. doi: 10.1016/j.eururo.2009.08.001
PMCID:
PMC3220186
AbstractArticlePDF–595K
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Promoter Analysis of the Human Ascorbic Acid Transporters SVCT1 & 2: Mechanisms of Adaptive Regulation in Liver Epithelial Cells
Jack C. Reidling, Stanley A. Rubin
J Nutr Biochem. Author manuscript; available in PMC 2012 Apr 1.
Published in final edited form as: J Nutr Biochem. 2011 Apr; 22(4): 344–350. Published online 2010 May 14. doi: 10.1016/j.jnutbio.2010.03.001
PMCID:
PMC2923671
AbstractArticlePDF–714K
20.
A Large-scale genetic association study of esophageal adenocarcinoma risk
Chen-yu Liu, Michael C. Wu, Feng Chen, Monica Ter-Minassian, Kofi Asomaning, Rihong Zhai, Zhaoxi Wang, Li Su, Rebecca S. Heist, Matthew H. Kulke, Xihong Lin, Geoffrey Liu, David C. Christiani
Carcinogenesis. 2010 Jul; 31(7): 1259–1263. Published online 2010 May 7. doi: 10.1093/carcin/bgq092
PMCID:
PMC2893800
AbstractArticlePDF–84K

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