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Items: 1 to 20 of 34

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis
Natalia J. Gurule, Kenneth C. Malcolm, Chelsea Harris, Jennifer R. Knapp, Brian P. O’Connor, Jazalle McClendon, William J. Janssen, Frank Fang Yao Lee, Caitlin Price, Jackson Osaghae-Nosa, Emily A. Wheeler, Christine M. McMahon, Eric M. Pietras, Daniel A. Pollyea, Scott Alper
Leukemia. 2023; 37(10): 2115–2124. Published online 2023 Aug 17. doi: 10.1038/s41375-023-02007-7
PMCID:
PMC10539173
AbstractArticlePDF–2.8M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
4.
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins
Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo
BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y
PMCID:
PMC8744257
AbstractArticlePDF–6.0M
5.
Mutant U2AF1-induced differential alternative splicing causes an oxidative stress in bone marrow stromal cells
Zhe Liu, Xuanjia Dong, Zhijie Cao, Shaowei Qiu, Yihui Li, Mengjun Zhong, Zhenya Xue, Yingxi Xu, Haiyan Xing, Kejing Tang, Zheng Tian, Min Wang, Qing Rao, Jianxiang Wang
Exp Biol Med (Maywood) 2021 Aug; 246(15): 1750–1759. Published online 2021 May 25. doi: 10.1177/15353702211010130
PMCID:
PMC8719038
AbstractArticlePDF–1.3M
6.
U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice
Brian A. Wadugu, Sridhar Nonavinkere Srivatsan, Amanda Heard, Michael O. Alberti, Matthew Ndonwi, Jie Liu, Sarah Grieb, Joseph Bradley, Jin Shao, Tanzir Ahmed, Cara L. Shirai, Ajay Khanna, Dennis L. Fei, Christopher A. Miller, Timothy A. Graubert, Matthew J. Walter
J Clin Invest. 2021 Nov 1; 131(21): e141401. Published online 2021 Nov 1. doi: 10.1172/JCI141401
PMCID:
PMC8553566
AbstractArticlePDF–5.4M
7.
Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
Sanghyun P. Kim, Sridhar N. Srivatsan, Monique Chavez, Cara L. Shirai, Brian S. White, Tanzir Ahmed, Michael O. Alberti, Jin Shao, Ryan Nunley, Lynn S. White, Jeff Bednarski, John R. Pehrson, Matthew J. Walter
Cell Rep. Author manuscript; available in PMC 2021 Sep 21.
Published in final edited form as: Cell Rep. 2021 Aug 31; 36(9): 109626. doi: 10.1016/j.celrep.2021.109626
PMCID:
PMC8454217
AbstractArticlePDF–1.7M
8.
U2af1 is required for survival and function of hematopoietic stem/progenitor cells
Avik Dutta, Yue Yang, Bao T. Le, Yifan Zhang, Omar Abdel-Wahab, Chongzhi Zang, Golam Mohi
Leukemia. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Leukemia. 2021 Aug; 35(8): 2382–2398. Published online 2021 Jan 7. doi: 10.1038/s41375-020-01116-x
PMCID:
PMC8283943
AbstractArticlePDF–2.7M
9.
Aberrant Alternative Splicing in U2af1/Tet2 Double Mutant Mice Contributes to Major Hematological Phenotypes
Cristina Martínez-Valiente, Cristian Garcia-Ruiz, Beatriz Rosón, Alessandro Liquori, Elisa González-Romero, Raúl Fernández-González, Isabel Gómez-Redondo, José Cervera, Alfonso Gutiérrez-Adán, Alejandra Sanjuan-Pla
Int J Mol Sci. 2021 Jul; 22(13): 6963. Published online 2021 Jun 28. doi: 10.3390/ijms22136963
PMCID:
PMC8269301
AbstractArticlePDF–5.4M
10.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton
Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622
PMCID:
PMC8098814
AbstractArticlePDF–7.7M
11.
mTOR-regulated U2af1 tandem exon splicing specifies transcriptome features for translational control
Jae-Woong Chang, Hsin-Sung Yeh, Meeyeon Park, Luke Erber, Jiao Sun, Sze Cheng, Alexander M Bui, Naima Ahmed Fahmi, Ryan Nasti, Rui Kuang, Yue Chen, Wei Zhang, Jeongsik Yong
Nucleic Acids Res. 2019 Nov 4; 47(19): 10373–10387. Published online 2019 Sep 3. doi: 10.1093/nar/gkz761
PMCID:
PMC6821156
AbstractArticlePDF–3.9M
12.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
13.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
14.
Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1
Dennis Liang Fei, Tao Zhen, Benjamin Durham, John Ferrarone, Tuo Zhang, Lisa Garrett, Akihide Yoshimi, Omar Abdel-Wahab, Robert K. Bradley, Paul Liu, Harold Varmus
Proc Natl Acad Sci U S A. 2018 Oct 30; 115(44): E10437–E10446. Published online 2018 Oct 15. doi: 10.1073/pnas.1812669115
PMCID:
PMC6217397
AbstractArticlePDF–1.7M
15.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
16.
U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3’ End Formation
Sung Mi Park, Jianhong Ou, Lynn Chamberlain, Tessa M. Simone, Huan Yang, Ching-Man Virbasius, Abdullah M. Ali, Lihua J. Zhu, Siddhartha Mukherjee, Azra Raza, Michael R. Green
Mol Cell. Author manuscript; available in PMC 2017 May 19.
Published in final edited form as: Mol Cell. 2016 May 19; 62(4): 479–490. Published online 2016 May 12. doi: 10.1016/j.molcel.2016.04.011
PMCID:
PMC5012111
AbstractArticlePDF–2.0M
17.
Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo
Cara Lunn Shirai, James N. Ley, Brian S. White, Sanghyun Kim, Justin Tibbitts, Jin Shao, Matthew Ndonwi, Brian Wadugu, Eric J. Duncavage, Theresa Okeyo-Owuor, Tuoen Liu, Malachi Griffith, Sean McGrath, Vincent Magrini, Robert S. Fulton, Catrina Fronick, Michelle O’Laughlin, Timothy A. Graubert, Matthew J. Walter
Cancer Cell. Author manuscript; available in PMC 2016 May 11.
Published in final edited form as: Cancer Cell. 2015 May 11; 27(5): 631–643. doi: 10.1016/j.ccell.2015.04.008
PMCID:
PMC4430854
AbstractArticlePDF–1.6M
18.
Dosage of the Abcg1-U2af1 Region Modifies Locomotor and Cognitive Deficits Observed in the Tc1 Mouse Model of Down Syndrome
Damien Marechal, Patricia Lopes Pereira, Arnaud Duchon, Yann Herault
PLoS One. 2015; 10(2): e0115302. Published online 2015 Feb 23. doi: 10.1371/journal.pone.0115302
PMCID:
PMC4338106
AbstractArticlePDF–496K
19.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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