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Select item 106540281.

O-GlcNAc has crosstalk with ADP-ribosylation via PARG

Jie Li, Xiangxiang Liu, Bin Peng, Tingting Feng, Wen Zhou, Li Meng, Shanshan Zhao, Xiyuan Zheng, Chen Wu, Shian Wu, Xing Chen, Xingzhi Xu, Jianwei Sun, Jing Li

J Biol Chem. 2023 Nov; 299(11): 105354. Published online 2023 Oct 17. doi: 10.1016/j.jbc.2023.105354

PMCID:: PMC10654028

Abstract Article PDF–2.1M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102383863.

Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling

Pietro Fontana, Sara C. Buch-Larsen, Osamu Suyari, Rebecca Smith, Marcin J. Suskiewicz, Kira Schützenhofer, Antonio Ariza, Johannes Gregor Matthias Rack, Michael L. Nielsen, Ivan Ahel

Nat Commun. 2023; 14: 3200. Published online 2023 Jun 2. doi: 10.1038/s41467-023-38793-y

PMCID:: PMC10238386

Abstract Article PDF–5.4M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 94917135.

FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

Hua Jiang, Weixiang Bian, Yue Sui, Huanle Li, Han Zhao, Wenqi Wang, Xu Li

Sci Adv. 2022 Sep; 8(38): eabq4831. Published online 2022 Sep 21. doi: 10.1126/sciadv.abq4831

PMCID:: PMC9491713

Abstract Article PDF–12M

Select item 94819336.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 92792857.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91052358.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 83191839.

Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal

Johannes Gregor Matthias Rack, Qiang Liu, Valentina Zorzini, Jim Voorneveld, Antonio Ariza, Kourosh Honarmand Ebrahimi, Julia M. Reber, Sarah C. Krassnig, Dragana Ahel, Gijsbert A. van der Marel, Aswin Mangerich, James S. O. McCullagh, Dmitri V. Filippov, Ivan Ahel

Nat Commun. 2021; 12: 4581. Published online 2021 Jul 28. doi: 10.1038/s41467-021-24723-3

PMCID:: PMC8319183

Abstract Article PDF–1.4M

Select item 822156710.

Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

Evgeniia Prokhorova, Thomas Agnew, Anne R. Wondisford, Michael Tellier, Nicole Kaminski, Danique Beijer, James Holder, Josephine Groslambert, Marcin J. Suskiewicz, Kang Zhu, Julia M. Reber, Sarah C. Krassnig, Luca Palazzo, Shona Murphy, Michael L. Nielsen, Aswin Mangerich, Dragana Ahel, Jonathan Baets, Roderick J. O’Sullivan, Ivan Ahel

Mol Cell. 2021 Jun 17; 81(12): 2640–2655.e8. doi: 10.1016/j.molcel.2021.04.028

PMCID:: PMC8221567

Abstract Article

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 803721112.

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective

Veronique Jonckheere, Petra Van Damme

Int J Mol Sci. 2021 Apr; 22(7): 3690. Published online 2021 Apr 1. doi: 10.3390/ijms22073690

PMCID:: PMC8037211

Abstract Article PDF–6.5M

Select item 797970513.

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1

Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu

NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3

PMCID:: PMC7979705

Abstract Article PDF–6.8M

Select item 792142314.

Cells recognize osmotic stress through liquid–liquid phase separation lubricated with poly(ADP-ribose)

Kengo Watanabe, Kazuhiro Morishita, Xiangyu Zhou, Shigeru Shiizaki, Yasuo Uchiyama, Masato Koike, Isao Naguro, Hidenori Ichijo

Nat Commun. 2021; 12: 1353. Published online 2021 Mar 1. doi: 10.1038/s41467-021-21614-5

PMCID:: PMC7921423

Abstract Article PDF–6.2M

Select item 791045915.

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams

Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9

PMCID:: PMC7910459

Abstract Article PDF–3.3M

Select item 780963516.

Regulation of ALT-associated homology-directed repair by polyADP-ribosylation

Song My Hoang, Nicole Kaminski, Ragini Bhargava, Jonathan Barroso-González, Michelle L. Lynskey, Laura García-Expósito, Justin L. Roncaioli, Anne R. Wondisford, Callen T. Wallace, Simon C. Watkins, Dominic I. James, Ian D. Waddell, Donald Ogilvie, Kate M. Smith, Felipe da Veiga Leprevost, Dattatreya Mellacharevu, Alexey I. Nesvizhskii, Jianfeng Li, Dominique Ray-Gallet, Robert W. Sobol, Genevieve Almouzni, Roderick J. O’Sullivan

Nat Struct Mol Biol. Author manuscript; available in PMC 2021 Jan 15.

Published in final edited form as: Nat Struct Mol Biol. 2020 Dec; 27(12): 1152–1164. Published online 2020 Oct 12. doi: 10.1038/s41594-020-0512-7

PMCID:: PMC7809635

Abstract Article PDF–2.0M

Select item 681650617.

Poly (ADP) ribose glycohydrolase can be effectively targeted in pancreatic cancer

Aditi Jain, Lebaron C. Agostini, Grace A. McCarthy, Saswati N. Chand, AnnJosette Ramirez, Avinoam Nevler, Joseph Cozzitorto, Christopher W. Schultz, Cinthya Yabar Lowder, Kate M. Smith, Ian D. Waddell, Maria Raitses-Gurevich, Chani Stossel, Yulia Glick Gorman, Dikla Atias, Charles J. Yeo, Jordan M. Winter, Kenneth P. Olive, Talia Golan, Michael J. Pishvaian, Donald Ogilvie, Dominic I. James, Allan M. Jordan, Jonathan R. Brody

Cancer Res. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Cancer Res. 2019 Sep 1; 79(17): 4491–4502. Published online 2019 Jul 4. doi: 10.1158/0008-5472.CAN-18-3645

PMCID:: PMC6816506

Abstract Article PDF–1.9M

Select item 648471118.

Oncogenic activity of poly (ADP-ribose) glycohydrolase

Maud Marques, Maika Jangal, Li-Chun Wang, Anna Kazanets, Sabrina Daniela da Silva, Tiejun Zhao, Amanda Lovato, Henry Yu, Su Jie, Sonia del Rincon, John Mackey, Sambasivarao Damaraju, Moulay Alaoui-Jamali, Michael Witcher

Oncogene. 2019; 38(12): 2177–2191. Published online 2018 Nov 20. doi: 10.1038/s41388-018-0568-6

PMCID:: PMC6484711

Abstract Article PDF–2.9M

Select item 586483219.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G. Weldatsadik, Tiina Öhman, Markku Varjosalo

Nat Commun. 2018; 9: 1188. Published online 2018 Mar 22. doi: 10.1038/s41467-018-03523-2

PMCID:: PMC5864832

Abstract Article PDF–4.5M

Select item 576615320.

A novel non-canonical PIP-box mediates PARG interaction with PCNA

Tanja Kaufmann, Irina Grishkovskaya, Anton A. Polyansky, Sebastian Kostrhon, Eva Kukolj, Karin M. Olek, Sebastien Herbert, Etienne Beltzung, Karl Mechtler, Thomas Peterbauer, Josef Gotzmann, Lijuan Zhang, Markus Hartl, Bojan Zagrovic, Kareem Elsayad, Kristina Djinovic-Carugo, Dea Slade

Nucleic Acids Res. 2017 Sep 19; 45(16): 9741–9759. Published online 2017 Jul 12. doi: 10.1093/nar/gkx604

PMCID:: PMC5766153

Abstract Article PDF–6.8M

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