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Items: 1 to 20 of 107

1.
Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells
Nicola Alessio, Wolfgang Bohn, Verena Rauchberger, Flavio Rizzolio, Marilena Cipollaro, Michael Rosemann, Martin Irmler, Johannes Beckers, Antonio Giordano, Umberto Galderisi
Cell Mol Life Sci. 2013 May; 70(9): 1637–1651. Published online 2013 Jan 31. doi: 10.1007/s00018-012-1224-x
PMCID:
PMC11113310
ArticlePDF–1008K
2.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
ArticlePDF–4.2M
3.
AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance
Angel S.N. Ng, Shibo Zhang, Victor C.Y. Mak, Yuan Zhou, Yin Yuen, Rakesh Sharma, Yiling Lu, Guanglei Zhuang, Wei Zhao, Herbert H. Pang, Lydia W.T. Cheung
Cell Rep. Author manuscript; available in PMC 2023 Jan 13.
Published in final edited form as: Cell Rep. 2022 Dec 13; 41(11): 111821. doi: 10.1016/j.celrep.2022.111821
PMCID:
PMC9837615
ArticlePDF–3.0M
4.
Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells
Shota Nakanoh, Juned Kadiwala, Laetitia Pinte, Carola Maria Morell, An-Sofie Lenaerts, Ludovic Vallier
PLoS One. 2022; 17(11): e0269122. Published online 2022 Nov 22. doi: 10.1371/journal.pone.0269122
PMCID:
PMC9681086
ArticlePDF–2.2M
5.
Combined alteration of lamin and nuclear morphology influences the localization of the tumor-associated factor AKTIP
Mattia La Torre, Chiara Merigliano, Klizia Maccaroni, Alexandre Chojnowski, Wah Ing Goh, Maria Giubettini, Fiammetta Vernì, Cristina Capanni, Daniela Rhodes, Graham Wright, Brian Burke, Silvia Soddu, Romina Burla, Isabella Saggio
J Exp Clin Cancer Res. 2022; 41: 273. Published online 2022 Sep 13. doi: 10.1186/s13046-022-02480-5
PMCID:
PMC9469526
ArticlePDF–7.5M
6.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
ArticlePDF–3.0M
7.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
ArticlePDF–2.5M
8.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
ArticlePDF–3.3M
9.
Mutations in the acetylation hotspots of Rbl2 are associated with increased risk of breast cancer
Farman Ullah, Nadia Khurshid, Qaiser Fatimi, Peter Loidl, Muhammad Saeed
PLoS One. 2022; 17(4): e0266196. Published online 2022 Apr 6. doi: 10.1371/journal.pone.0266196
PMCID:
PMC8985964
ArticlePDF–3.5M
10.
Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS–Hook–FHIP complexes
Jenna R Christensen, Agnieszka A Kendrick, Joey B Truong, Adriana Aguilar-Maldonado, Vinit Adani, Monika Dzieciatkowska, Samara L Reck-Peterson
eLife. 2021; 10: e74538. Published online 2021 Dec 9. doi: 10.7554/eLife.74538
PMCID:
PMC8730729
ArticlePDF–14M
11.
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody
Chiara Merigliano, Romina Burla, Mattia La Torre, Simona Del Giudice, Hsiangling Teo, Chong Wai Liew, Alexandre Chojnowski, Wah Ing Goh, Yolanda Olmos, Klizia Maccaroni, Maria Giubettini, Irene Chiolo, Jeremy G. Carlton, Domenico Raimondo, Fiammetta Vernì, Colin L. Stewart, Daniela Rhodes, Graham D. Wright, Brian E. Burke, Isabella Saggio
PLoS Genet. 2021 Aug; 17(8): e1009757. Published online 2021 Aug 27. doi: 10.1371/journal.pgen.1009757
PMCID:
PMC8428793
ArticlePDF–4.7M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
ArticlePDF–2.2M
13.
Mutation of SPINOPHILIN (PPP1R9B) found in human tumors promotes the tumorigenic and stemness properties of cells
Eva M Verdugo-Sivianes, Ana M Rojas, Sandra Muñoz-Galván, Daniel Otero-Albiol, Amancio Carnero
Theranostics. 2021; 11(7): 3452–3471. Published online 2021 Jan 19. doi: 10.7150/thno.53572
PMCID:
PMC7847670
ArticlePDF–3.3M
14.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
ArticlePDF–4.8M
15.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
Article
16.
The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A
Rafael Mattera, Chad D. Williamson, Xuefeng Ren, Juan S. Bonifacino
Mol Biol Cell. 2020 Apr 15; 31(9): 963–979. doi: 10.1091/mbc.E19-11-0658
PMCID:
PMC7185972
ArticlePDF–3.9M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
ArticlePDF–5.4M
18.
Biallelic loss‐of‐function variants in RBL2 in siblings with a neurodevelopmental disorder
Theresa Brunet, Milena Radivojkov‐Blagojevic, Peter Lichtner, Verena Kraus, Thomas Meitinger, Matias Wagner
Ann Clin Transl Neurol. 2020 Mar; 7(3): 390–396. Published online 2020 Feb 27. doi: 10.1002/acn3.50992
PMCID:
PMC7086002
ArticlePDF–3.4M
19.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
ArticlePDF–1.2M
20.
The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb
Audra N. Iness, Jessica Felthousen, Varsha Ananthapadmanabhan, Fatmata Sesay, Siddharth Saini, Keelan Z. Guiley, Seth M. Rubin, Mikhail Dozmorov, Larisa Litovchick
Oncogene. Author manuscript; available in PMC 2019 Mar 11.
Published in final edited form as: Oncogene. 2019 Feb; 38(7): 1080–1092. Published online 2018 Sep 11. doi: 10.1038/s41388-018-0490-y
PMCID:
PMC6377300
ArticlePDF–1.1M

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