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Select item 112180431.

Hypoxia, Hypoxia-Inducible Gene 2 (HIG2)/HILPDA, and Intracellular Lipolysis in Cancer

Davide Povero, Scott M. Johnson, Jun Liu

Cancer Lett. Author manuscript; available in PMC 2024 Jul 2.

Published in final edited form as: Cancer Lett. 2020 Nov 28; 493: 71–79. Published online 2020 Aug 18. doi: 10.1016/j.canlet.2020.06.013

PMCID:: PMC11218043

Abstract Article PDF–770K

Select item 107426612.

Association between Polymorphism rs61876744 in PNPLA2 Gene and Keratoconus in a Saudi Cohort

Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Tanvir Khatlani, Abdulaziz A. Alshehri, Glenn P. Lobo, Hatem Kalantan, Saleh A. Al-Obeidan, Abdulrahman M. Al-Muammar

Genes (Basel) 2023 Dec; 14(12): 2108. Published online 2023 Nov 21. doi: 10.3390/genes14122108

PMCID:: PMC10742661

Abstract Article PDF–728K

Select item 104446293.

CLINICAL AND GENETIC ANALYSIS OF LIPID STORAGE MYOPATHIES

AYA OHKUMA, SATORU NOGUCHI, HIDEO SUGIE, MAY CHRISTINE V. MALICDAN, TOKIKO FUKUDA, KUNIO SHIMAZU, LUIS CARLOS LÓPEZ, MICHIO HIRANO, YUKIKO K. HAYASHI, IKUYA NONAKA, ICHIZO NISHINO

Muscle Nerve. Author manuscript; available in PMC 2023 Aug 23.

Published in final edited form as: Muscle Nerve. 2009 Mar; 39(3): 333–342. doi: 10.1002/mus.21167

PMCID:: PMC10444629

Abstract Article PDF–2.2M

Select item 98172444.

BETi enhance ATGL expression and its lipase activity to exert their antitumoral effects in triple-negative breast cancer (TNBC) cells

Teresa Rossi, Raffaella Zamponi, Mattea Chirico, Maria Elena Pisanu, Egidio Iorio, Federica Torricelli, Mila Gugnoni, Alessia Ciarrocchi, Mariaelena Pistoni

J Exp Clin Cancer Res. 2023; 42: 7. Published online 2023 Jan 6. doi: 10.1186/s13046-022-02571-3

PMCID:: PMC9817244

Abstract Article PDF–11M

Select item 92626145.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 92428546.

ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids

Rucha Patel, Anna Santoro, Peter Hofer, Dan Tan, Monika Oberer, Andrew T. Nelson, Srihari Konduri, Dionicio Siegel, Rudolf Zechner, Alan Saghatelian, Barbara B. Kahn

Nature. 2022; 606(7916): 968–975. Published online 2022 Jun 8. doi: 10.1038/s41586-022-04787-x

PMCID:: PMC9242854

Abstract Article PDF–12M

Select item 86881457.

Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis

Lianggong Ding, Wenfei Sun, Miroslav Balaz, Anyuan He, Manuel Klug, Stefan Wieland, Robert Caiazzo, Violeta Raverdy, Francois Pattou, Philippe Lefebvre, Irfan J. Lodhi, Bart Staels, Markus Heim, Christian Wolfrum

Nat Metab. 2021; 3(12): 1648–1661. Published online 2021 Dec 13. doi: 10.1038/s42255-021-00489-2

PMCID:: PMC8688145

Abstract Article PDF–25M

Select item 83866278.

Burkholderia pseudomallei interferes with host lipid metabolism via NR1D2-mediated PNPLA2/ATGL suppression to block autophagy-dependent inhibition of infection

Mengling Tang, Zhiqiang Hu, Chenglong Rao, Jiangao Chen, Siqi Yuan, Jiangang Zhang, Chan Mao, Jingmin Yan, Yupei Xia, Meijuan Zhang, Juanjuan Yue, Yang Xiang, Jianping Xie, Xuhu Mao, Qian Li

Autophagy. 2021; 17(8): 1918–1933. Published online 2020 Aug 11. doi: 10.1080/15548627.2020.1801270

PMCID:: PMC8386627

Abstract Article PDF–15M

Select item 82170889.

Loss of Ephrin B2 Receptor (EPHB2) Sets Lipid Rheostat by Regulating Proteins DGAT1 and ATGL Inducing Lipid Droplet Storage in Prostate Cancer Cells

Alejandro Morales, Max Greenberg, Francesca Nardi, Victoria Gil, Simon W. Hayward, Susan E. Crawford, Omar E. Franco

Lab Invest. Author manuscript; available in PMC 2021 Oct 6.

Published in final edited form as: Lab Invest. 2021 Jul; 101(7): 921–934. Published online 2021 Apr 6. doi: 10.1038/s41374-021-00583-9

PMCID:: PMC8217088

Abstract Article PDF–1.8M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 805171411.

Adipose triglyceride lipase promotes the proliferation of colorectal cancer cells via enhancing the lipolytic pathway

Haofan Yin, Wentao Li, Laiming Mo, Shaotuan Deng, Weijia Lin, Caiqi Ma, Zhaofan Luo, Chuanghua Luo, Honghai Hong

J Cell Mol Med. 2021 Apr; 25(8): 3963–3975. Published online 2021 Feb 23. doi: 10.1111/jcmm.16349

PMCID:: PMC8051714

Abstract Article PDF–2.5M

Select item 771895812.

Downregulation of adipose triglyceride lipase by EB viral‐encoded LMP2A links lipid accumulation to increased migration in nasopharyngeal carcinoma

Shixing Zheng, Liudmila Matskova, Xiaoying Zhou, Xue Xiao, Guangwu Huang, Zhe Zhang, Ingemar Ernberg

Mol Oncol. 2020 Dec; 14(12): 3234–3252. Published online 2020 Nov 8. doi: 10.1002/1878-0261.12824

PMCID:: PMC7718958

Abstract Article PDF–7.1M

Select item 765949213.

The Role of Adipose Triglyceride Lipase and Cytosolic Lipolysis in Cardiac Function and Heart Failure

Ulrich Kintscher, Anna Foryst-Ludwig, Guenter Haemmerle, Rudolf Zechner

Cell Rep Med. 2020 Apr 21; 1(1): 100001. Published online 2020 Mar 25. doi: 10.1016/j.xcrm.2020.100001

PMCID:: PMC7659492

Abstract Article PDF–2.0M

Select item 760717414.

Rho‐associated protein kinase‐dependent moesin phosphorylation is required for PD‐L1 stabilization in breast cancer

Fanbiao Meng, Yang Su, Bo Xu

Mol Oncol. 2020 Nov; 14(11): 2701–2712. Published online 2020 Oct 3. doi: 10.1002/1878-0261.12804

PMCID:: PMC7607174

Abstract Article PDF–4.2M

Select item 739747115.

Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling

Hao Xie, Christoph Heier, Benedikt Kien, Paul W. Vesely, Zhiyuan Tang, Veronika Sexl, Gabriele Schoiswohl, Isabelle Strießnig-Bina, Gerald Hoefler, Rudolf Zechner, Martina Schweiger

Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep; 1865(9): 158737. doi: 10.1016/j.bbalip.2020.158737

PMCID:: PMC7397471

Abstract Article

Select item 735212016.

Association between PNPLA2 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in a Chinese Han Population with Type 2 Diabetes

Hailing Zhao, Haojun Zhang, Yan Wang, Tingting Zhao, Meihua Yan, Xi Dong, Qian Wang, Jialin Li, Liang Ma, Ping Li

J Diabetes Res. 2020; 2020: 5424701. Published online 2020 Jun 30. doi: 10.1155/2020/5424701

PMCID:: PMC7352120

Abstract Article PDF–378K

Select item 731634517.

The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly

Gabrielle Vieyres, Isabelle Reichert, Arnaud Carpentier, Florian W. R. Vondran, Thomas Pietschmann

PLoS Pathog. 2020 Jun; 16(6): e1008554. Published online 2020 Jun 15. doi: 10.1371/journal.ppat.1008554

PMCID:: PMC7316345

Abstract Article PDF–8.5M

Select item 687481718.

The role of adipose triglyceride lipase in lipid and glucose homeostasis: lessons from transgenic mice

Michael J. Trites, Robin D. Clugston

Lipids Health Dis. 2019; 18: 204. Published online 2019 Nov 22. doi: 10.1186/s12944-019-1151-z

PMCID:: PMC6874817

Abstract Article PDF–546K

Select item 675611019.

Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-α/p300-mediated acetylation of p53

Luca Di Leo, Rolando Vegliante, Fabio Ciccarone, Illari Salvatori, Manuel Scimeca, Elena Bonanno, Andrea Sagnotta, Gian Luca Grazi, Katia Aquilano, Maria Rosa Ciriolo

Oncogene. 2019; 38(11): 1860–1875. Published online 2018 Oct 26. doi: 10.1038/s41388-018-0545-0

PMCID:: PMC6756110

Abstract Article PDF–1.7M

Select item 654763820.

PNPLA2 influences secretion of triglyceride-rich lipoproteins by human hepatoma cells

Apostolos Taxiarchis, Hovsep Mahdessian, Angela Silveira, Rachel M. Fisher, Ferdinand M. van’t Hooft

J Lipid Res. 2019 Jun; 60(6): 1069–1077. Published online 2019 Mar 27. doi: 10.1194/jlr.M090928

PMCID:: PMC6547638

Abstract Article PDF–1.5M

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