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Items: 1 to 20 of 28

1.
FGL1: a novel biomarker and target for non-small cell lung cancer, promoting tumor progression and metastasis through KDM4A/STAT3 transcription mechanism
Tian Yao Liu, Jin Shan Yan, Xin Li, Lu Xu, Jun Li Hao, Su Ya Zhao, Qi Lin Hu, Fang Jian Na, He Ming Li, Yue Zhao, Ming Fang Zhao
J Exp Clin Cancer Res. 2024; 43: 213. Published online 2024 Aug 1. doi: 10.1186/s13046-024-03140-6
PMCID:
PMC11293164
AbstractArticlePDF–12M
2.
The liver microenvironment orchestrates FGL1-mediated immune escape and progression of metastatic colorectal cancer
Jia-Jun Li, Jin-Hong Wang, Tian Tian, Jia Liu, Yong-Qiang Zheng, Hai-Yu Mo, Hui Sheng, Yan-Xing Chen, Qi-Nian Wu, Yi Han, Kun Liao, Yi-Qian Pan, Zhao-Lei Zeng, Ze-Xian Liu, Wei Yang, Rui-Hua Xu, Huai-Qiang Ju
Nat Commun. 2023; 14: 6690. Published online 2023 Oct 23. doi: 10.1038/s41467-023-42332-0
PMCID:
PMC10593839
AbstractArticlePDF–4.9M
3.
The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4
Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang
Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5
PMCID:
PMC10460732
AbstractArticlePDF–5.6M
4.
Fibrinogen-like protein 1 promotes liver-resident memory T-cell exhaustion in hepatocellular carcinoma
Changjie Yang, Qiwei Qian, Yudong Zhao, Bingyuan Huang, Ruilin Chen, Qiyu Gong, Hao Ji, Chenchen Wang, Lei Xia, Zhengrui You, Jianjun Zhang, Xiaosong Chen
Front Immunol. 2023; 14: 1112672. Published online 2023 Mar 13. doi: 10.3389/fimmu.2023.1112672
PMCID:
PMC10040674
AbstractArticlePDF–7.5M
5.
FGL1 as a modulator of plasma D-dimer levels: exome-wide marker analysis of plasma tPA, PAI-1 and D-dimer
Florian Thibord, Ci Song, Jack Pattee, Benjamin A.T. Rodriguez, Ming-Huei Chen, Christopher J. O’Donnell, Marcus E. Kleber, Graciela E. Delgado, Xiuqing Guo, Jie Yao, Kent D. Taylor, Ayse Bilge Ozel, Jennifer A. Brody, Barbara McKnight, Beata Gyorgy, Eleanor Simonsick, Hampton L. Leonard, Germán D. Carrasquilla, Marta Guindo-Martínez, Angela Silveira, Gerard Temprano-Sagrera, Lisa R. Yanek, Diane M. Becker, Rasika A. Mathias, Lewis C. Becker, Laura M. Raffield, Tuomas O. Kilpeläinen, Niels Grarup, Oluf Pedersen, Torben Hansen, Allan Linneberg, Anders Hamsten, Hugh Watkins, Maria Sabater-Lleal, Mike A. Nalls, David-Alexandre Trégouët, Pierre-Emmanuel Morange, Bruce M. Psaty, Russel P. Tracy, Nicholas L. Smith, Karl C. Desch, Mary Cushman, Jerome I. Rotter, Paul S. de Vries, Nathan D. Pankratz, Aaron R. Folsom, Alanna C. Morrison, Winfried März, Weihong Tang, Andrew D. Johnson
J Thromb Haemost. Author manuscript; available in PMC 2023 Feb 22.
Published in final edited form as: J Thromb Haemost. 2021 Aug; 19(8): 2019–2028. Published online 2021 May 30. doi: 10.1111/jth.15345
PMCID:
PMC9946195
AbstractArticlePDF–345K
6.
Dual immunological and proliferative regulation of immune checkpoint FGL1 in lung adenocarcinoma: The pivotal role of the YY1–FGL1–MYH9 axis
Xi-Yang Tang, Yan-Lu Xiong, Ya-Bo Zhao, Jie Yang, An-Ping Shi, Kai-Fu Zheng, Yu-Jian Liu, Chen Shu, Tao Jiang, Nan Ma, Jin-Bo Zhao
Front Immunol. 2022; 13: 1014053. Published online 2022 Oct 4. doi: 10.3389/fimmu.2022.1014053
PMCID:
PMC9577086
AbstractArticlePDF–15M
7.
Engineered Small Extracellular Vesicles as a FGL1/PD‐L1 Dual‐Targeting Delivery System for Alleviating Immune Rejection
Hsiang‐i Tsai, Yingyi Wu, Xiaoyan Liu, Zhanxue Xu, Longshan Liu, Changxi Wang, Huanxi Zhang, Yisheng Huang, Linglu Wang, Weixian Zhang, Dandan Su, Fahim Ullah Khan, Xiaofeng Zhu, Rongya Yang, Yuxin Pang, John E. Eriksson, Haitao Zhu, Dongqing Wang, Bo Jia, Fang Cheng, Hongbo Chen
Adv Sci (Weinh) 2022 Jan; 9(3): 2102634. Published online 2021 Nov 5. doi: 10.1002/advs.202102634
PMCID:
PMC8787398
AbstractArticlePDF–5.6M
8.
Proteomics identifies a novel role of fibrinogen-like protein 1 in Crohn’s disease
Xue-Liang Sun, Li-Chao Qiao, Jing Gong, Ke Wen, Zhi-Zhong Xu, Bo-Lin Yang
World J Gastroenterol. 2021 Sep 21; 27(35): 5946–5957. Published online 2021 Sep 21. doi: 10.3748/wjg.v27.i35.5946
PMCID:
PMC8475002
AbstractArticlePDF–6.9M
9.
Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target
Wenjing Qian, Mingfang Zhao, Ruoyu Wang, Heming Li
J Hematol Oncol. 2021; 14: 147. Published online 2021 Sep 15. doi: 10.1186/s13045-021-01161-8
PMCID:
PMC8444356
AbstractArticlePDF–4.6M
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
Fibrinogen-Like Protein 1 Modulates Sorafenib Resistance in Human Hepatocellular Carcinoma Cells
Yeonghoon Son, Na-Rae Shin, Sung-Ho Kim, Su-Cheol Park, Hae-June Lee
Int J Mol Sci. 2021 May; 22(10): 5330. Published online 2021 May 19. doi: 10.3390/ijms22105330
PMCID:
PMC8158706
AbstractArticlePDF–1.8M
12.
Eicosapentaenoic Acid Inhibits KRAS Mutant Pancreatic Cancer Cell Growth by Suppressing Hepassocin Expression and STAT3 Phosphorylation
Ching-Feng Chiu, Ming-I Hsu, Hsiu-Yen Yeh, Ji Min Park, Yu-Shiuan Shen, Te-Hsuan Tung, Jun-Jie Huang, Hung-Tsung Wu, Shih-Yi Huang
Biomolecules. 2021 Mar; 11(3): 370. Published online 2021 Mar 2. doi: 10.3390/biom11030370
PMCID:
PMC8001293
AbstractArticlePDF–2.9M
13.
Circulating hepassocin level in patients with stable angina is associated with fatty liver and renal function
I-Ting Tsai, Wei-Chin Hung, Yung-Chuan Lu, Cheng-Ching Wu, Thung-Lip Lee, Chin-Feng Hsuan, Teng-Hung Yu, Ching-Ting Wei, Fu-Mei Chung, Yau-Jiunn Lee, Chao-Ping Wang
Int J Med Sci. 2021; 18(1): 1–7. Published online 2021 Jan 1. doi: 10.7150/ijms.50646
PMCID:
PMC7738965
AbstractArticlePDF–465K
14.
Fibrinogen-Like Protein 1 Is a Novel Biomarker for Predicting Disease Activity and Prognosis of Rheumatoid Arthritis
Shijia Liu, Yunke Guo, Lu Lu, Jiawei Lu, Mengying Ke, Tingting Xu, Yan Lu, Wenjun Chen, Jue Wang, Deshun Kong, Qiuxiang Shen, Youjuan Zhu, WenFeng Tan, Wei Ji, Wei Zhou
Front Immunol. 2020; 11: 579228. Published online 2020 Oct 6. doi: 10.3389/fimmu.2020.579228
PMCID:
PMC7574527
AbstractArticlePDF–1.8M
15.
FGL1 regulates acquired resistance to Gefitinib by inhibiting apoptosis in non-small cell lung cancer
Cuilan Sun, Weiwei Gao, Jiatao Liu, Hao Cheng, Jiqing Hao
Respir Res. 2020; 21: 210. Published online 2020 Aug 10. doi: 10.1186/s12931-020-01477-y
PMCID:
PMC7418324
AbstractArticlePDF–2.7M
16.
Fibrinogen-like protein 1 is a major immune inhibitory ligand of LAG3
Jun Wang, Miguel F. Sanmamed, Ila Datar, Tina Tianjiao Su, Lan Ji, Jingwei Sun, Ling Chen, Yusheng Chen, Gefeng Zhu, Weiwei Yin, Linghua Zheng, Ting Zhou, Ti Badri, Sheng Yao, Shu Zhu, Agedi Boto, Mario Sznol, Ignacio Melero, Dario A. A. Vignali, Kurt Schalper, Lieping Chen
Cell. Author manuscript; available in PMC 2020 Jan 10.
Published in final edited form as: Cell. 2019 Jan 10; 176(1-2): 334–347.e12. Published online 2018 Dec 20. doi: 10.1016/j.cell.2018.11.010
PMCID:
PMC6365968
AbstractArticlePDF–2.5M
17.
Fibrinogen-like-protein 1 promotes the invasion and metastasis of gastric cancer and is associated with poor prognosis
Yang Zhang, Hui-Xia Qiao, Yong-Tao Zhou, Liang Hong, Ju-Hui Chen
Mol Med Rep. 2018 Aug; 18(2): 1465–1472. Published online 2018 May 29. doi: 10.3892/mmr.2018.9097
PMCID:
PMC6072172
AbstractArticlePDF–1.2M
18.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
19.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
20.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M

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