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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis
Shiue-Wei Lai, Yi-Chiao Cheng, Wen-Chien Huang, Vijesh Kumar Yadav, Iat-Hang Fong, Chi-Tai Yeh, Ching-Kuo Yang, Wei-Hwa Lee, Ming-Yao Chen
Aging (Albany NY) 2023 Oct 31; 15(20): 11033–11051. Published online 2023 Oct 13. doi: 10.18632/aging.205064
PMCID:
PMC10637823
AbstractArticlePDF–2.1M
3.
Slingshot homolog-1–mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer’s disease
Sara Cazzaro, Jung-A A. Woo, Xinming Wang, Tian Liu, Shanon Rego, Teresa R. Kee, Yeojung Koh, Edwin Vázquez-Rosa, Andrew A. Pieper, David E. Kang
Proc Natl Acad Sci U S A. 2023 Jul 25; 120(30): e2217128120. Published online 2023 Jul 18. doi: 10.1073/pnas.2217128120
PMCID:
PMC10374160
AbstractArticlePDF–16M
4.
Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics
Sara Cazzaro, Cenxiao Fang, Hirah Khan, Richard Witas, Teresa R. Kee, Jung-A. A. Woo, David E. Kang
Front Aging Neurosci. 2022; 14: 933979. Published online 2022 Aug 25. doi: 10.3389/fnagi.2022.933979
PMCID:
PMC9452914
AbstractArticlePDF–9.7M
5.
SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation
Cenxiao Fang, Jung-A A. Woo, Tian Liu, Xingyu Zhao, Sara Cazzaro, Yan Yan, Jenet Matlack, Teresa Kee, Patrick LePochat, David E. Kang
Autophagy. 2021; 17(9): 2144–2165. Published online 2020 Oct 12. doi: 10.1080/15548627.2020.1816663
PMCID:
PMC8496729
AbstractArticlePDF–14M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics
Joel M. Brown, María J. García-García
Development. 2018 Oct 1; 145(19): dev170019. Published online 2018 Oct 5. doi: 10.1242/dev.170019
PMCID:
PMC6514415
AbstractArticle
8.
The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo
Holly C. Williams, Jing Ma, Daiana Weiss, Bernard Lassègue, Roy Sutliff, Alejandra San Martín
Lab Invest. Author manuscript; available in PMC 2019 Apr 1.
Published in final edited form as: Lab Invest. 2019 Mar; 99(3): 399–410. Published online 2018 Oct 5. doi: 10.1038/s41374-018-0116-6
PMCID:
PMC6442944
AbstractArticlePDF–2.2M
9.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
10.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
11.
Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations
Ritsuko Morita, Miho Kihira, Yousuke Nakatsu, Yohei Nomoto, Miho Ogawa, Kazumasa Ohashi, Kensaku Mizuno, Tetsuhiko Tachikawa, Yukitaka Ishimoto, Yoshihiro Morishita, Takashi Tsuji
PLoS One. 2016; 11(9): e0161336. Published online 2016 Sep 2. doi: 10.1371/journal.pone.0161336
PMCID:
PMC5010284
AbstractArticlePDF–10M
12.
Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance
Kyle Caution, Mikhail A. Gavrilin, Mia Tazi, Apurva Kanneganti, Daniel Layman, Sheshadri Hoque, Kathrin Krause, Amal O. Amer
Sci Rep. 2015; 5: 18479. Published online 2015 Dec 21. doi: 10.1038/srep18479
PMCID:
PMC4685268
AbstractArticlePDF–1.9M
13.
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes
Robert Brommage, Jeff Liu, Gwenn M Hansen, Laura L Kirkpatrick, David G Potter, Arthur T Sands, Brian Zambrowicz, David R Powell, Peter Vogel
Bone Res. 2014; 2: 14034. Published online 2014 Oct 28. doi: 10.1038/boneres.2014.34
PMCID:
PMC4472125
AbstractArticlePDF–1.6M
14.
PLCε, PKD1, and SSH1L Transduce RhoA Signaling to Protect Mitochondria from Oxidative Stress in the Heart
Sunny Y. Xiang, Kunfu Ouyang, Bryan S. Yung, Shigeki Miyamoto, Alan V. Smrcka, Ju Chen, Joan Heller Brown
Sci Signal. Author manuscript; available in PMC 2014 Dec 17.
Published in final edited form as: Sci Signal. 2013 Dec 17; 6(306): ra108. Published online 2013 Dec 17. doi: 10.1126/scisignal.2004405
PMCID:
PMC4035240
AbstractArticlePDF–1.8M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
EphA Signaling Promotes Actin-based Dendritic Spine Remodeling through Slingshot Phosphatase
Lei Zhou, Emma V. Jones, Keith K. Murai
J Biol Chem. 2012 Mar 16; 287(12): 9346–9359. Published online 2012 Jan 26. doi: 10.1074/jbc.M111.302802
PMCID:
PMC3308827
AbstractArticlePDF–3.4M
17.
Platelet-derived Growth Factor (PDGF) Regulates Slingshot Phosphatase Activity via Nox1-dependent Auto-dephosphorylation of Serine 834 in Vascular Smooth Muscle Cells
Mithunan Maheswaranathan, Hope K. A. Gole, Isabel Fernandez, Bernard Lassègue, Kathy K. Griendling, Alejandra San Martín
J Biol Chem. 2011 Oct 14; 286(41): 35430–35437. Published online 2011 Aug 20. doi: 10.1074/jbc.M111.268284
Correction in:
J Biol Chem. 2020 Jun 12; 295(24): 8348.
PMCID:
PMC3195626
AbstractArticlePDF–1.0M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation
Timothy Y. Huang, Laurie S. Minamide, James R. Bamburg, Gary M. Bokoch
Dev Cell. Author manuscript; available in PMC 2009 Nov 1.
Published in final edited form as: Dev Cell. 2008 Nov; 15(5): 691–703. doi: 10.1016/j.devcel.2008.09.017
PMCID:
PMC2644054
AbstractArticlePDF–2.4M

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