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Items: 1 to 20 of 81

1.
Internalisation of neutrophils extracellular traps by macrophages aggravate rheumatoid arthritis via Rab5a
Haixin Ye, Qian Yang, Huaxia Guo, Xing Wang, Lifang Cheng, Bingqi Han, Mukeng Hong, Fopei Ma, Meng Li, Xianghui Wu, Feilong Chen, Junqing Zhu, Shixian Chen, Songyuan Zheng, Juan Li
RMD Open. 2024; 10(1): e003847. Published online 2024 Mar 14. doi: 10.1136/rmdopen-2023-003847
PMCID:
PMC10941157
AbstractArticlePDF–17M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
4.
PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination
Xinfang Yu, Wei Li, Haidan Liu, Xu Wang, Cristian Coarfa, Chao Cheng, Xinlian Yu, Zhaoyang Zeng, Ya Cao, Ken H. Young, Yong Li
J Clin Invest. 2023 Feb 1; 133(3): e160456. Published online 2023 Feb 1. doi: 10.1172/JCI160456
PMCID:
PMC9888393
AbstractArticlePDF–5.0M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Rab5a activates IRS1 to coordinate IGF-AKT-mTOR signaling and myoblast differentiation during muscle regeneration
Xiao Xia Cong, Xiu Kui Gao, Xi Sheng Rao, Jie Wen, Xiao Ceng Liu, Yin Pu Shi, Min Yi He, Wei Liang Shen, Yue Shen, Hongwei Ouyang, Ping Hu, Boon Chuan Low, Zhuo Xian Meng, Yue Hai Ke, Ming Zhu Zheng, Lin Rong Lu, Yong Heng Liang, Li Ling Zheng, Yi Ting Zhou
Cell Death Differ. 2020 Aug; 27(8): 2344–2362. Published online 2020 Feb 12. doi: 10.1038/s41418-020-0508-1
PMCID:
PMC7370222
AbstractArticlePDF–8.4M
7.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
8.
Rapsyn Escorts the Nicotinic Acetylcholine Receptor Along the Exocytic Pathway via Association with Lipid Rafts
Sophie Marchand, Anne Devillers-Thiéry, Stéphanie Pons, Jean-Pierre Changeux, Jean Cartaud
J Neurosci. 2002 Oct 15; 22(20): 8891–8901. doi: 10.1523/JNEUROSCI.22-20-08891.2002
PMCID:
PMC6757681
AbstractArticlePDF–1.0M
9.
Cardiomyocyte orientation modulated by the Numb family proteins–N-cadherin axis is essential for ventricular wall morphogenesis
Lianjie Miao, Jingjing Li, Jian Li, Yangyang Lu, David Shieh, Joseph E. Mazurkiewicz, Margarida Barroso, John J. Schwarz, Hong-Bo Xin, Harold A. Singer, Peter A. Vincent, Weimin Zhong, Glenn L. Radice, Leo Q. Wan, Zhen-Chuan Fan, Guoying Huang, Mingfu Wu
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15560–15569. Published online 2019 Jul 12. doi: 10.1073/pnas.1904684116
PMCID:
PMC6681736
AbstractArticlePDF–3.6M
10.
Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons
Gülçin Vardar, Shuwen Chang, Marife Arancillo, Yuan-Ju Wu, Thorsten Trimbuch, Christian Rosenmund
J Neurosci. 2016 Jul 27; 36(30): 7911–7924. doi: 10.1523/JNEUROSCI.1314-16.2016
PMCID:
PMC6601879
AbstractArticlePDF–3.9M
11.
ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration
Takuo Hirose, Alfredo Cabrera-Socorro, David Chitayat, Thomas Lemonnier, Olivier Féraud, Carmen Cifuentes-Diaz, Nicolas Gervasi, Cedric Mombereau, Tanay Ghosh, Loredana Stoica, Jeanne d’Arc Al Bacha, Hiroshi Yamada, Marcel A. Lauterbach, Marc Guillon, Kiriko Kaneko, Joy W. Norris, Komudi Siriwardena, Susan Blasér, Jérémie Teillon, Roberto Mendoza-Londono, Marion Russeau, Julien Hadoux, Sadayoshi Ito, Pierre Corvol, Maria G. Matheus, Kenton R. Holden, Kohji Takei, Valentina Emiliani, Annelise Bennaceur-Griscelli, Charles E. Schwartz, Genevieve Nguyen, Matthias Groszer
J Clin Invest. 2019 May 1; 129(5): 2145–2162. Published online 2019 Apr 15. doi: 10.1172/JCI79990
PMCID:
PMC6486358
AbstractArticlePDF–23M
12.
Retrograde transport of Akt by a neuronal Rab5-APPL1 endosome
Livia Goto-Silva, Marisa P. McShane, Sara Salinas, Yannis Kalaidzidis, Giampietro Schiavo, Marino Zerial
Sci Rep. 2019; 9: 2433. Published online 2019 Feb 21. doi: 10.1038/s41598-019-38637-0
PMCID:
PMC6385319
AbstractArticlePDF–4.3M
13.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
14.
RNA binding proteins co-localize with small tau inclusions in tauopathy
Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin
Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5
PMCID:
PMC6069705
AbstractArticlePDF–5.5M
15.
Ulk1 Governs Nerve Growth Factor/TrkA Signaling by Mediating Rab5 GTPase Activation in Porcine Hemagglutinating Encephalomyelitis Virus-Induced Neurodegenerative Disorders
Zi Li, Kui Zhao, Xiaoling Lv, Yungang Lan, Shiyu Hu, Junchao Shi, Jiyu Guan, Yawen Yang, Huijun Lu, Hongbin He, Feng Gao, Wenqi He
J Virol. 2018 Aug 15; 92(16): e00325-18. Prepublished online 2018 Jun 6. Published online 2018 Jul 31. doi: 10.1128/JVI.00325-18
PMCID:
PMC6069187
AbstractArticlePDF–4.5M
16.
The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart
Zakery N Baker, Kimberly Jett, Aren Boulet, Amzad Hossain, Paul A Cobine, Byung-Eun Kim, Amr M El Zawily, Ling Lee, Glen F Tibbits, Michael J Petris, Scot C Leary
Hum Mol Genet. 2017 Dec 1; 26(23): 4617–4628. Published online 2017 Sep 4. doi: 10.1093/hmg/ddx344
PMCID:
PMC5886179
AbstractArticlePDF–1.2M
17.
ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells
Jocelyn F. Krey, Rachel A. Dumont, Philip A. Wilmarth, Larry L. David, Kenneth R. Johnson, Peter G. Barr-Gillespie
J Neurosci. 2018 Jan 24; 38(4): 843–857. doi: 10.1523/JNEUROSCI.2658-17.2017
PMCID:
PMC5783965
AbstractArticlePDF–9.3M
18.
Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development
Wei Yang, Lisa Garrett, Di Feng, Gene Elliott, Xilin Liu, Ni Wang, Yu Ming Wong, Nga Ting Choi, Yingzi Yang, Bo Gao
Cell Res. 2017 Dec; 27(12): 1466–1484. Published online 2017 Oct 20. doi: 10.1038/cr.2017.127
PMCID:
PMC5717403
AbstractArticlePDF–12M
19.
Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice
Seung-Wook Shin, Edgar John Vogt, Maria Jimenez-Movilla, Boris Baibakov, Jurrien Dean
Nat Commun. 2017; 8: 1643. Published online 2017 Nov 21. doi: 10.1038/s41467-017-01387-6
PMCID:
PMC5696369
AbstractArticlePDF–5.1M
20.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program
John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt
PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682
PMCID:
PMC5503261
AbstractArticlePDF–31M

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