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Select item 110948821.

Dorsal root ganglion-derived exosomes deteriorate neuropathic pain by activating microglia via the microRNA-16-5p/HECTD1/HSP90 axis

Yinghao Xing, Pei Li, Yuanyuan Jia, Kexin Zhang, Ming Liu, Jingjing Jiang

Biol Res. 2024; 57: 28. Published online 2024 May 15. doi: 10.1186/s40659-024-00513-1

PMCID:: PMC11094882

Abstract Article PDF–4.6M

Select item 109193102.

miR-16-5p aggravates sepsis-associated acute kidney injury by inducing apoptosis

Han Li, Junyan Duan, Tongtong Zhang, Yingjie Fu, Yue Xu, Hongjun Miao, Xuhua Ge

Ren Fail. 2024; 46(1): 2322688. Published online 2024 Mar 6. doi: 10.1080/0886022X.2024.2322688

PMCID:: PMC10919310

Abstract Article PDF–7.9M

Select item 107743623.

miR-195b is required for proper cellular homeostasis in the elderly

Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco

Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8

PMCID:: PMC10774362

Abstract Article PDF–3.7M

Select item 106647504.

An essential role for miR-15/16 in Treg suppression and restriction of proliferation

Kristina Johansson, John D. Gagnon, Simon K. Zhou, Marlys S. Fassett, Andrew W. Schroeder, Robin Kageyama, Rodriel A. Bautista, Hewlett Pham, Prescott G. Woodruff, K. Mark Ansel

Cell Rep. Author manuscript; available in PMC 2023 Nov 22.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113298. Published online 2023 Oct 19. doi: 10.1016/j.celrep.2023.113298

PMCID:: PMC10664750

Abstract Article PDF–3.6M

Select item 101911325.

MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16

Seongkyun Lim, David E. Lee, Francielly Morena da Silva, Pieter J. Koopmans, Ivan J. Vechetti, Jr, Ferdinand von Walden, Nicholas P. Greene, Kevin A. Murach

Am J Physiol Cell Physiol. 2023 May 1; 324(5): C1101–C1109. Published online 2023 Mar 27. doi: 10.1152/ajpcell.00071.2023

PMCID:: PMC10191132

Abstract Article

Select item 96475336.

MicroRNA-16 inhibits the TLR4/NF-κB pathway and maintains tight junction integrity in irritable bowel syndrome with diarrhea

Meijuan Xi, Ping Zhao, Fang Li, Han Bao, Sijie Ding, Lijiang Ji, Jing Yan

J Biol Chem. 2022 Nov; 298(11): 102461. Published online 2022 Sep 5. doi: 10.1016/j.jbc.2022.102461

PMCID:: PMC9647533

Abstract Article PDF–4.9M

Select item 88970197.

Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner

Seongkyun Lim, J. William Deaver, Megan E. Rosa-Caldwell, David E. Lee, Francielly Morena da Silva, Ana Regina Cabrera, Eleanor R. Schrems, Landen W. Saling, Tyrone A. Washington, James D. Fluckey, Nicholas P. Greene

Am J Physiol Endocrinol Metab. 2022 Mar 1; 322(3): E278–E292. Published online 2022 Jan 24. doi: 10.1152/ajpendo.00333.2021

PMCID:: PMC8897019

Abstract Article

Select item 88611218.

T-cell activation decreases miRNA-15a/16 levels to promote MEK1–ERK1/2–Elk1 signaling and proliferative capacity

Frank Urena, Chi Ma, FuKun W. Hoffmann, Lance G.A. Nunes, Johann Urschitz, Stefan Moisyadi, Vedbar S. Khadka, Youping Deng, Peter R. Hoffmann

J Biol Chem. 2022 Mar; 298(3): 101634. Published online 2022 Jan 25. doi: 10.1016/j.jbc.2022.101634

PMCID:: PMC8861121

Abstract Article PDF–2.0M

Select item 85049519.

Genetic deletion of endothelial microRNA-15a/16-1 promotes cerebral angiogenesis and neurological recovery in ischemic stroke through Src signaling pathway

Ping Sun, Feifei Ma, Yang Xu, Chao Zhou, R. Anne Stetler, Ke-Jie Yin

J Cereb Blood Flow Metab. 2021 Oct; 41(10): 2725–2742. Published online 2021 Apr 28. doi: 10.1177/0271678X211010351

PMCID:: PMC8504951

Abstract Article PDF–3.1M

Select item 803345510.

miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms

Tomasz Sewastianik, Juerg R. Straubhaar, Jian-Jun Zhao, Mehmet K. Samur, Keith Adler, Helen E. Tanton, Vignesh Shanmugam, Omar Nadeem, Peter S. Dennis, Vinodh Pillai, Jianli Wang, Meng Jiang, Jianhong Lin, Ying Huang, Daniel Brooks, Mary Bouxsein, David M. Dorfman, Geraldine S. Pinkus, Davide F. Robbiani, Irene M. Ghobrial, Bogdan Budnik, Petr Jarolim, Nikhil C. Munshi, Kenneth C. Anderson, Ruben D. Carrasco

Blood. 2021 Apr 8; 137(14): 1905–1919. Prepublished online 2021 Jan 13. doi: 10.1182/blood.2020009088

PMCID:: PMC8033455

Abstract Article

Select item 798438411.

Differential roles of miR‐15a/16‐1 and miR‐497/195 clusters in immune cell development and homeostasis

Katharina Hutter, Thomas Rülicke, Mathias Drach, Lill Andersen, Andreas Villunger, Sebastian Herzog

FEBS J. 2021 Mar; 288(5): 1533–1545. Published online 2020 Aug 4. doi: 10.1111/febs.15493

PMCID:: PMC7984384

Abstract Article PDF–1.2M

Select item 748142912.

Induced pluripotent stem cells-derived microvesicles accelerate deep second-degree burn wound healing in mice through miR-16-5p-mediated promotion of keratinocytes migration

Yuan Yan, Ruijun Wu, Yunyao Bo, Min Zhang, Yinghua Chen, Xueer Wang, Mianbo Huang, Baiting Liu, Lin Zhang

Theranostics. 2020; 10(22): 9970–9983. Published online 2020 Aug 8. doi: 10.7150/thno.46639

PMCID:: PMC7481429

Abstract Article PDF–3.0M

Select item 717202013.

Endothelium-Targeted Deletion of microRNA-15a/16–1 Promotes Post-Stroke Angiogenesis and Improves Long-Term Neurological Recovery

Ping Sun, Kai Zhang, Sulaiman H. Hassan, Xuejing Zhang, Xuelian Tang, Hongjian Pu, R. Anne Stetler, Jun Chen, Ke-Jie Yin

Circ Res. Author manuscript; available in PMC 2021 Apr 10.

Published in final edited form as: Circ Res. 2020 Apr 10; 126(8): 1040–1057. Published online 2020 Mar 5. doi: 10.1161/CIRCRESAHA.119.315886

PMCID:: PMC7172020

Abstract Article PDF–4.3M

Select item 716013214.

XPO5 promotes primary miRNA processing independently of RanGTP

Jingjing Wang, Jerome E. Lee, Kent Riemondy, Yang Yu, Steven M. Marquez, Eric C. Lai, Rui Yi

Nat Commun. 2020; 11: 1845. Published online 2020 Apr 15. doi: 10.1038/s41467-020-15598-x

PMCID:: PMC7160132

Abstract Article PDF–5.0M

Select item 694410915.

miR‐15a‐5p, miR‐15b‐5p, and miR‐16‐5p inhibit tumor progression by directly targeting MYCN in neuroblastoma

Srinivas Chava, C. Patrick Reynolds, Anup S. Pathania, Santhi Gorantla, Larisa Y. Poluektova, Don W. Coulter, Subash C. Gupta, Manoj K. Pandey, Kishore B. Challagundla

Mol Oncol. 2020 Jan; 14(1): 180–196. Published online 2019 Nov 29. doi: 10.1002/1878-0261.12588

PMCID:: PMC6944109

Abstract Article PDF–2.2M

Select item 671515216.

miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival

John D. Gagnon, Robin Kageyama, Hesham M. Shehata, Marlys S. Fassett, Darryl J. Mar, Eric J. Wigton, Kristina Johansson, Adam J. Litterman, Pamela Odorizzi, Dimitre Simeonov, Brian J. Laidlaw, Marisella Panduro, Sana Patel, Lukas T. Jeker, Margaret E. Feeney, Michael T. McManus, Alexander Marson, Mehrdad Matloubian, Shomyseh Sanjabi, K. Mark Ansel

Cell Rep. Author manuscript; available in PMC 2019 Aug 29.

Published in final edited form as: Cell Rep. 2019 Aug 20; 28(8): 2169–2181.e4. doi: 10.1016/j.celrep.2019.07.064

PMCID:: PMC6715152

Abstract Article PDF–2.7M

Select item 655762117.

Regulation of gene expression by miR-144/451 during mouse erythropoiesis

Peng Xu, Lance E. Palmer, Christophe Lechauve, Guowei Zhao, Yu Yao, Jing Luan, Anastasios Vourekas, Haiyan Tan, Junmin Peng, John D. Schuetz, Zissimos Mourelatos, Gang Wu, Mitchell J. Weiss, Vikram R. Paralkar

Blood. 2019 Jun 6; 133(23): 2518–2528. Prepublished online 2019 Apr 10. doi: 10.1182/blood.2018854604

PMCID:: PMC6557621

Abstract Article

Select item 634917518.

MiR‐15a/16‐1 deficiency induces IL‐10‐producing CD19⁺ TIM‐1⁺ cells in tumor microenvironment

Xiaoqin Jia, Hao Liu, Chong Xu, Sen Han, Yating Shen, Xin Miao, Xiangyu Hu, Zhijie Lin, Li Qian, Zhengbing Wang, Weijuan Gong

J Cell Mol Med. 2019 Feb; 23(2): 1343–1353. Published online 2018 Nov 23. doi: 10.1111/jcmm.14037

PMCID:: PMC6349175

Abstract Article PDF–1.5M

Select item 630494319.

Knockout of both miR-15/16 loci induces acute myeloid leukemia

Francesca Lovat, Matteo Fassan, Diana Sacchi, Parvathi Ranganathan, Alexey Palamarchuk, Marius Bill, Malith Karunasiri, Pierluigi Gasparini, Giovanni Nigita, Rosario Distefano, Dario Veneziano, Adrienne M. Dorrance, Ramiro Garzon, Carlo M. Croce

Proc Natl Acad Sci U S A. 2018 Dec 18; 115(51): 13069–13074. Published online 2018 Nov 26. doi: 10.1073/pnas.1814980115

PMCID:: PMC6304943

Abstract Article PDF–2.2M

Select item 628769520.

Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism

Silvia Zecchini, Matteo Giovarelli, Cristiana Perrotta, Federica Morisi, Thierry Touvier, Ilaria Di Renzo, Claudia Moscheni, Maria Teresa Bassi, Davide Cervia, Marco Sandri, Emilio Clementi, Clara De Palma

Autophagy. 2019; 15(1): 58–77. Published online 2018 Sep 10. doi: 10.1080/15548627.2018.1507439

PMCID:: PMC6287695

Abstract Article PDF–4.3M

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