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Select item 83965501.

TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity

Sarah C. Atkinson, Steven M. Heaton, Michelle D. Audsley, Oded Kleifeld, Natalie A. Borg

Int J Mol Sci. 2021 Aug; 22(16): 9094. Published online 2021 Aug 23. doi: 10.3390/ijms22169094

PMCID:: PMC8396550

Abstract Article PDF–9.6M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79485703.

Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis

Georgi A. Georgiev, Mohammad Sharifian Gh., Jeff Romano, Karina L. Dias Teixeira, Craig Struble, Denise S. Ryan, Rose K. Sia, Jay P. Kitt, Joel M. Harris, Ku-Lung Hsu, Adam Libby, Marc G. Odrich, Tatiana Suárez, Robert L. McKown, Gordon W. Laurie

J Biol Chem. 2021 Jan-Jun; 296: 100070. Published online 2020 Nov 21. doi: 10.1074/jbc.RA120.015833

PMCID:: PMC7948570

Abstract Article PDF–3.2M

Select item 74273274.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 73985725.

The Lacritin-Syndecan-1-Heparanase Axis in Dry Eye Disease

Karina Dias-Teixeira, Xavier Horton, Robert McKown, Jeffrey Romano, Gordon W. Laurie

Adv Exp Med Biol. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Adv Exp Med Biol. 2020; 1221: 747–757. doi: 10.1007/978-3-030-34521-1_31

PMCID:: PMC7398572

Article PDF–430K

Select item 67781376.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 64240987.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

Select item 58391588.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

Select item 57375559.

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality

Helen Hoffmeister, Andreas Fuchs, Fabian Erdel, Sophia Pinz, Regina Gröbner-Ferreira, Astrid Bruckmann, Rainer Deutzmann, Uwe Schwartz, Rodrigo Maldonado, Claudia Huber, Anne-Sarah Dendorfer, Karsten Rippe, Gernot Längst

Nucleic Acids Res. 2017 Oct 13; 45(18): 10534–10554. Published online 2017 Aug 28. doi: 10.1093/nar/gkx711

PMCID:: PMC5737555

Abstract Article PDF–7.2M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 539515411.

Establishment of a tear protein biomarker panel differentiating between Graves’ disease with or without orbitopathy

Cecilie Aass, Ingrid Norheim, Erik Fink Eriksen, Ellen Charlotte Børnick, Per Medbøe Thorsby, Milaim Pepaj

PLoS One. 2017; 12(4): e0175274. Published online 2017 Apr 18. doi: 10.1371/journal.pone.0175274

PMCID:: PMC5395154

Abstract Article PDF–1005K

Select item 501331512.

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family

Xu Li, Kim My Tran, Kathryn E. Aziz, Alexey V. Sorokin, Junjie Chen, Wenqi Wang

Mol Cell Proteomics. 2016 Sep; 15(9): 3030–3044. Published online 2016 Jul 18. doi: 10.1074/mcp.M116.060277

PMCID:: PMC5013315

Abstract Article PDF–3.2M

Select item 468093513.

Lacritin Salvages Human Corneal Epithelial Cells from Lipopolysaccharide Induced Cell Death

Venkat Rao Vantaku, Geetika Gupta, Krishna Chaitanya Rapalli, Roy Karnati

Sci Rep. 2015; 5: 18362. Published online 2015 Dec 16. doi: 10.1038/srep18362

PMCID:: PMC4680935

Abstract Article PDF–755K

Select item 464794114.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 461770115.

The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking

Ruxandra Bachmann-Gagescu, Margo Dona, Lisette Hetterschijt, Edith Tonnaer, Theo Peters, Erik de Vrieze, Dorus A. Mans, Sylvia E. C. van Beersum, Ian G. Phelps, Heleen H. Arts, Jan E. Keunen, Marius Ueffing, Ronald Roepman, Karsten Boldt, Dan Doherty, Cecilia B. Moens, Stephan C. F. Neuhauss, Hannie Kremer, Erwin van Wijk

PLoS Genet. 2015 Oct; 11(10): e1005575. Published online 2015 Oct 20. doi: 10.1371/journal.pgen.1005575

PMCID:: PMC4617701

Abstract Article PDF–13M

Select item 461721116.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 445609517.

A thermo-responsive protein treatment for dry eyes

Wan Wang, Aarti Jashnani, Suhaas R. Aluri, Joshua A. Gustafson, Pang-Yu Hsueh, Frances Yarber, Robert L. McKown, Gordon W. Laurie, Sarah F. Hamm-Alvarez, J. Andrew MacKay

J Control Release. Author manuscript; available in PMC 2016 Feb 10.

Published in final edited form as: J Control Release. 2015 Feb 10; 199: 156–167. Published online 2014 Dec 3. doi: 10.1016/j.jconrel.2014.11.016

PMCID:: PMC4456095

Abstract Article PDF–3.7M

Select item 427010418.

Lacritin-mediated regeneration of the corneal epithelia by protein polymer nanoparticles

Wan Wang, Jordan Despanie, Pu Shi, Maria C. Edman-Woolcott, Yi-An Lin, Honggang Cui, J. Martin Heur, M. Elizabeth Fini, Sarah F. Hamm-Alvarez, J. Andrew MacKay

J Mater Chem B Mater Biol Med. Author manuscript; available in PMC 2015 Dec 14.

Published in final edited form as: J Mater Chem B Mater Biol Med. 2014 Dec 14; 2(46): 8131–8141. doi: 10.1039/C4TB00979G

PMCID:: PMC4270104

Abstract Article PDF–1.6M

Select item 414892419.

Topical Administration of Lacritin Is a Novel Therapy for Aqueous-Deficient Dry Eye Disease

Trinka Vijmasi, Feeling Y. T. Chen, Suganthalakshmi Balasubbu, Marianne Gallup, Robert L. McKown, Gordon W. Laurie, Nancy A. McNamara

Invest Ophthalmol Vis Sci. 2014 Aug; 55(8): 5401–5409. Published online 2014 Aug 28. doi: 10.1167/iovs.14-13924

PMCID:: PMC4148924

Abstract Article PDF–611K

Select item 413923020.

A Cleavage-potentiated Fragment of Tear Lacritin Is Bactericidal

Robert L. McKown, Erin V. Coleman Frazier, Kaneil K. Zadrozny, Andrea M. Deleault, Ronald W. Raab, Denise S. Ryan, Rose K. Sia, Jae K. Lee, Gordon W. Laurie

J Biol Chem. 2014 Aug 8; 289(32): 22172–22182. Published online 2014 Jun 18. doi: 10.1074/jbc.M114.570143

PMCID:: PMC4139230

Abstract Article PDF–2.2M

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