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Select item 110822511.

CLK2 mediates IκBα-independent early termination of NF-κB activation by inducing cytoplasmic redistribution and degradation

Shang-Ze Li, Qi-Peng Shu, Hai-Meng Zhou, Yu-Ying Liu, Meng-Qi Fan, Xin-Yi Liang, Lin-Zhi Qi, Ya-Nan He, Xue-Yi Liu, Xue-Hua Du, Xi-Chen Huang, Yu-Zhen Chen, Run-Lei Du, Yue-Xiu Liang, Xiao-Dong Zhang

Nat Commun. 2024; 15: 3901. Published online 2024 May 9. doi: 10.1038/s41467-024-48288-z

PMCID:: PMC11082251

Abstract Article PDF–6.5M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104495793.

CLK2 in GABAergic neurons is critical in regulating energy balance and anxiety-like behavior in a gender-specific fashion

Sónia Norberto, Heloisa Balan Assalin, Dioze Guadagnini, Natália Tobar, Patrícia Aline Boer, Min-Cheol Kang, Mario Jose Abdalla Saad, Young-Bum Kim, Patricia Oliveira Prada

Front Endocrinol (Lausanne) 2023; 14: 1172835. Published online 2023 Aug 10. doi: 10.3389/fendo.2023.1172835

PMCID:: PMC10449579

Abstract Article PDF–5.1M

Select item 63334604.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 52990495.

Adipose tissue CLK2 promotes energy expenditure during high fat diet intermittent fasting

Maximilian Hatting, Amy K. Rines, Chi Luo, Mitsuhisa Tabata, Kfir Sharabi, Jessica A. Hall, Francisco Verdeguer, Christian Trautwein, Pere Puigserver

Cell Metab. Author manuscript; available in PMC 2018 Feb 7.

Published in final edited form as: Cell Metab. 2017 Feb 7; 25(2): 428–437. Published online 2017 Jan 12. doi: 10.1016/j.cmet.2016.12.007

PMCID:: PMC5299049

Abstract Article PDF–875K

Select item 39949606.

Cdc2-Like Kinase 2 Suppresses Hepatic Fatty Acid Oxidation and Ketogenesis Through Disruption of the PGC-1α and MED1 Complex

Mitsuhisa Tabata, Joseph T. Rodgers, Jessica A. Hall, Yoonjin Lee, Mark P. Jedrychowski, Steven P. Gygi, Pere Puigserver

Diabetes. 2014 May; 63(5): 1519–1532. Published online 2014 Apr 12. doi: 10.2337/db13-1304

PMCID:: PMC3994960

Abstract Article PDF–2.2M

Select item 35724107.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 31877058.

Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor

Kensuke Ninomiya, Naoyuki Kataoka, Masatoshi Hagiwara

J Cell Biol. 2011 Oct 3; 195(1): 27–40. doi: 10.1083/jcb.201107093

PMCID:: PMC3187705

Abstract Article PDF–3.0M

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 306066010.

Clk2 and B56β mediate insulin regulated assembly of the PP2A phosphatase holoenzyme complex on Akt

Joseph T. Rodgers, Rutger Vogel, Pere Puigserver

Mol Cell. Author manuscript; available in PMC 2012 Feb 18.

Published in final edited form as: Mol Cell. 2011 Feb 18; 41(4): 471–479. doi: 10.1016/j.molcel.2011.02.007

PMCID:: PMC3060660

Abstract Article PDF–1.1M

Select item 302253411.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 280762012.

Cdc2-like Kinase 2 is an Insulin Regulated Suppressor of Hepatic Gluconeogenesis

Joseph T. Rodgers, Wilhelm Haas, Steven P. Gygi, Pere Puigserver.

Cell Metab. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Cell Metab. 2010 Jan; 11(1): 23–34. doi: 10.1016/j.cmet.2009.11.006

PMCID:: PMC2807620

Abstract Article PDF–1.4M

Select item 255627013.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 237590814.

Detailed characterization of the mouse embryonic stem cell transcriptome reveals novel genes and intergenic splicing associated with pluripotency

Galih Kunarso, Kee-Yew Wong, Lawrence W Stanton, Leonard Lipovich

BMC Genomics. 2008; 9: 155. Published online 2008 Apr 9. doi: 10.1186/1471-2164-9-155

PMCID:: PMC2375908

Abstract Article PDF–933K

Select item 124228215.

Diversification of stem cell molecular repertoire by alternative splicing

Moshe Pritsker, Tirza T. Doniger, Laurie C. Kramer, Stephanie E. Westcot, Ihor R. Lemischka

Proc Natl Acad Sci U S A. 2005 Oct 4; 102(40): 14290–14295. Published online 2005 Sep 23. doi: 10.1073/pnas.0502132102

PMCID:: PMC1242282

Abstract Article PDF–664K

Select item 121872316.

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.

O Nayler, S Stamm, A Ullrich

Biochem J. 1997 Sep 15; 326(Pt 3): 693–700. doi: 10.1042/bj3260693

PMCID:: PMC1218723

Summary PDF–582K

Select item 43978317.

Genomic Analysis of Mouse Retinal Development

Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko

PLoS Biol. 2004 Sep; 2(9): e247. Published online 2004 Jun 29. doi: 10.1371/journal.pbio.0020247

PMCID:: PMC439783

Abstract Article PDF–975K

Select item 31099218.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

Select item 31098019.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Abstract Article PDF–1.4M

Select item 28355420.

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100

Correction in:: Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.

PMCID:: PMC283554

Abstract Article PDF–481K

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