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Select item 116586831.

Gonadal sex reversal at single-cell resolution in Znrf3-deficient mice

Raissa G. G. Kay, Richard Reeves, Pam Siggers, Simon Greenaway, Ann-Marie Mallon, Sara Wells, Bon-Kyoung Koo, Chloé Mayère, Serge Nef, Andy Greenfield, Michelle M. Simon

Development. 2024 Dec 1; 151(23): dev202707. Published online 2024 Dec 4. doi: 10.1242/dev.202707

PMCID:: PMC11658683

Article

Select item 114030592.

Follistatin controls the number of murine teeth by limiting TGF-β signaling

Shicheng Zhu, Suman Huo, Zhongzheng Wang, Caiyan Huang, Chuanxu Li, Hanjing Song, Xueqin Yang, Rui He, Cheng Ding, Mengsheng Qiu, Xiao-Jing Zhu

iScience. 2024 Sep 20; 27(9): 110785. Published online 2024 Aug 22. doi: 10.1016/j.isci.2024.110785

PMCID:: PMC11403059

Article PDF–5.0M

Select item 107535873.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Article

Select item 104740304.

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy

Hyun-Jun Jang, Yo Han Lee, Tam Dao, Yunju Jo, Keon Woo Khim, Hye-jin Eom, Ju Eun Lee, Yi Jin Song, Sun Sil Choi, Kieun Park, Haneul Ji, Young Chan Chae, Kyungjae Myung, Hongtae Kim, Dongryeol Ryu, Neung Hwa Park, Sung Ho Park, Jang Hyun Choi

Exp Mol Med. 2023 Aug; 55(8): 1720–1733. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01047-4

PMCID:: PMC10474030

Article PDF–5.1M

Select item 104107175.

Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve

Camilla H. K. Hughes, Olivia E. Smith, Marie-Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy

Proc Natl Acad Sci U S A. 2023 Aug 8; 120(32): e2220849120. Published online 2023 Jul 26. doi: 10.1073/pnas.2220849120

PMCID:: PMC10410717

Article PDF–3.9M

Select item 103904926.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Article PDF–13M

Select item 103078527.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Article PDF–8.8M

Select item 102199828.

Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2

Matthew J. Thompson, Caryl A. Young, Vidhya Munnamalai, David M. Umulis

Sci Rep. 2023; 13: 8567. Published online 2023 May 26. doi: 10.1038/s41598-023-34725-4

PMCID:: PMC10219982

Article PDF–3.1M

Select item 100337419.

Hepatic follistatin increases basal metabolic rate and attenuates diet-induced obesity during hepatic insulin resistance

Rongya Tao, Oliver Stöhr, Caixia Wang, Wei Qiu, Kyle D. Copps, Morris F. White

Mol Metab. 2023 May; 71: 101703. Published online 2023 Mar 10. doi: 10.1016/j.molmet.2023.101703

PMCID:: PMC10033741

Article PDF–3.6M

Select item 991045810.

Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals

Hei Yeun Koo, Min-A Kim, Hyehyun Min, Jae Yeon Hwang, Meenakshi Prajapati-DiNubila, Kwan Soo Kim, Martin M. Matzuk, Juw Won Park, Angelika Doetzlhofer, Un-Kyung Kim, Jinwoong Bok

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2213099120. Published online 2022 Dec 28. doi: 10.1073/pnas.2213099120

PMCID:: PMC9910458

Article PDF–11M

Select item 984574511.

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development

Laura Simonson, Ethan Oldham, Hao Chang

Development. 2022 Nov 15; 149(22): dev200816. Published online 2022 Nov 16. doi: 10.1242/dev.200816

PMCID:: PMC9845745

Article

Select item 974104412.

Follistatin Is a Novel Chemoattractant for Migration and Invasion of Placental Trophoblasts of Mice

Jing Li, Yan Qi, Ke Yang, Linjing Zhu, Xueling Cui, Zhonghui Liu

Cells. 2022 Dec; 11(23): 3816. Published online 2022 Nov 29. doi: 10.3390/cells11233816

PMCID:: PMC9741044

Article PDF–3.2M

Select item 967889713.

Depletion of CD206⁺ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration

Allah Nawaz, Muhammad Bilal, Shiho Fujisaka, Tomonobu Kado, Muhammad Rahil Aslam, Saeed Ahmed, Keisuke Okabe, Yoshiko Igarashi, Yoshiyuki Watanabe, Takahide Kuwano, Koichi Tsuneyama, Ayumi Nishimura, Yasuhiro Nishida, Seiji Yamamoto, Masakiyo Sasahara, Johji Imura, Hisashi Mori, Martin M. Matzuk, Fujimi Kudo, Ichiro Manabe, Akiyoshi Uezumi, Takashi Nakagawa, Yumiko Oishi, Kazuyuki Tobe

Nat Commun. 2022; 13: 7058. Published online 2022 Nov 21. doi: 10.1038/s41467-022-34191-y

PMCID:: PMC9678897

Article PDF–2.7M

Select item 948197514.

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu

Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539

PMCID:: PMC9481975

Article

Select item 938150415.

Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis

Junjun Jing, Jifan Feng, Yuan Yuan, Tingwei Guo, Jie Lei, Fei Pei, Thach-Vu Ho, Yang Chai

Nat Commun. 2022; 13: 4803. Published online 2022 Aug 16. doi: 10.1038/s41467-022-32490-y

PMCID:: PMC9381504

Article PDF–6.6M

Select item 920030716.

Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice

Alejo Torres-Cano, Rosa Portella-Fortuny, Claudia Müller-Sánchez, Sonia Porras-Marfil, Marina Ramiro-Pareta, You-Ying Chau, Manuel Reina, Francesc X. Soriano, Ofelia M. Martínez-Estrada

PLoS Genet. 2022 Jun; 18(6): e1010240. Published online 2022 Jun 15. doi: 10.1371/journal.pgen.1010240