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Items: 1 to 20 of 252

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
NOD2 attenuates osteoarthritis via reprogramming the activation of synovial macrophages
Changchuan Li, Zhuji Ouyang, Yuhsi Huang, Sipeng Lin, Shixun Li, Jing Xu, Taihe Liu, Jionglin Wu, Peidong Guo, Zhong Chen, Haoyu Wu, Yue Ding
Arthritis Res Ther. 2023; 25: 249. Published online 2023 Dec 20. doi: 10.1186/s13075-023-03230-4
Correction in:
Arthritis Res Ther. 2024; 26: 22.
PMCID:
PMC10731717
AbstractArticlePDF–2.3M
3.
Loss of NOD2 in macrophages improves colitis and tumorigenesis in a lysozyme-dependent manner
Camille Chauvin, Katarina Radulovic, Olivier Boulard, Myriam Delacre, Nadine Waldschmitt, Paul Régnier, Gauthier Legris, Clément Bouchez, Mohamed-Yassine Sleimi, Philip Rosenstiel, Guillaume Darrasse-Jèze, Mathias Chamaillard, Lionel F. Poulin
Front Immunol. 2023; 14: 1252979. Published online 2023 Oct 9. doi: 10.3389/fimmu.2023.1252979
PMCID:
PMC10590911
AbstractArticlePDF–7.0M
4.
Activation of Nod2 signaling upon norovirus infection enhances antiviral immunity and susceptibility to colitis
Ghaffar Muharram, Marion Thépaut, Pierre-Emmanuel Lobert, Teddy Grandjean, Olivier Boulard, Myriam Delacre, Emmrich Wakeford, Richard Wheeler, Lionel Franz Poulin, Ivo Gomperts Boneca, Frank Lafont, Marie-Cécile Michallet, Didier Hober, Ken Cadwell, Mathias Chamaillard
Gut Microbes. 2023; 15(2): 2249960. Published online 2023 Sep 1. doi: 10.1080/19490976.2023.2249960
PMCID:
PMC10478738
AbstractArticlePDF–3.4M
5.
NOD2 in monocytes negatively regulates macrophage development through TNFalpha
Camille Chauvin, Daniel Alvarez-Simon, Katarina Radulovic, Olivier Boulard, William Laine, Myriam Delacre, Nadine Waldschmitt, Elodie Segura, Jérome Kluza, Mathias Chamaillard, Lionel F. Poulin
Front Immunol. 2023; 14: 1181823. Published online 2023 Jun 21. doi: 10.3389/fimmu.2023.1181823
PMCID:
PMC10320732
AbstractArticlePDF–4.3M
6.
A probiotic bi-functional peptidoglycan hydrolase sheds NOD2 ligands to regulate gut homeostasis in female mice
Jie Gao, Lei Wang, Jing Jiang, Qian Xu, Nianyi Zeng, Bingyun Lu, Peibo Yuan, Kai Sun, Hongwei Zhou, Xiaolong He
Nat Commun. 2023; 14: 3338. Published online 2023 Jun 7. doi: 10.1038/s41467-023-38950-3
PMCID:
PMC10247697
AbstractArticlePDF–3.4M
7.
Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity
Ravi Bharadwaj, Christina F. Lusi, Siavash Mashayekh, Abhinit Nagar, Okuda, Amanda Monahan, Donggi Paik, Anubhab Nandy, Madison V. Anonick, William E. Goldman, Thirumala-Devi Kanneganti, Megan H. Orzalli, Catherine Leimkuhler Grimes, Prabhani U. Atukorale, Neal Silverman
Immunity. Author manuscript; available in PMC 2024 May 9.
Published in final edited form as: Immunity. 2023 May 9; 56(5): 998–1012.e8. Published online 2023 Apr 27. doi: 10.1016/j.immuni.2023.04.001
PMCID:
PMC10195032
AbstractArticlePDF–2.5M
8.
Autophagy controls mucus secretion from intestinal goblet cells by alleviating ER stress
Maria Naama, Shahar Telpaz, Aya Awad, Shira Ben-Simon, Sarina Harshuk-Shabso, Sonia Modilevsky, Elad Rubin, Jasmin Sawaed, Lilach Zelik, Mor Zigdon, Nofar Asulin, Sondra Turjeman, Michal Werbner, Supapit Wongkuna, Rachel Feeney, Bjoern O. Schroeder, Abraham Nyska, Meital Nuriel-Ohayon, Shai Bel
Cell Host Microbe. 2023 Mar 8; 31(3): 433–446.e4. doi: 10.1016/j.chom.2023.01.006
PMCID:
PMC10016318
AbstractArticle
9.
The crosstalk between microbial sensors ELMO1 and NOD2 shape intestinal immune responses
Aditi Sharma, Sajan Chandrangadhan Achi, Stella-Rita Ibeawuchi, Mahitha Shree Anandachar, Hobie Gementera, Uddeep Chaudhury, Fatima Usmani, Kevin Vega, Ibrahim M Sayed, Soumita Das
Virulence. 2023; 14(1): 2171690. Published online 2023 Feb 19. doi: 10.1080/21505594.2023.2171690
PMCID:
PMC9980453
AbstractArticlePDF–2.4M
10.
NOD2 inhibits the proliferation of esophageal adenocarcinoma cells through autophagy
Xiaozhi Li, Suo Liu, Longyu Jin, Yuchao Ma, Tao Liu
J Cancer Res Clin Oncol. 2023; 149(2): 639–652. Published online 2022 Oct 31. doi: 10.1007/s00432-022-04354-x
PMCID:
PMC9931811
AbstractArticlePDF–4.4M
11.
Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function
Liming Mao, Atika Dhar, Guangxun Meng, Ivan Fuss, Kim Montgomery-Recht, Zhiqiong Yang, Qiuyun Xu, Atsushi Kitani, Warren Strober
Front Immunol. 2022; 13: 988862. Published online 2022 Sep 15. doi: 10.3389/fimmu.2022.988862
PMCID:
PMC9520668
AbstractArticlePDF–15M
12.
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation
Che A. Stafford, Alicia-Marie Gassauer, Carina C. de Oliveira Mann, Maria C. Tanzer, Evelyn Fessler, Benedikt Wefers, Dennis Nagl, Gunnar Kuut, Karolina Sulek, Catherine Vasilopoulou, Sophia J. Schwojer, Andreas Wiest, Marie K. Pfautsch, Wolfgang Wurst, Monica Yabal, Thomas Fröhlich, Matthias Mann, Nicolas Gisch, Lucas T. Jae, Veit Hornung
Nature. 2022; 609(7927): 590–596. Published online 2022 Aug 24. doi: 10.1038/s41586-022-05125-x
PMCID:
PMC9477735
AbstractArticlePDF–10M
13.
Mice Dually Disrupted for Nod2 and Mincle Manifest Early Bacteriological Control but Late Susceptibility During Mycobacterium tuberculosis Infection
Jean-Yves Dubé, Fiona McIntosh, Marcel A. Behr
Front Immunol. 2022; 13: 862992. Published online 2022 Mar 28. doi: 10.3389/fimmu.2022.862992
PMCID:
PMC8995500
AbstractArticlePDF–5.0M
14.
The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota
Stephen J. Blake, Jane James, Feargal J. Ryan, Jose Caparros-Martin, Georgina L. Eden, Yee C. Tee, John R. Salamon, Saoirse C. Benson, Damon J. Tumes, Anastasia Sribnaia, Natalie E. Stevens, John W. Finnie, Hiroki Kobayashi, Deborah L. White, Steve L. Wesselingh, Fergal O’Gara, Miriam A. Lynn, David J. Lynn
Cell Rep Med. 2021 Dec 21; 2(12): 100464. Published online 2021 Dec 8. doi: 10.1016/j.xcrm.2021.100464
PMCID:
PMC8714857
AbstractArticlePDF–5.9M
15.
Attenuation of apoptotic cell detection triggers thymic regeneration after damage
Sinéad Kinsella, Cindy A. Evandy, Kirsten Cooper, Lorenzo Iovino, Paul C. deRoos, Kayla S. Hopwo, David W. Granadier, Colton W. Smith, Shahin Rafii, Jarrod A. Dudakov
Cell Rep. Author manuscript; available in PMC 2021 Nov 28.
Published in final edited form as: Cell Rep. 2021 Oct 5; 37(1): 109789. doi: 10.1016/j.celrep.2021.109789
PMCID:
PMC8627669
AbstractArticlePDF–2.0M
16.
Ileocolonic Healing After Extended Small Bowel Resection in Mice: NOD2 Deficiency Impairs Anastomotic Healing and Postoperative Outcome
Maria Witte, Johannes Reiner, Karen Bannert, Robert Jaster, Christian Maschmeier, Clemens Schafmayer, Georg Lamprecht, Peggy Berlin
Inflamm Bowel Dis. 2021 Sep; 27(9): 1503–1512. Published online 2021 Feb 8. doi: 10.1093/ibd/izab022
PMCID:
PMC8376130
AbstractArticlePDF–11M
17.
Nucleotide-binding oligomerization domain-containing protein 2 (Nod2) modulates T1DM susceptibility by gut microbiota
Yang-yang Li, James A. Pearson, Chen Chao, Jian Peng, Xiaojun Zhang, Zhiguang Zhou, Yu Liu, F. Susan Wong, Li Wen
J Autoimmun. Author manuscript; available in PMC 2021 Jul 16.
Published in final edited form as: J Autoimmun. 2017 Aug; 82: 85–95. Published online 2017 Jun 4. doi: 10.1016/j.jaut.2017.05.007
PMCID:
PMC8284907
AbstractArticlePDF–2.9M
18.
Neonatal exposure to commensal bacteria-derived antigens directs polysaccharide-specific B-1 B cell repertoire development
J. Stewart New, Brian L.P. Dizon, Christopher Fucile, Alexander F. Rosenberg, John F. Kearney, R. Glenn King
Immunity. Author manuscript; available in PMC 2021 Jul 14.
Published in final edited form as: Immunity. 2020 Jul 14; 53(1): 172–186.e6. Published online 2020 Jun 30. doi: 10.1016/j.immuni.2020.06.006
PMCID:
PMC7971260
AbstractArticlePDF–2.5M
19.
Blue Light Induces Impaired Autophagy through Nucleotide-Binding Oligomerization Domain 2 Activation on the Mouse Ocular Surface
Ying Li, Rujun Jin, Lan Li, Ji Suk Choi, Jonghwa Kim, Hyeon Jeong Yoon, Jong Hwan Park, Kyung Chul Yoon
Int J Mol Sci. 2021 Feb; 22(4): 2015. Published online 2021 Feb 18. doi: 10.3390/ijms22042015
PMCID:
PMC7922400
AbstractArticlePDF–2.1M
20.
NOD2 drives early IL-33–dependent expansion of group 2 innate lymphoid cells during Crohn’s disease–like ileitis
Carlo De Salvo, Kristine-Ann Buela, Brecht Creyns, Daniele Corridoni, Nitish Rana, Hannah L. Wargo, Chiara L. Cominelli, Peter G. Delaney, Alexander Rodriguez-Palacios, Fabio Cominelli, Séverine Vermeire, Theresa T. Pizarro
J Clin Invest. 2021 Mar 1; 131(5): e140624. Published online 2021 Mar 1. doi: 10.1172/JCI140624
PMCID:
PMC7919719
AbstractArticlePDF–4.3M

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