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Items: 1 to 20 of 42

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
KCNQ2/3 Gain-of-Function Variants and Cell Excitability: Differential Effects in CA1 versus L2/3 Pyramidal Neurons
Nissi Varghese, Bruno Moscoso, Ana Chavez, Kristen Springer, Erika Ortiz, Heun Soh, Sabato Santaniello, Atul Maheshwari, Anastasios V. Tzingounis
J Neurosci. 2023 Sep 20; 43(38): 6479–6494. doi: 10.1523/JNEUROSCI.0980-23.2023
PMCID:
PMC10513074
AbstractArticlePDF–4.5M
4.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
5.
Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
Hyoseon Oh, Suho Lee, Yusang Oh, Seongbin Kim, Young Seo Kim, Yeji Yang, Woochul Choi, Ye-Eun Yoo, Heejin Cho, Seungjoon Lee, Esther Yang, Wuhyun Koh, Woojin Won, Ryunhee Kim, C. Justin Lee, Hyun Kim, Hyojin Kang, Jin Young Kim, Taeyun Ku, Se-Bum Paik, Eunjoon Kim
Nat Commun. 2023; 14: 3547. Published online 2023 Jun 15. doi: 10.1038/s41467-023-39203-z
PMCID:
PMC10272139
AbstractArticlePDF–4.3M
6.
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex
Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Ziv Porat, Ingrid E. Scheffer, David B. Goldstein, Orrin Devinsky, Orly Reiner
Nat Commun. 2022; 13: 4209. Published online 2022 Jul 21. doi: 10.1038/s41467-022-31752-z
PMCID:
PMC9304408
AbstractArticlePDF–13M
7.
Autism-associated mutations in KV7 channels induce gating pore current
Tamer M. Gamal El-Din, Timothy Lantin, Christopher W. Tschumi, Barbara Juarez, Meagan Quinlan, Julia H. Hayano, Jin Li, Larry S. Zweifel, William A. Catterall
Proc Natl Acad Sci U S A. 2021 Nov 9; 118(45): e2112666118. Published online 2021 Nov 2. doi: 10.1073/pnas.2112666118
PMCID:
PMC8609342
AbstractArticlePDF–1.3M
8.
The SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channels
Xu Chen, Yuhong Zhang, Xiang Ren, Qi Su, Yan Liu, Xing Dang, Yuanyuan Qin, Xinyi Yang, Zhengcao Xing, Yajie Shen, Yaya Wang, Zhantao Bai, Edward T.H. Yeh, Hongmei Wu, Yitao Qi
J Biol Chem. 2021 Oct; 297(4): 101183. Published online 2021 Sep 10. doi: 10.1016/j.jbc.2021.101183
PMCID:
PMC8488601
AbstractArticlePDF–3.7M
9.
Place fields of single spikes in hippocampus involve Kcnq3 channel-dependent entrainment of complex spike bursts
Xiaojie Gao, Franziska Bender, Heun Soh, Changwan Chen, Mahsa Altafi, Sebastian Schütze, Matthias Heidenreich, Maria Gorbati, Mihaela-Anca Corbu, Marta Carus-Cadavieco, Tatiana Korotkova, Anastasios V. Tzingounis, Thomas J. Jentsch, Alexey Ponomarenko
Nat Commun. 2021; 12: 4801. Published online 2021 Aug 10. doi: 10.1038/s41467-021-24805-2
PMCID:
PMC8355348
AbstractArticlePDF–2.2M
10.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
11.
CRISPR knockdown of Kcnq3 attenuates the M-current and increases excitability of NPY/AgRP neurons to alter energy balance
Todd L. Stincic, Martha A. Bosch, Avery C. Hunker, Barbara Juarez, Ashley M. Connors, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly
Mol Metab. 2021 Jul; 49: 101218. Published online 2021 Mar 22. doi: 10.1016/j.molmet.2021.101218
PMCID:
PMC8093934
AbstractArticlePDF–2.7M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
A Chromatin Accessibility Atlas of the Developing Human Telencephalon
Eirene Markenscoff-Papadimitriou, Sean Whalen, Pawel Przytycki, Reuben Thomas, Fadya Binyameen, Tomasz J. Nowakowski, Arnold R. Kriegstein, Stephan J. Sanders, Matthew W. State, Katherine S. Pollard, John L. Rubenstein
Cell. Author manuscript; available in PMC 2021 Aug 6.
Published in final edited form as: Cell. 2020 Aug 6; 182(3): 754–769.e18. Published online 2020 Jun 30. doi: 10.1016/j.cell.2020.06.002
PMCID:
PMC7415678
AbstractArticlePDF–2.2M
14.
KCNQ2 Is a Nodal K+ Channel
Jérôme J. Devaux, Kleopas A. Kleopa, Edward C. Cooper, Steven S. Scherer
J Neurosci. 2004 Feb 4; 24(5): 1236–1244. doi: 10.1523/JNEUROSCI.4512-03.2004
PMCID:
PMC6793582
AbstractArticlePDF–1.0M
15.
Calmodulin Is an Auxiliary Subunit of KCNQ2/3 Potassium Channels
Hua Wen, Irwin B. Levitan
J Neurosci. 2002 Sep 15; 22(18): 7991–8001. doi: 10.1523/JNEUROSCI.22-18-07991.2002
PMCID:
PMC6758071
AbstractArticlePDF–429K
16.
A Common Ankyrin-G-Based Mechanism Retains KCNQ and NaV Channels at Electrically Active Domains of the Axon
Zongming Pan, Tingching Kao, Zsolt Horvath, Julia Lemos, Jai-Yoon Sul, Stephen D. Cranstoun, Vann Bennett, Steven S. Scherer, Edward C. Cooper
J Neurosci. 2006 Mar 8; 26(10): 2599–2613. doi: 10.1523/JNEUROSCI.4314-05.2006
PMCID:
PMC6675151
AbstractArticlePDF–2.4M
17.
The Neonatal Ventromedial Hypothalamus Transcriptome Reveals Novel Markers with Spatially Distinct Patterning
Deborah M. Kurrasch, Clement C. Cheung, Florence Y. Lee, Phu V. Tran, Kenji Hata, Holly A. Ingraham
J Neurosci. 2007 Dec 12; 27(50): 13624–13634. doi: 10.1523/JNEUROSCI.2858-07.2007
PMCID:
PMC6673626
AbstractArticlePDF–638K
18.
Deletion of KCNQ2/3 potassium channels from PV+ interneurons leads to homeostatic potentiation of excitatory transmission
Heun Soh, Suhyeorn Park, Kali Ryan, Kristen Springer, Atul Maheshwari, Anastasios V Tzingounis
eLife. 2018; 7: e38617. Published online 2018 Nov 1. doi: 10.7554/eLife.38617
PMCID:
PMC6211828
AbstractArticlePDF–4.4M
19.
Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3)
Begoña Anta, Carlos Martín-Rodríguez, Carolina Gomis-Perez, Laura Calvo, Saray López-Benito, Andrés A. Calderón-García, Cristina Vicente-García, Álvaro Villarroel, Juan C. Arévalo
J Biol Chem. 2016 Sep 2; 291(36): 19132–19145. Published online 2016 Jul 21. doi: 10.1074/jbc.M116.722637
PMCID:
PMC5009282
AbstractArticlePDF–2.3M
20.
KCNQ channel openers reverse depressive symptoms via an active resilience mechanism
Allyson K. Friedman, Barbara Juarez, Stacy M. Ku, Hongxing Zhang, Rhodora C. Calizo, Jessica J. Walsh, Dipesh Chaudhury, Song Zhang, Angel Hawkins, David M. Dietz, James W. Murrough, Maria Ribadeneira, Erik H. Wong, Rachael L. Neve, Ming-Hu Han
Nat Commun. 2016; 7: 11671. Published online 2016 May 24. doi: 10.1038/ncomms11671
PMCID:
PMC4890180
AbstractArticlePDF–1.2M

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