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Select item 111064571.

Differential regulation of lung homeostasis and silicosis by the TAM receptors MerTk and Axl

Kamila Guimarães-Pinto, Monique Leandro, Antonia Corrêa, Ester P. Maia, Leticia Rodrigues, André Luiz Amorim da Costa, Jesuino Rafael Machado Ferreira, Estefannia Claudio-Etienne, Ulrich Siebenlist, Jianping He, Thaís da Silva Rigoni, Tatiana Paula Teixeira Ferreira, Yago Amigo Pinho Jannini-Sa, Herbert Leonel Matos-Guedes, Ana Caroline Costa-da-Silva, Marcela Freitas Lopes, Patricia Machado Rodrigues Silva, Brian Lee Kelsall, Alessandra Almeida Filardy

Front Immunol. 2024; 15: 1380628. Published online 2024 May 7. doi: 10.3389/fimmu.2024.1380628

PMCID:: PMC11106457

Abstract Article PDF–4.6M

Select item 105688772.

AXL receptor tyrosine kinase modulates gonadotropin-releasing hormone receptor signaling

Pardis Mohammadzadeh, Mina Roueinfar, Gregory C. Amberg

Cell Commun Signal. 2023; 21: 284. Published online 2023 Oct 12. doi: 10.1186/s12964-023-01313-y

PMCID:: PMC10568877

Abstract Article PDF–3.3M

Select item 103989213.

Receptor tyrosine kinases Tyro3, Axl, and Mertk differentially contribute to antibody-induced arthritis

Liang Gao, Chao He, Aizhen Yang, Haibin Zhou, Qingxian Lu, Raymond B. Birge, Yi Wu

Cell Commun Signal. 2023; 21: 195. Published online 2023 Aug 3. doi: 10.1186/s12964-023-01133-0

Correction in:: Cell Commun Signal. 2023; 21: 225.

PMCID:: PMC10398921

Abstract Article PDF–3.1M

Select item 103449624.

Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice

Vissarion Efthymiou, Lianggong Ding, Miroslav Balaz, Wenfei Sun, Lucia Balazova, Leon G. Straub, Hua Dong, Eric Simon, Adhideb Ghosh, Aliki Perdikari, Svenja Keller, Umesh Ghoshdastider, Carla Horvath, Caroline Moser, Bradford Hamilton, Heike Neubauer, Christian Wolfrum

Nat Commun. 2023; 14: 4162. Published online 2023 Jul 13. doi: 10.1038/s41467-023-39715-8

PMCID:: PMC10344962

Abstract Article PDF–4.6M

Select item 102090175.

AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells

Oltin-Tiberiu Pop, Anne Geng, Emilio Flint, Arjuna Singanayagam, Caner Ercan, Lucia Possamai, Vishal C. Patel, Patrizia Kuenzler, Marie-Anne Meier, Savas Soysal, Petr Hruz, Otto Kollmar, Kate C. Tatham, Josie K. Ward, Beat Müllhaupt, Achim Weber, Julia Wendon, Jan Hendrik Niess, Markus Heim, David Semela, Christopher Weston, Charalambos G. Antoniades, Luigi Maria Terracciano, Evangelos Triantafyllou, Robert G. Brenig, Christine Bernsmeier

Cell Mol Gastroenterol Hepatol. 2023; 16(1): 17–37. Published online 2023 Mar 31. doi: 10.1016/j.jcmgh.2023.03.007

PMCID:: PMC10209017

Abstract Article PDF–7.9M

Select item 102008756.

Axl promotes intracranial aneurysm rupture by regulating macrophage polarization toward M1 via STAT1/HIF-1α

Yongquan Han, Gaozhi Li, Zeyu Zhang, Xiaohua Zhang, Bing Zhao, Hua Yang

Front Immunol. 2023; 14: 1158758. Published online 2023 May 8. doi: 10.3389/fimmu.2023.1158758

PMCID:: PMC10200875

Abstract Article PDF–14M

Select item 100679637.

Axl alleviates DSS-induced colitis by preventing dysbiosis of gut microbiota

Su-Min Yee, Harim Choi, Jeong-Eun Seon, Yu-Jin Ban, Min-Jae Kim, Jae-Eun Seo, Ja Hun Seo, Sehyeon Kim, Seo Hee Moon, Chul-Ho Yun, Hyang Burm Lee, Hyung-Sik Kang

Sci Rep. 2023; 13: 5371. Published online 2023 Apr 1. doi: 10.1038/s41598-023-32527-2

PMCID:: PMC10067963

Abstract Article PDF–5.4M

Select item 99993658.

Axl and Mertk receptors cooperate to promote breast cancer progression by combined oncogenic signaling and evasion of host anti-tumor immunity

Viralkumar Davra, Sushil Kumar, Ke Geng, David Calianese, Dhriti Mehta, Varsha Gadiyar, Canan Kasikara, Kevin C. Lahey, Yun-juan Chang, Michael Wichroski, Chan Gao, Mariana S. De Lorenzo, Sergei V. Kotenko, Tessa Bergsbaken, Pankaj K. Mishra, William C. Gause, Michael Quigley, Thomas E. Spires, Raymond B. Birge

Cancer Res. Author manuscript; available in PMC 2023 Mar 10.

Published in final edited form as: Cancer Res. 2021 Feb 1; 81(3): 698–712. Published online 2020 Nov 25. doi: 10.1158/0008-5472.CAN-20-2066

PMCID:: PMC9999365

Abstract Article PDF–3.0M

Select item 98453559.

Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer

Bhasker Dharavath, Ashwin Butle, Ankita Pal, Sanket Desai, Pawan Upadhyay, Aishwarya Rane, Risha Khandelwal, Sujith Manavalan, Rahul Thorat, Kavita Sonawane, Richa Vaish, Poonam Gera, Munita Bal, Anil K. D’Cruz, Sudhir Nair, Amit Dutt

Commun Biol. 2023; 6: 57. Published online 2023 Jan 17. doi: 10.1038/s42003-023-04437-6

PMCID:: PMC9845355

Abstract Article PDF–2.1M

Select item 980058310.

Axl receptor induces efferocytosis, dampens M1 macrophage responses and promotes heart pathology in Trypanosoma cruzi infection

Thaís S. Rigoni, Natália S. Vellozo, Kamila Guimarães-Pinto, Mariela Cabral-Piccin, Laryssa Fabiano-Coelho, Thayane C. Matos-Silva, Alessandra A. Filardy, Christina M. Takiya, Marcela F. Lopes

Commun Biol. 2022; 5: 1421. Published online 2022 Dec 29. doi: 10.1038/s42003-022-04401-w

PMCID:: PMC9800583

Abstract Article PDF–9.7M

Select item 960271511.

Role of Axl in target organ inflammation and damage due to hypertensive aortic remodeling

Wei Chen, Justin P. Van Beusecum, Liang Xiao, David M. Patrick, Mingfang Ao, Shilin Zhao, Marcos G. Lopez, Frederic T. Billings, 4th, Cristina Cavinato, Alexander W. Caulk, Jay D. Humphrey, David G. Harrison

Am J Physiol Heart Circ Physiol. 2022 Nov 1; 323(5): H917–H933. Published online 2022 Sep 9. doi: 10.1152/ajpheart.00253.2022

PMCID:: PMC9602715

Abstract Article

Select item 937372612.

The TAM receptor tyrosine kinases Axl and Mer drive the maintenance of highly phagocytic macrophages

Lidia Jiménez-García, Christopher Mayer, Patrick G. Burrola, Youtong Huang, Maxim N. Shokhirev, Greg Lemke

Front Immunol. 2022; 13: 960401. Published online 2022 Jul 29. doi: 10.3389/fimmu.2022.960401

PMCID:: PMC9373726

Abstract Article PDF–19M

Select item 921308213.

Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression

Zhen Wang, Deng Liu, Qi Yan, Fang Liu, Mengting Zhan, Shunli Qi, Qi Fang, Lei Yao, Weizhi Wang, Ruixin Zhang, Jian Du, Lijian Chen

Transplantation. 2022 Jul; 106(7): 1351–1364. Published online 2022 May 11. doi: 10.1097/TP.0000000000004156

PMCID:: PMC9213082

Abstract Article PDF–7.2M

Select item 907126614.

Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence

Sarah Rose Anderson, Jacqueline M Roberts, Nathaniel Ghena, Emmalyn A Irvin, Joon Schwakopf, Isabelle B Cooperstein, Alejandra Bosco, Monica L Vetter

eLife. 2022; 11: e76564. Published online 2022 Apr 28. doi: 10.7554/eLife.76564

PMCID:: PMC9071266

Abstract Article PDF–14M

Select item 894121215.

Counteractive and cooperative actions of muscle β-catenin and Ca_V1.1 during early neuromuscular synapse formation

Mehmet Mahsum Kaplan, Bernhard E. Flucher

iScience. 2022 Apr 15; 25(4): 104025. Published online 2022 Mar 4. doi: 10.1016/j.isci.2022.104025

PMCID:: PMC8941212

Abstract Article PDF–6.5M

Select item 845687916.

Targeting the AXL Receptor in Combating Smoking-related Pulmonary Fibrosis

David C. Yang, Shenwen Gu, Ji-Min Li, Ssu-Wei Hsu, Szu-Jung Chen, Wen-Hsin Chang, Ching-Hsien Chen

Am J Respir Cell Mol Biol. 2021 Jun; 64(6): 734–746. Published online 2021 Mar 17. doi: 10.1165/rcmb.2020-0303OC

PMCID:: PMC8456879

Abstract Article PDF–3.1M

Select item 834982717.

AXL is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

Wenting Du, Natalie Z. Phinney, Huocong Huang, Zhaoning Wang, Jill Westcott, Jason E. Toombs, Yuqing Zhang, Muhammad S. Beg, Thomas M. Wilkie, James B. Lorens, Rolf A. Brekken

Mol Cancer Res. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Mol Cancer Res. 2021 Aug; 19(8): 1412–1421. Published online 2021 Apr 2. doi: 10.1158/1541-7786.MCR-20-0860

PMCID:: PMC8349827

Abstract Article PDF–2.6M

Select item 831323918.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 830738119.

Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels

Marie-Anne Goyette, Islam E. Elkholi, Chloé Apcher, Hellen Kuasne, Carla V. Rothlin, William J. Muller, Darren E. Richard, Morag Park, Jean-Philippe Gratton, Jean-François Côté

Proc Natl Acad Sci U S A. 2021 Jul 20; 118(29): e2023868118. Published online 2021 Jul 15. doi: 10.1073/pnas.2023868118

PMCID:: PMC8307381

Abstract Article PDF–6.0M

Select item 826499320.

AXL kinase-mediated astrocytic phagocytosis modulates outcomes of traumatic brain injury

Hang Zhou, Libin Hu, Jianru Li, Wu Ruan, Yang Cao, Jianfeng Zhuang, Hangzhe Xu, Yucong Peng, Zhongyuan Zhang, Chaoran Xu, Qian Yu, Yin Li, Zhangqi Dou, Junwen Hu, Xinyan Wu, Xiaobo Yu, Chi Gu, Shenglong Cao, Feng Yan, Gao Chen

J Neuroinflammation. 2021; 18: 154. Published online 2021 Jul 7. doi: 10.1186/s12974-021-02201-3

PMCID:: PMC8264993

Abstract Article PDF–7.4M

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