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Items: 1 to 20 of 76

1.
FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development
Jing Ji, Qilan Qian, Wenhao Cheng, Xiaoqing Ye, Aixin Jing, Shaojie Ma, Yuanyuan Ding, Xinhui Ma, Yasong Wang, Qian Sun, Xiujun Wang, Yulu Chen, Lan Zhu, Qing Yuan, Menghan Xu, Jingting Qin, Lin Ma, Jiayan Yang, Meiqi Zhang, Ting Geng, Sen Wang, Dan Wang, Yizhuo Song, Boyu Zhang, Yuting Xu, Linyu Xu, Shunfang Liu, Wei Liu, Bin Liu
Cell Death Dis. 2024 May; 15(5): 332. Published online 2024 May 13. doi: 10.1038/s41419-024-06713-7
PMCID:
PMC11091054
AbstractArticlePDF–4.6M
2.
Knockdown of PTK7 Reduces the Oncogenic Potential of Breast Cancer Cells by Impeding Receptor Tyrosine Kinase Signaling
Won-Sik Shin, Si Won Oh, Han Na Park, Jae Hoon Kim, Seung-Taek Lee
Int J Mol Sci. 2023 Aug; 24(15): 12173. Published online 2023 Jul 29. doi: 10.3390/ijms241512173
PMCID:
PMC10418930
AbstractArticlePDF–2.1M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
5.
Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2
Annarita Miluzio, Alessandro Cuomo, Chiara Cordiglieri, Lorena Donnici, Elisa Pesce, Mauro Bombaci, Matteo Conti, Alessandra Fasciani, Luigi Terracciano, Lara Manganaro, Mirco Toccafondi, Alessandra Scagliola, Stefania Oliveto, Sara Ricciardi, Renata Grifantini, Raffaele De Francesco, Sergio Abrignani, Nicola Manfrini, Stefano Biffo
eBioMedicine. 2023 Jan; 87: 104390. Published online 2022 Dec 28. doi: 10.1016/j.ebiom.2022.104390
PMCID:
PMC9795807
AbstractArticlePDF–4.6M
6.
Diverse ancestry whole-genome sequencing association study identifies TBX5 and PTK7 as susceptibility genes for posterior urethral valves
Melanie MY Chan, Omid Sadeghi-Alavijeh, Filipa M Lopes, Alina C Hilger, Horia C Stanescu, Catalin D Voinescu, Glenda M Beaman, William G Newman, Marcin Zaniew, Stefanie Weber, Yee Mang Ho, John O Connolly, Dan Wood, Carlo Maj, Alexander Stuckey, Athanasios Kousathanas, Genomics England Research Consortium, Robert Kleta, Adrian S Woolf, Detlef Bockenhauer, Adam P Levine, Daniel P Gale
eLife. 2022; 11: e74777. Published online 2022 Sep 20. doi: 10.7554/eLife.74777
PMCID:
PMC9512401
AbstractArticlePDF–5.7M
7.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
8.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
9.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
10.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
11.
High expression of protein tyrosine kinase 7 in oral squamous cell carcinoma: Clinicopathological correlation and prognosis relevance
Yujiro Kimura, Kunio Yoshizawa, Asami Hotta‐Osada, Akinori Moroi, Hiroki Ishii, Daiju Sakurai, Masao Saitoh, Naoki Oishi, Tetsuo Kondo, Koichiro Ueki
Clin Exp Dent Res. 2022 Apr; 8(2): 506–512. Published online 2022 Mar 8. doi: 10.1002/cre2.553
PMCID:
PMC9033537
AbstractArticlePDF–1.3M
12.
PTK7, a Catalytically Inactive Receptor Tyrosine Kinase, Increases Oncogenic Phenotypes in Xenograft Tumors of Esophageal Squamous Cell Carcinoma KYSE-30 Cells
Won-Sik Shin, Mi-Kyung Park, Jae Hoon Kim, Si Won Oh, Ji-Yun Jang, Ho Lee, Seung-Taek Lee
Int J Mol Sci. 2022 Feb; 23(4): 2391. Published online 2022 Feb 21. doi: 10.3390/ijms23042391
PMCID:
PMC8876147
AbstractArticlePDF–35M
13.
Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network
Rebecca Elizabeth Kattan, Han Han, Gayoung Seo, Bing Yang, Yongqi Lin, Max Dotson, Stephanie Pham, Yahya Menely, Wenqi Wang
Mol Cell Proteomics. 2022 Feb; 21(2): 100195. Published online 2022 Jan 8. doi: 10.1016/j.mcpro.2022.100195
PMCID:
PMC8864472
AbstractArticlePDF–3.6M
14.
Whole-Exome Sequencing Identifies a Novel Germline Variant in PTK7 Gene in Familial Colorectal Cancer
Beiping Miao, Diamanto Skopelitou, Aayushi Srivastava, Sara Giangiobbe, Dagmara Dymerska, Nagarajan Paramasivam, Abhishek Kumar, Magdalena Kuświk, Wojciech Kluźniak, Katarzyna Paszkowska-Szczur, Matthias Schlesner, Jan Lubinski, Kari Hemminki, Asta Försti, Obul Reddy Bandapalli
Int J Mol Sci. 2022 Feb; 23(3): 1295. Published online 2022 Jan 24. doi: 10.3390/ijms23031295
PMCID:
PMC8836109
AbstractArticlePDF–3.5M
15.
The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis
Zhe Su, Yang Yang, Shengru Wang, Sen Zhao, Hengqiang Zhao, Xiaoxin Li, Yuchen Niu, Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) Study Group, Guixing Qiu, Zhihong Wu, Nan Wu, Terry Jianguo Zhang
Genes (Basel) 2021 Nov; 12(11): 1791. Published online 2021 Nov 12. doi: 10.3390/genes12111791
PMCID:
PMC8619039
AbstractArticlePDF–1.5M
16.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
17.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
18.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
19.
Oncogenic role of protein tyrosine kinase 7 in esophageal squamous cell carcinoma
Won‐Sik Shin, Junhye Kwon, Hae Won Lee, Moon Chul Kang, Hye‐Won Na, Seung‐Taek Lee, Jong Ho Park
Cancer Sci. 2013 Aug; 104(8): 1120–1126. Published online 2013 Jun 13. doi: 10.1111/cas.12194
PMCID:
PMC7657253
AbstractArticlePDF–1.0M
20.
Structural insights into pseudokinase domains of receptor tyrosine kinases
Joshua B. Sheetz, Sebastian Mathea, Hanna Karvonen, Ketan Malhotra, Deep Chatterjee, Wilhelmiina Niininen, Robert Perttilä, Franziska Preuss, Krishna Suresh, Steven E. Stayrook, Yuko Tsutsui, Ravi Radhakrishnan, Daniela Ungureanu, Stefan Knapp, Mark A. Lemmon
Mol Cell. Author manuscript; available in PMC 2021 Aug 6.
Published in final edited form as: Mol Cell. 2020 Aug 6; 79(3): 390–405.e7. Published online 2020 Jul 2. doi: 10.1016/j.molcel.2020.06.018
PMCID:
PMC7543951
AbstractArticlePDF–3.0M

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