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Select item 111281961.

FLRT2 prevents endothelial cell senescence and vascular aging by regulating the ITGB4/mTORC2/p53 signaling pathway

Hyun Jung Hwang, Donghee Kang, Jae-Ryong Kim, Joon Hyuk Choi, Ji-Kan Ryu, Allison B. Herman, Young-Gyu Ko, Heon Joo Park, Myriam Gorospe, Jae-Seon Lee

JCI Insight. 2024 Apr 8; 9(7): e172678. Published online 2024 Apr 8. doi: 10.1172/jci.insight.172678

PMCID:: PMC11128196

Abstract Article PDF–13M

Select item 111011122.

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development

Kif Liakath-Ali, Rebecca Refaee, Thomas C. Südhof

PLoS Biol. 2024 May; 22(5): e3002599. Published online 2024 May 7. doi: 10.1371/journal.pbio.3002599

PMCID:: PMC11101112

Abstract Article PDF–9.1M

Select item 107034193.

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson

PLoS Genet. 2023 Nov; 19(11): e1010777. Published online 2023 Nov 27. doi: 10.1371/journal.pgen.1010777

PMCID:: PMC10703419

Abstract Article PDF–9.6M

Select item 101176574.

Fibronectin leucine-rich transmembrane protein 2 drives monocyte differentiation into macrophages via the UNC5B-Akt/mTOR axis

Yaxiong Fang, Kongyang Ma, Yi-Min Huang, Yuanye Dang, Zhaoyu Liu, Yiming Xu, Xi-Long Zheng, Xiangdong Yang, Yongliang Huo, Xiaoyan Dai

Front Immunol. 2023; 14: 1162004. Published online 2023 Apr 6. doi: 10.3389/fimmu.2023.1162004

PMCID:: PMC10117657

Abstract Article PDF–13M

Select item 95120815.

Autism risk gene POGZ promotes chromatin accessibility and expression of clustered synaptic genes

Eirene Markenscoff-Papadimitriou, Fadya Binyameen, Sean Whalen, James Price, Kenneth Lim, Athena R. Ypsilanti, Rinaldo Catta-Preta, Emily Ling-Lin Pai, Xin Mu, Duan Xu, Katherine S. Pollard, Alex S. Nord, Matthew W. State, John L. Rubenstein

Cell Rep. Author manuscript; available in PMC 2022 Sep 26.

Published in final edited form as: Cell Rep. 2021 Dec 7; 37(10): 110089. doi: 10.1016/j.celrep.2021.110089

PMCID:: PMC9512081

Abstract Article PDF–2.6M

Select item 89203446.

Tumor-specific interendothelial adhesion mediated by FLRT2 facilitates cancer aggressiveness

Tomofumi Ando, Ikue Tai-Nagara, Yuki Sugiura, Dai Kusumoto, Koji Okabayashi, Yasuaki Kido, Kohji Sato, Hideyuki Saya, Sutip Navankasattusas, Dean Y. Li, Makoto Suematsu, Yuko Kitagawa, Elena Seiradake, Satoru Yamagishi, Yoshiaki Kubota

J Clin Invest. 2022 Mar 15; 132(6): e153626. Published online 2022 Mar 15. doi: 10.1172/JCI153626

PMCID:: PMC8920344

Abstract Article PDF–6.9M

Select item 88879037.

Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

Dongjin R Lee, Christopher Rhodes, Apratim Mitra, Yajun Zhang, Dragan Maric, Ryan K Dale, Timothy J Petros

eLife. 2022; 11: e71864. Published online 2022 Feb 17. doi: 10.7554/eLife.71864

PMCID:: PMC8887903

Abstract Article PDF–15M

Select item 87868368.

Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development

Margaret E. Magaletta, Macrina Lobo, Eric M. Kernfeld, Hananeh Aliee, Jack D. Huey, Teagan J. Parsons, Fabian J. Theis, René Maehr

Nat Commun. 2022; 13: 457. Published online 2022 Jan 24. doi: 10.1038/s41467-022-28067-4

PMCID:: PMC8786836

Abstract Article PDF–5.6M

Select item 86960379.

FLRT3 Marks Direction-Selective Retinal Ganglion Cells That Project to the Medial Terminal Nucleus

Tobias Ruff, Christian Peters, Akihiro Matsumoto, Stephan J. Ihle, Pilar Alcalá Morales, Louise Gaitanos, Keisuke Yonehara, Daniel del Toro, Rüdiger Klein

Front Mol Neurosci. 2021; 14: 790466. Published online 2021 Dec 9. doi: 10.3389/fnmol.2021.790466

PMCID:: PMC8696037

Abstract Article PDF–4.8M

Select item 856925710.

Expression of FLRT2 in Postnatal Central Nervous System Development and After Spinal Cord Injury

Juntan Li, Yo Shinoda, Shuhei Ogawa, Shunsuke Ikegaya, Shuo Li, Yukihiro Matsuyama, Kohji Sato, Satoru Yamagishi

Front Mol Neurosci. 2021; 14: 756264. Published online 2021 Oct 22. doi: 10.3389/fnmol.2021.756264

PMCID:: PMC8569257

Abstract Article PDF–4.8M

Select item 841298311.

FLRT2 and FLRT3 Cooperate in Maintaining the Tangential Migratory Streams of Cortical Interneurons during Development

Catherine Fleitas, Pau Marfull-Oromí, Disha Chauhan, Daniel del Toro, Blanca Peguera, Bahira Zammou, Daniel Rocandio, Rüdiger Klein, Carme Espinet, Joaquim Egea

J Neurosci. 2021 Sep 1; 41(35): 7350–7362. doi: 10.1523/JNEUROSCI.0380-20.2021

PMCID:: PMC8412983

Abstract Article PDF–3.7M

Select item 831323912.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 806361613.

Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts

Fengling Chen, Jiewen Chen, Hong Wang, Huayuan Tang, Lei Huang, Shijia Wang, Xinru Wang, Xi Fang, Jie Liu, Li Li, Kunfu Ouyang, Zhen Han

Front Cell Dev Biol. 2021; 9: 651655. Published online 2021 Apr 9. doi: 10.3389/fcell.2021.651655

PMCID:: PMC8063616

Abstract Article PDF–4.0M

Select item 737738714.

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalenceof Germline Recombination and Influencing Factors

Lin Luo, Mateusz C. Ambrozkiewicz, Fritz Benseler, Cui Chen, Emilie Dumontier, Susanne Falkner, Elisabetta Furlanis, Andrea M. Gomez, Naosuke Hoshina, Wei-Hsiang Huang, Mary Anne Hutchison, Yu Itoh-Maruoka, Laura A. Lavery, Wei Li, Tomohiko Maruo, Junko Motohashi, Emily Ling-Lin Pai, Kenneth A. Pelkey, Ariane Pereira, Thomas Philips, Jennifer L. Sinclair, Jeff A. Stogsdill, Lisa Traunmüller, Jiexin Wang, Joke Wortel, Wenjia You, Nashat Abumaria, Kevin T. Beier, Nils Brose, Harold A. Burgess, Constance L. Cepko, Jean-François Cloutier, Cagla Eroglu, Sandra Goebbels, Pascal S. Kaeser, Jeremy N. Kay, Wei Lu, Liqun Luo, Kenji Mandai, Chris J. McBain, Klaus-Armin Nave, Marco A.M. Prado, Vania F. Prado, Jeffrey Rothstein, John L.R. Rubenstein, Gesine Saher, Kenji Sakimura, Joshua R. Sanes, Peter Scheiffele, Yoshimi Takai, Hisashi Umemori, Matthijs Verhage, Michisuke Yuzaki, Huda Yahya Zoghbi, Hiroshi Kawabe, Ann Marie Craig

Neuron. Author manuscript; available in PMC 2021 Apr 8.

Published in final edited form as: Neuron. 2020 Apr 8; 106(1): 37–65.e5. Published online 2020 Feb 5. doi: 10.1016/j.neuron.2020.01.008

PMCID:: PMC7377387

Abstract Article PDF–2.3M

Select item 697880115.

Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons

Daniel del Toro, Maria A. Carrasquero-Ordaz, Amy Chu, Tobias Ruff, Meriam Shahin, Verity A. Jackson, Matthieu Chavent, Miguel Berbeira-Santana, Goenuel Seyit-Bremer, Sara Brignani, Rainer Kaufmann, Edward Lowe, Rüdiger Klein, Elena Seiradake

Cell. 2020 Jan 23; 180(2): 323–339.e19. doi: 10.1016/j.cell.2019.12.014

PMCID:: PMC6978801

Abstract Article

Select item 672620816.

Flrt2 is involved in fine-tuning of osteoclast multinucleation

Jumpei Shirakawa, Noriko Takegahara, Hyunsoo Kim, Seoung Hoon Lee, Kohji Sato, Satoru Yamagishi, Yongwon Choi

BMB Rep. 2019 Aug; 52(8): 514–519. Published online 2019 Aug 31. doi: 10.5483/BMBRep.2019.52.8.116

PMCID:: PMC6726208

Abstract Article PDF–8.1M

Select item 638138817.

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System

Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund

Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005

PMCID:: PMC6381388

Abstract Article

Select item 582922918.

Enhanced synaptic plasticity and spatial memory in female but not male FLRT2-haplodeficient mice

Ana Cicvaric, Jiaye Yang, Tanja Bulat, Alice Zambon, Manuel Dominguez-Rodriguez, Rebekka Kühn, Michael G. Sadowicz, Anjana Siwert, Joaquim Egea, Daniela D. Pollak, Thomas Moeslinger, Francisco J. Monje

Sci Rep. 2018; 8: 3703. Published online 2018 Feb 27. doi: 10.1038/s41598-018-22030-4

PMCID:: PMC5829229

Abstract Article PDF–2.8M

Select item 538122619.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 483887820.

Super-complexes of adhesion GPCRs and neural guidance receptors

Verity A. Jackson, Shahid Mehmood, Matthieu Chavent, Pietro Roversi, Maria Carrasquero, Daniel del Toro, Goenuel Seyit-Bremer, Fanomezana M. Ranaivoson, Davide Comoletti, Mark S. P. Sansom, Carol V. Robinson, Rüdiger Klein, Elena Seiradake

Nat Commun. 2016; 7: 11184. Published online 2016 Apr 19. doi: 10.1038/ncomms11184

PMCID:: PMC4838878

Abstract Article PDF–2.8M

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