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Select item 111590871.

Significance of error‐avoiding mechanisms for oxidative DNA damage in carcinogenesis

Teruhisa Tsuzuki, Yoshimichi Nakatsu, Yusaku Nakabeppu

Cancer Sci. 2007 Apr; 98(4): 465–470. Published online 2007 Jan 19. doi: 10.1111/j.1349-7006.2007.00409.x

PMCID:: PMC11159087

Abstract Article PDF–207K

Select item 111584682.

Carcinogenicity of dimethylarsinic acid in Ogg1‐deficient mice

Anna Kinoshita, Hideki Wanibuchi, Keiichirou Morimura, Min Wei, Dai Nakae, Tsuyoshi Arai, Osamu Minowa, Tetsuo Noda, Susumu Nishimura, Shoji Fukushima

Cancer Sci. 2007 Jun; 98(6): 803–814. Published online 2007 Apr 18. doi: 10.1111/j.1349-7006.2007.00475.x

PMCID:: PMC11158468

Abstract Article PDF–583K

Select item 111436563.

Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy

Wenjuan Wu, Hongxia Jia, Song Chen, Xinran Ma, Shuai Zhou, Lingxiao Qiu, Xinhui Wu, Ping Li, Heying Chu, Guojun Zhang

Mol Med. 2024; 30: 72. Published online 2024 May 31. doi: 10.1186/s10020-024-00843-6

PMCID:: PMC11143656

Abstract Article PDF–8.8M

Select item 110729904.

Excessive iron inhibits insulin secretion via perturbing transcriptional regulation of SYT7 by OGG1

Xingqi Zhao, Ying Ma, Munan Shi, Miaoling Huang, Jingyu Xin, Shusheng Ci, Meimei Chen, Tao Jiang, Zhigang Hu, Lingfeng He, Feiyan Pan, Zhigang Guo

Cell Mol Life Sci. 2023 Jun; 80(6): 159. Published online 2023 May 20. doi: 10.1007/s00018-023-04802-y

PMCID:: PMC11072990

Abstract Article PDF–12M

Select item 106411715.

8-Oxoguanine DNA glycosylase 1 selectively modulates ROS-responsive NF-κB targets through recruitment of MSK1 and phosphorylation of RelA/p65 at Ser276

Yaoyao Xue, Chunshuang Li, Shihua Deng, Xin Chen, Jinling Han, Xu Zheng, Miaomiao Tian, Wenjing Hao, Lang Pan, Istvan Boldogh, Xueqing Ba, Ruoxi Wang

J Biol Chem. 2023 Nov; 299(11): 105308. Published online 2023 Sep 29. doi: 10.1016/j.jbc.2023.105308

PMCID:: PMC10641171

Abstract Article PDF–5.1M

Select item 104365566.

Epigenetic control of type III interferon expression by 8-oxoguanine and its reader 8-oxoguanine DNA glycosylase1

Yaoyao Xue, Lang Pan, Spiros Vlahopoulos, Ke Wang, Xu Zheng, Zsolt Radak, Attila Bacsi, Lloyd Tanner, Allan R. Brasier, Xueqing Ba, Istvan Boldogh

Front Immunol. 2023; 14: 1161160. Published online 2023 Aug 4. doi: 10.3389/fimmu.2023.1161160

PMCID:: PMC10436556

Abstract Article PDF–10M

Select item 102996417.

The Role of Annexin A1 in DNA Damage Response in Placental Cells: Impact on Gestational Diabetes Mellitus

Jusciele Brogin Moreli, Mayk Ricardo dos Santos, Iracema de Mattos Paranhos Calderon, Cristina Bichels Hebeda, Sandra Helena Poliselli Farsky, Estela Bevilacqua, Sonia Maria Oliani

Int J Mol Sci. 2023 Jun; 24(12): 10155. Published online 2023 Jun 15. doi: 10.3390/ijms241210155

PMCID:: PMC10299641

Abstract Article PDF–11M

Select item 101922088.

Genome-wide analysis of sex-specific differences in the mother–child PELAGIE cohort exposed to organophosphate metabolites

Martina Capriati, Chunxiang Hao, Shereen Cynthia D’Cruz, Christine Monfort, Cecile Chevrier, Charline Warembourg, Fatima Smagulova

Sci Rep. 2023; 13: 8003. Published online 2023 May 17. doi: 10.1038/s41598-023-35113-8

PMCID:: PMC10192208

Abstract Article PDF–3.0M

Select item 99436619.

8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injury

Lang Pan, Wenjing Hao, Yaoyao Xue, Ke Wang, Xu Zheng, Jixian Luo, Xueqing Ba, Yang Xiang, Xiaoqun Qin, Jesper Bergwik, Lloyd Tanner, Arne Egesten, Allan R Brasier, Istvan Boldogh

Nucleic Acids Res. 2023 Feb 22; 51(3): 1087–1102. Published online 2023 Jan 18. doi: 10.1093/nar/gkac1241

PMCID:: PMC9943661

Abstract Article PDF–19M

Select item 954575610.

Targeting the DNA repair enzymes MTH1 and OGG1 as a novel approach to treat inflammatory diseases

Stella Karsten

Basic Clin Pharmacol Toxicol. 2022 Aug; 131(2): 95–103. Published online 2022 Jun 24. doi: 10.1111/bcpt.13765

PMCID:: PMC9545756

Abstract Article PDF–8.8M

Select item 863528511.

DNA Glycosylase Deficiency Leads to Decreased Severity of Lupus in the Polb-Y265C Mouse Model

Sesha L. Paluri, Matthew Burak, Alireza G. Senejani, Madison Levinson, Tania Rahim, Kaylyn Clairmont, Michael Kashgarian, Isabel Alvarado-Cruz, Rithy Meas, Marina Cardó-Vila, Caroline Zeiss, Stephen Maher, Alfred L.M. Bothwell, Erdem Coskun, Melis Kant, Pawel Jaruga, Miral Dizdaroglu, R. Stephen Lloyd, Joann B. Sweasy

DNA Repair (Amst) Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: DNA Repair (Amst). 2021 Sep; 105: 103152. Published online 2021 Jun 24. doi: 10.1016/j.dnarep.2021.103152

PMCID:: PMC8635285

Abstract Article PDF–1.5M

Select item 846524412.

Oxidative Stress, Mutations and Chromosomal Aberrations Induced by In Vitro and In Vivo Exposure to Furan

Maria Teresa Russo, Gabriele De Luca, Nieves Palma, Paola Leopardi, Paolo Degan, Serena Cinelli, Gaetano Pepe, Pasquale Mosesso, Emma Di Carlo, Carlo Sorrentino, Piero Musiani, Riccardo Crebelli, Margherita Bignami, Eugenia Dogliotti

Int J Mol Sci. 2021 Sep; 22(18): 9687. Published online 2021 Sep 7. doi: 10.3390/ijms22189687

PMCID:: PMC8465244

Abstract Article PDF–3.5M

Select item 798812913.

MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis

Sugako Oka, Julio Leon, Kunihiko Sakumi, Nona Abolhassani, Zijing Sheng, Daisuke Tsuchimoto, Frank M. LaFerla, Yusaku Nakabeppu

Sci Rep. 2021; 11: 5819. Published online 2021 Mar 23. doi: 10.1038/s41598-021-84640-9

PMCID:: PMC7988129

Abstract Article PDF–12M

Select item 786574314.

A Novel Role for the DNA Repair Enzyme 8-Oxoguanine DNA Glycosylase in Adipogenesis

Sai Santosh Babu Komakula, Bhavya Blaze, Hong Ye, Agnieszka Dobrzyn, Harini Sampath

Int J Mol Sci. 2021 Feb; 22(3): 1152. Published online 2021 Jan 25. doi: 10.3390/ijms22031152

PMCID:: PMC7865743

Abstract Article PDF–2.6M

Select item 754192015.

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

Gantsetseg Tumurkhuu, Shuang Chen, Erica N. Montano, Duygu Ercan Laguna, Gabriela De Los Santos, Jeong Min Yu, Malcolm Lane, Michifumi Yamashita, Janet L. Markman, Luz P. Blanco, Mariana J. Kaplan, Kenichi Shimada, Timothy R. Crother, Mariko Ishimori, Daniel J. Wallace, Caroline A. Jefferies, Moshe Arditi

Front Immunol. 2020; 11: 554725. Published online 2020 Sep 24. doi: 10.3389/fimmu.2020.554725

PMCID:: PMC7541920

Abstract Article PDF–2.4M

Select item 754174216.

Small Molecule Inhibitor of 8-oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during P. aeruginosa Infection

Shugang Qin, Ping Lin, Qun Wu, Qinqin Pu, Chuanmin Zhou, Biao Wang, Pan Gao, Zhihan Wang, Ashley Gao, Madison Overby, Jinliang Yang, Jianxin Jiang, David L. Wilson, Yu-ki Tahara, Eric T. Kool, Zhenwei Xia, Min Wu

J Immunol. Author manuscript; available in PMC 2021 Oct 15.

Published in final edited form as: J Immunol. 2020 Oct 15; 205(8): 2231–2242. Published online 2020 Sep 14. doi: 10.4049/jimmunol.1901533

PMCID:: PMC7541742

Abstract Article PDF–2.3M

Select item 727273217.

Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis

Seok-Jo Kim, Paul Cheresh, Renea P. Jablonski, Lyudmila Rachek, Anjana Yeldandi, Raul Piseaux-Aillon, Mark J. Ciesielski, Karen Ridge, Cara Gottardi, Anna P. Lam, Annie Pardo, Moises Selman, Viswanathan Natarajan, David W. Kamp

Am J Physiol Lung Cell Mol Physiol. 2020 May 1; 318(5): L1084–L1096. Published online 2020 Mar 25. doi: 10.1152/ajplung.00069.2019

PMCID:: PMC7272732

Abstract Article

Select item 723504318.

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease

Ping-Chieh Pao, Debasis Patnaik, L. Ashley Watson, Fan Gao, Ling Pan, Jun Wang, Chinnakkaruppan Adaikkan, Jay Penney, Hugh P. Cam, Wen-Chin Huang, Lorena Pantano, Audrey Lee, Alexi Nott, Trongha X. Phan, Elizabeta Gjoneska, Sara Elmsaouri, Stephen J. Haggarty, Li-Huei Tsai

Nat Commun. 2020; 11: 2484. Published online 2020 May 18. doi: 10.1038/s41467-020-16361-y

PMCID:: PMC7235043

Abstract Article PDF–3.0M

Select item 695958319.

OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model

Holly Simon, Vladimir Vartanian, Melissa H. Wong, Yusaku Nakabeppu, Priyanka Sharma, R. Stephen Lloyd, Harini Sampath

PLoS One. 2020; 15(1): e0227501. Published online 2020 Jan 14. doi: 10.1371/journal.pone.0227501

PMCID:: PMC6959583

Abstract Article PDF–2.4M

Select item 693986120.

Roles of OGG1 in Transcriptional Regulation and Maintenance of Metabolic Homeostasis

Harini Sampath, R. Stephen Lloyd

DNA Repair (Amst) Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: DNA Repair (Amst). 2019 Sep; 81: 102667. Published online 2019 Jul 8. doi: 10.1016/j.dnarep.2019.102667

PMCID:: PMC6939861

Abstract Article PDF–563K

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