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Items: 1 to 20 of 29

1.
Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation
Leonid A. Parunov, Yideng Liang, Qijin Lu, Alexey M. Shibeko, Erik I. Tucker, Timothy K. Lee, Fazoil I. Ataullakhanov, Dorothy E. Scott, Mikhail V. Ovanesov
Blood Adv. 2023 Jun 13; 7(11): 2622–2631. Published online 2023 Feb 3. doi: 10.1182/bloodadvances.2022008743
PMCID:
PMC10250917
AbstractArticlePDF–1.2M
2.
A non-circulating pool of factor XI associated with glycosaminoglycans in mice
Bassem M. Mohammed, Qiufang Cheng, Anton Matafonov, Ingrid M. Verhamme, Jonas Emsley, Keith R. McCrae, Owen J. T. McCarty, Andras Gruber, David Gailani
J Thromb Haemost. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: J Thromb Haemost. 2019 Sep; 17(9): 1449–1460. Published online 2019 Jun 17. doi: 10.1111/jth.14494
PMCID:
PMC6768408
AbstractArticlePDF–850K
3.
A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain
Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Bassem M. Mohammed, Qiufang Cheng, S. Kent Dickeson, Suman Kundu, Ingrid M. Verhamme, Andras Gruber, Keith McCrae, David Gailani
Blood. 2019 Mar 7; 133(10): 1152–1163. Prepublished online 2018 Dec 27. doi: 10.1182/blood-2018-06-860270
PMCID:
PMC6405335
AbstractArticle
4.
Factor XI contributes to myocardial ischemia-reperfusion injury in mice
Christina U. Lorentz, Norah G. Verbout, Zhiping Cao, Lijuan Liu, Monica T. Hinds, Owen J. T. McCarty, Ivan Ivanov, Erik I. Tucker, David Gailani, András Gruber
Blood Adv. 2018 Jan 23; 2(2): 85–88. Published online 2018 Jan 10. doi: 10.1182/bloodadvances.2017004879
PMCID:
PMC5787867
AbstractArticlePDF–753K
5.
Neutralizing blood-borne polyphosphate in vivo provides safe thromboprotection
Linda Labberton, Ellinor Kenne, Andy T. Long, Katrin F. Nickel, Antonio Di Gennaro, Rachel A. Rigg, James S. Hernandez, Lynn Butler, Coen Maas, Evi X. Stavrou, Thomas Renné
Nat Commun. 2016; 7: 12616. Published online 2016 Sep 6. doi: 10.1038/ncomms12616
PMCID:
PMC5025862
AbstractArticlePDF–3.4M
6.
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells
Kerstin Göbel, Susann Pankratz, Chloi-Magdalini Asaridou, Alexander M. Herrmann, Stefan Bittner, Monika Merker, Tobias Ruck, Sarah Glumm, Friederike Langhauser, Peter Kraft, Thorsten F. Krug, Johanna Breuer, Martin Herold, Catharina C. Gross, Denise Beckmann, Adelheid Korb-Pap, Michael K. Schuhmann, Stefanie Kuerten, Ioannis Mitroulis, Clemens Ruppert, Marc W. Nolte, Con Panousis, Luisa Klotz, Beate Kehrel, Thomas Korn, Harald F. Langer, Thomas Pap, Bernhard Nieswandt, Heinz Wiendl, Triantafyllos Chavakis, Christoph Kleinschnitz, Sven G. Meuth
Nat Commun. 2016; 7: 11626. Published online 2016 May 18. doi: 10.1038/ncomms11626
PMCID:
PMC4873982
AbstractArticlePDF–1.5M
7.
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice
Charles E. Bane, Jr, Ivan Ivanov, Anton Matafonov, Kelli L. Boyd, Qiufang Cheng, Edward R. Sherwood, Erik I. Tucker, Stephen T. Smiley, Owen J. T. McCarty, Andras Gruber, David Gailani
PLoS One. 2016; 11(4): e0152968. Published online 2016 Apr 5. doi: 10.1371/journal.pone.0152968
PMCID:
PMC4821616
AbstractArticlePDF–1.7M
8.
Thrombin-independent contribution of tissue factor to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease
Erica M. Sparkenbaugh, Pichika Chantrathammachart, Kasemsiri Chandarajoti, Nigel Mackman, Nigel S. Key, Rafal Pawlinski
Blood. 2016 Mar 10; 127(10): 1371–1373. doi: 10.1182/blood-2015-11-681114
PMCID:
PMC4786843
Article
9.
Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout Mice
Reut Shnerb Ganor, Dror Harats, Ginette Schiby, David Gailani, Hanna Levkovitz, Camila Avivi, Ilia Tamarin, Aviv Shaish, Ophira Salomon
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3): 475–481. Published online 2016 Jan 21. doi: 10.1161/ATVBAHA.115.306954
PMCID:
PMC4785893
AbstractArticlePDF–2.0M
10.
The polyphosphate–factor XII pathway drives coagulation in prostate cancer-associated thrombosis
Katrin F. Nickel, Göran Ronquist, Florian Langer, Linda Labberton, Tobias A. Fuchs, Carsten Bokemeyer, Guido Sauter, Markus Graefen, Nigel Mackman, Evi X. Stavrou, Gunnar Ronquist, Thomas Renné
Blood. 2015 Sep 10; 126(11): 1379–1389. Prepublished online 2015 Jul 7. doi: 10.1182/blood-2015-01-622811
PMCID:
PMC4566812
AbstractArticle
11.
Factor XI Anion-Binding Sites are required for Productive Interactions with Polyphosphate
Yipeng Geng, Ingrid M. Verhamme, Stephanie A. Smith, Qiufang Cheng, Mao-fu Sun, John P. Sheehan, James H. Morrissey, David Gailani
J Thromb Haemost. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: J Thromb Haemost. 2013 Nov; 11(11): 10.1111/jth.12414. doi: 10.1111/jth.12414
PMCID:
PMC3865764
AbstractArticlePDF–841K
12.
Regulation of the F11, Klkb1, Cyp4v3 Gene Cluster in Livers of Metabolically Challenged Mice
Huma Safdar, Audrey C. A. Cleuren, Ka Lei Cheung, Frank J. Gonzalez, Hans L. Vos, Yusuke Inoue, Pieter H. Reitsma, Bart J. M. van Vlijmen
PLoS One. 2013; 8(9): e74637. Published online 2013 Sep 16. doi: 10.1371/journal.pone.0074637
PMCID:
PMC3774739
AbstractArticlePDF–571K
13.
The dimeric structure of factor XI and zymogen activation
Yipeng Geng, Ingrid M. Verhamme, Stephen B. Smith, Mao-fu Sun, Anton Matafonov, Qiufang Cheng, Stephanie A. Smith, James H. Morrissey, David Gailani
Blood. 2013 May 9; 121(19): 3962–3969. Prepublished online 2013 Mar 20. doi: 10.1182/blood-2012-12-473629
PMCID:
PMC3650707
AbstractArticle
14.
Fibrin facilitates both innate and T cell-mediated defense against Yersinia pestis.
Deyan Luo, Shiuan Lin, Jr, Michelle A. Parent, Isis Mullarky Kanevsky, Frank M. Szaba, Lawrence W. Kummer, Debra K. Duso, Michael Tighe, Jim Hill, Andras Gruber, Nigel Mackman, David Gailani, Stephen T. Smiley
J Immunol. Author manuscript; available in PMC 2014 Apr 15.
Published in final edited form as: J Immunol. 2013 Apr 15; 190(8): 4149–4161. Published online 2013 Mar 13. doi: 10.4049/jimmunol.1203253
PMCID:
PMC3622124
AbstractArticlePDF–4.4M
15.
A CpG Mutational Hotspot in a ONECUT Binding Site Accounts for the Prevalent Variant of Hemophilia B Leyden
Alister P.W. Funnell, Michael D. Wilson, Benoit Ballester, Ka Sin Mak, Jon Burdach, Natisha Magan, Richard C.M. Pearson, Frederic P. Lemaigre, Kathryn M. Stowell, Duncan T. Odom, Paul Flicek, Merlin Crossley
Am J Hum Genet. 2013 Mar 7; 92(3): 460–467. doi: 10.1016/j.ajhg.2013.02.003
PMCID:
PMC3591849
AbstractArticlePDF–737K
16.
Factor XI-Deficient Mice Display Reduced Inflammation, Coagulopathy, and Bacterial Growth during Listeriosis
Deyan Luo, Frank M. Szaba, Lawrence W. Kummer, Lawrence L. Johnson, Erik I. Tucker, Andras Gruber, David Gailani, Stephen T. Smiley
Infect Immun. 2012 Jan; 80(1): 91–99. doi: 10.1128/IAI.05568-11
PMCID:
PMC3255681
AbstractArticlePDF–1.9M
17.
Protective roles for fibrin, tissue factor, PAI-1, and TAFI, but not FXI, during defense against the gram-negative bacterium Yersinia enterocolitica
Deyan Luo, Frank M. Szaba, Lawrence W. Kummer, Edward F. Plow, Nigel Mackman, David Gailani, Stephen T. Smiley
J Immunol. Author manuscript; available in PMC 2012 Aug 15.
Published in final edited form as: J Immunol. 2011 Aug 15; 187(4): 1866–1876. Published online 2011 Jul 1. doi: 10.4049/jimmunol.1101094
PMCID:
PMC3150340
AbstractArticlePDF–1.6M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo
Qiufang Cheng, Erik I. Tucker, Meghann S. Pine, India Sisler, Anton Matafonov, Mao-fu Sun, Tara C. White-Adams, Stephanie A. Smith, Stephen R. Hanson, Owen J. T. McCarty, Thomas Renné, András Gruber, David Gailani
Blood. 2010 Nov 11; 116(19): 3981–3989. Prepublished online 2010 Jul 15. doi: 10.1182/blood-2010-02-270918
PMCID:
PMC2981546
AbstractArticle
20.
Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo
Felicitas Müller, Nicola J. Mutch, Wolfdieter A. Schenk, Stephanie A. Smith, Lucie Esterl, Henri M. Spronk, Stefan Schmidbauer, William A. Gahl, James H. Morrissey, Thomas Renné
Cell. Author manuscript; available in PMC 2010 Dec 11.
Published in final edited form as: Cell. 2009 Dec 11; 139(6): 1143–1156. doi: 10.1016/j.cell.2009.11.001
PMCID:
PMC2796262
AbstractArticlePDF–2.3M

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