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Items: 1 to 20 of 198

1.
Hepatocytes differentiate into intestinal epithelial cells through a hybrid epithelial/mesenchymal cell state in culture
Shizuka Miura, Kenichi Horisawa, Tokuko Iwamori, Satoshi Tsujino, Kazuya Inoue, Satsuki Karasawa, Junpei Yamamoto, Yasuyuki Ohkawa, Sayaka Sekiya, Atsushi Suzuki
Nat Commun. 2024; 15: 3940. Published online 2024 May 15. doi: 10.1038/s41467-024-47869-2
PMCID:
PMC11096382
AbstractArticlePDF–11M
2.
Hepatocyte-specific METTL3 ablation by Alb-iCre mice (GPT), but not by Alb-Cre mice (JAX), resulted in acute liver failure (ALF) and postnatal lethality
Shihao Huang, Yingchun Li, Bingjie Wang, Zhihao Zhou, Yonglong Li, Lingjun Shen, Jinge Cong, Liuxin Han, Xudong Xiang, Jiawei Xia, Danhua He, Zhanlin Zhao, Ying Zhou, Qiwen Li, Guanqi Dai, Hanzhang Shen, Taoyan Lin, Aibing Wu, Junshuang Jia, Dong Xiao, Jing Li, Wentao Zhao, Xiaolin Lin
Aging (Albany NY) 2024 Apr 30; 16(8): 7217–7248. Published online 2024 Apr 22. doi: 10.18632/aging.205753
PMCID:
PMC11087113
AbstractArticlePDF–3.9M
3.
Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature
Ximeijia Zhang, Hongjuan He, Haoran Yu, Xiangqi Teng, Ziwen Wang, Chenghao Li, Jiahang Li, Haopeng Yang, Jiwei Shen, Tong Wu, Fengwei Zhang, Yan Zhang, Qiong Wu
Commun Biol. 2024; 7: 363. Published online 2024 Mar 23. doi: 10.1038/s42003-024-06038-3
PMCID:
PMC10960817
AbstractArticlePDF–3.1M
4.
TANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2 nuclear entry
Zhi Feng, Shengnan Liu, Ming Su, Chunyu Song, Chenyu Lin, Fangying Zhao, Yang Li, Xianyan Zeng, Yong Zhu, Yu Hou, Chunguang Ren, Huan Zhang, Ping Yi, Yong Ji, Chao Wang, Hongtao Li, Ming Ma, Lingfei Luo, Li Li
Nat Commun. 2024; 15: 2371. Published online 2024 Mar 15. doi: 10.1038/s41467-024-46720-y
PMCID:
PMC10943085
AbstractArticlePDF–6.1M
5.
Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations
Alessandro D’Ambrosio, Davide Bressan, Elisa Ferracci, Francesco Carbone, Patrizia Mulè, Federico Rossi, Caterina Barbieri, Elisa Sorrenti, Gaia Fiaccadori, Thomas Detone, Elena Vezzoli, Salvatore Bianchi, Chiara Sartori, Simona Corso, Akihisa Fukuda, Giovanni Bertalot, Andrea Falqui, Mattia Barbareschi, Alessandro Romanel, Diego Pasini, Fulvio Chiacchiera
Sci Adv. 2024 Mar 15; 10(11): eadh4435. Published online 2024 Mar 15. doi: 10.1126/sciadv.adh4435
PMCID:
PMC10942108
AbstractArticlePDF–9.8M
6.
Performance evaluation of different albumin assays for the detection of analbuminemia
Yi Zhang, Afsoun Abdollahi, Chaylen Andolino, Keigo Tomoo, Bailey M. Foster, Uma K. Aryal, Gregory C. Henderson
PLoS One. 2024; 19(3): e0300130. Published online 2024 Mar 6. doi: 10.1371/journal.pone.0300130
PMCID:
PMC10917273
AbstractArticlePDF–987K
7.
NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells
Hye Yeon Choi, Yicheng Zhu, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M. Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Exp Mol Med. 2024 Feb; 56(2): 461–477. Published online 2024 Feb 27. doi: 10.1038/s12276-024-01174-6
Correction in:
Exp Mol Med. 2024 Oct; 56(10): 2323.
PMCID:
PMC10907578
AbstractArticlePDF–9.4M
8.
HNF4A guides the MLL4 complex to establish and maintain H3K4me1 at gene regulatory elements
Avinash Thakur, Kwangjin Park, Rebecca Cullum, Bettina M. Fuglerud, Mina Khoshnoodi, Sibyl Drissler, Tabea L. Stephan, Jeremy Lotto, Donghwan Kim, Frank J. Gonzalez, Pamela A. Hoodless
Commun Biol. 2024; 7: 144. Published online 2024 Jan 31. doi: 10.1038/s42003-024-05835-0
PMCID:
PMC10830483
AbstractArticlePDF–13M
9.
Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis
Yadong Fu, Xiaoxi Zhou, Lin Wang, Weiguo Fan, Siqi Gao, Danyan Zhang, Zhiyang Ling, Yaguang Zhang, Liyan Ma, Fang Bai, Jiamei Chen, Bing Sun, Ping Liu
Redox Biol. 2024 Feb; 69: 103029. Published online 2024 Jan 3. doi: 10.1016/j.redox.2024.103029
PMCID:
PMC10808927
AbstractArticlePDF–18M
10.
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function
Yue Zhu, Qinqin Wang, Xinyu Xie, Cuihong Ma, Yuemei Qiao, Yu Zhang, Yanjun Wu, Yuan Gao, Jing Jiang, Xin Liu, Jianfeng Chen, Chen Li, Gaoxiang Ge
Cell Death Dis. 2024 Jan; 15(1): 55. Published online 2024 Jan 15. doi: 10.1038/s41419-024-06441-y
PMCID:
PMC10789742
AbstractArticlePDF–8.7M
11.
UHRF1 inhibition epigenetically reprograms cancer stem cells to suppress the tumorigenic phenotype of hepatocellular carcinoma
Yanchen Wang, Pengchao Hu, Fenfen Wang, Shaoyan Xi, Shasha Wu, Liangzhan Sun, Yuyang Du, Jingyi Zheng, Hui Yang, Mao Tang, Han Gao, Hao Luo, Yue Lv, Jingsong Yan, Xijun Ou, Yan Li
Cell Death Dis. 2023 Jun; 14(6): 381. Published online 2023 Jun 28. doi: 10.1038/s41419-023-05895-w
PMCID:
PMC10307895
AbstractArticlePDF–6.9M
12.
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Andrew S. Mendiola, Zhaoqi Yan, Karuna Dixit, Jeffrey R. Johnson, Mehdi Bouhaddou, Anke Meyer-Franke, Min-Gyoung Shin, Yu Yong, Ayushi Agrawal, Eilidh MacDonald, Gayathri Muthukumar, Clairice Pearce, Nikhita Arun, Belinda Cabriga, Rosa Meza-Acevedo, Maria del Pilar S. Alzamora, Scott S. Zamvil, Alexander R. Pico, Jae Kyu Ryu, Nevan J. Krogan, Katerina Akassoglou
Nat Immunol. 2023; 24(7): 1173–1187. Published online 2023 Jun 8. doi: 10.1038/s41590-023-01522-0
PMCID:
PMC10307624
AbstractArticlePDF–18M
13.
The circadian demethylation of a unique intronic deoxymethylCpG-rich island boosts the transcription of its cognate circadian clock output gene
Nisha Misra, Manohar Damara, Tao Ye, Pierre Chambon
Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2214062120. Published online 2023 Feb 15. doi: 10.1073/pnas.2214062120
PMCID:
PMC9974474
AbstractArticlePDF–1.1M
14.
A conditional Smg6 mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway
Georgia Katsioudi, René Dreos, Enes S. Arpa, Sevasti Gaspari, Angelica Liechti, Miho Sato, Christian H. Gabriel, Achim Kramer, Steven A. Brown, David Gatfield
Sci Adv. 2023 Jan; 9(2): eade2828. Published online 2023 Jan 13. doi: 10.1126/sciadv.ade2828
PMCID:
PMC9839329
AbstractArticlePDF–2.3M
15.
Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome
Santiago Vernia, Alexandra Lee, Norman J. Kennedy, Myoung Sook Han, Marta Isasa, Julie Cavanagh-Kyros, Armanda Roy, Aafreen Syed, Shanzah Chaudhry, Yvonne J. K. Edwards, Steven P. Gygi, Guangping Gao, Roger J. Davis
Proc Natl Acad Sci U S A. 2022 Nov 1; 119(44): e2210434119. Published online 2022 Oct 25. doi: 10.1073/pnas.2210434119
PMCID:
PMC9636906
AbstractArticlePDF–1.7M
16.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
17.
Oncogenic β-catenin stimulation of AKT2–CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer
Fangming Liu, Xiaochen Gai, Yuting Wu, Baohui Zhang, Xiaoyu Wu, Rongrong Cheng, Bufu Tang, Kezhuo Shang, Na Zhao, Weiwei Deng, Jie Chen, Zhengyi Zhang, Song Gu, Liang Zheng, Hongbing Zhang
Proc Natl Acad Sci U S A. 2022 Sep 27; 119(39): e2202157119. Published online 2022 Sep 19. doi: 10.1073/pnas.2202157119
PMCID:
PMC9522414
AbstractArticlePDF–2.8M
18.
A non-canonical vitamin K cycle is a potent ferroptosis suppressor
Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K. Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A. Pratt, Marcus Conrad
Nature. 2022; 608(7924): 778–783. Published online 2022 Aug 3. doi: 10.1038/s41586-022-05022-3
PMCID:
PMC9402432
AbstractArticlePDF–9.5M
19.
HNF4A modulates glucocorticoid action in the liver
A. Louise Hunter, Toryn M. Poolman, Donghwan Kim, Frank J. Gonzalez, David A. Bechtold, Andrew S.I. Loudon, Mudassar Iqbal, David W. Ray
Cell Rep. 2022 Apr 19; 39(3): 110697. Published online 2022 Apr 19. doi: 10.1016/j.celrep.2022.110697
PMCID:
PMC9380254
AbstractArticle
20.
Coordinated Cross-Talk Between the Myc and Mlx Networks in Liver Regeneration and Neoplasia
Huabo Wang, Jie Lu, Frances Alencastro, Alexander Roberts, Julia Fiedor, Patrick Carroll, Robert N. Eisenman, Sarangarajan Ranganathan, Michael Torbenson, Andrew W. Duncan, Edward V. Prochownik
Cell Mol Gastroenterol Hepatol. 2022; 13(6): 1785–1804. Published online 2022 Mar 5. doi: 10.1016/j.jcmgh.2022.02.018
PMCID:
PMC9046243
AbstractArticlePDF–3.8M

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