PMC Links for GEO Profiles (Select 129091986) - PMC

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Select item 89860731.

Modulation of gentamicin-induced acute kidney injury by myo-inositol oxygenase via the ROS/ALOX-12/12-HETE/GPR31 signaling pathway

Isha Sharma, Yingjun Liao, Xiaoping Zheng, Yashpal S. Kanwar

JCI Insight. 2022 Mar 22; 7(6): e155487. Published online 2022 Mar 22. doi: 10.1172/jci.insight.155487

PMCID:: PMC8986073

Abstract Article PDF–4.4M

Select item 88970162.

Myo-inositol oxygenase overexpression exacerbates cadmium-induced kidney injury via oxidant stress and necroptosis

Xiaoping Zheng, Fei Deng, Isha Sharma, Yashpal S. Kanwar

Am J Physiol Renal Physiol. 2022 Mar 1; 322(3): F344–F359. Published online 2022 Feb 1. doi: 10.1152/ajprenal.00460.2021

PMCID:: PMC8897016

Abstract Article

Select item 72432943.

Myo-inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulointerstitial Injury in Diabetes

Isha Sharma, Fei Deng, Yingjun Liao, Yashpal S. Kanwar

Diabetes. 2020 Jun; 69(6): 1248–1263. Published online 2020 Mar 13. doi: 10.2337/db19-0935

PMCID:: PMC7243294

Abstract Article PDF–6.7M

Select item 68191054.

Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule

Fei Deng, Isha Sharma, Yingbo Dai, Ming Yang, Yashpal S. Kanwar

J Clin Invest. 2019 Nov 1; 129(11): 5033–5049. Published online 2019 Oct 14. doi: 10.1172/JCI129903

PMCID:: PMC6819105

Abstract Article PDF–41M

Select item 63973715.

Myo-inositol oxygenase accentuates renal tubular injury initiated by endoplasmic reticulum stress

Tatsuya Tominaga, Isha Sharma, Yui Fujita, Toshio Doi, Aryana K. Wallner, Yashpal S. Kanwar

Am J Physiol Renal Physiol. 2019 Feb 1; 316(2): F301–F315. Published online 2018 Dec 12. doi: 10.1152/ajprenal.00534.2018

PMCID:: PMC6397371

Abstract Article

Select item 54077286.

Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI

Rajesh K. Dutta, Vinay K. Kondeti, Isha Sharma, Navdeep S. Chandel, Susan E. Quaggin, Yashpal S. Kanwar

J Am Soc Nephrol. 2017 May; 28(5): 1421–1436. Published online 2016 Nov 28. doi: 10.1681/ASN.2016070744

PMCID:: PMC5407728

Abstract Article

Select item 53976817.

High Glucose–Induced Hypomethylation Promotes Binding of Sp-1 to Myo-Inositol Oxygenase: Implication in the Pathobiology of Diabetic Tubulopathy

Isha Sharma, Rajesh K. Dutta, Neel K. Singh, Yashpal S. Kanwar

Am J Pathol. 2017 Apr; 187(4): 724–739. doi: 10.1016/j.ajpath.2016.12.011

PMCID:: PMC5397681

Abstract Article PDF–4.0M

Select item 47142208.

Transcriptional and Translational Modulation of myo-Inositol Oxygenase (Miox) by Fatty Acids: IMPLICATIONS IN RENAL TUBULAR INJURY INDUCED IN OBESITY AND DIABETES

Tatsuya Tominaga, Rajesh K. Dutta, Darukeshwara Joladarashi, Toshio Doi, Janardan K. Reddy, Yashpal S. Kanwar

J Biol Chem. 2016 Jan 15; 291(3): 1348–1367. Published online 2015 Nov 17. doi: 10.1074/jbc.M115.698191

PMCID:: PMC4714220

Abstract Article PDF–11M

Select item 44468759.

Disruption of Renal Tubular Mitochondrial Quality Control by Myo-Inositol Oxygenase in Diabetic Kidney Disease

Ming Zhan, Irtaza M. Usman, Lin Sun, Yashpal S. Kanwar

J Am Soc Nephrol. 2015 Jun; 26(6): 1304–1321. Published online 2014 Sep 30. doi: 10.1681/ASN.2014050457

PMCID:: PMC4446875

Abstract Article

Select item 367083910.

Kidney Specific Protein-Positive Cells Derived from Embryonic Stem Cells Reproduce Tubular Structures In Vitro and Differentiate into Renal Tubular Cells

Ryuji Morizane, Toshiaki Monkawa, Shizuka Fujii, Shintaro Yamaguchi, Koichiro Homma, Yumi Matsuzaki, Hideyuki Okano, Hiroshi Itoh

PLoS One. 2013; 8(6): e64843. Published online 2013 Jun 3. doi: 10.1371/journal.pone.0064843

PMCID:: PMC3670839

Abstract Article PDF–18M

Select item 357241011.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 307093713.

Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition

Jing Chen, Collin Melton, Nayoung Suh, Jeong Su Oh, Kathleen Horner, Fang Xie, Claudio Sette, Robert Blelloch, Marco Conti

Genes Dev. 2011 Apr; 25(7): 755–766. doi: 10.1101/gad.2028911

PMCID:: PMC3070937

Abstract Article PDF–965K

Select item 302253414.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582